Date published: 2025-9-7

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TORC2 抗体 (F-4): sc-271912

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说明书
  • TORC2抗体(F-4)是小鼠单克隆IgG2a κ, 在5篇文献中引用,规格为200 µg/ml
  • 与human起源的TORC2的C-terminus附近的肽图谱
  • 抗-TORC2 抗体 (F-4) 推荐用于 WB, IP, IF 和 ELISA,检测mouse, rat 和human 来源的 TORC2
  • 抗TORC2抗体(F-4)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 可用于ChIP的TransCruz试剂(sc-271912 X, 200 µg/0.1 ml)
  • 关于如何获取TORC2 (F-4): sc-271912免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP2a BP-HRP">m-IgG2a BP-HRPm-IgGκ BP-HRP是TORC2 Antibody (F-4) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与TORC2 Antibody (F-4) 打包提供(请参阅下面的订购信息)。

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関連項目

TORC2抗体(F-4)是一种IgG2a κ小鼠单克隆TORC2抗体,可通过WB、IP、IF和ELISA检测小鼠、大鼠和人源的TORC2。TORC2抗体(F-4)有非偶联抗TORC2抗体形式,以及多种偶联形式的抗TORC2抗体,包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。TORC(受调节的cAMP反应元件结合转导子)蛋白TORC1和TORC2是有效的CREB辅激活因子,以CRM1依赖的方式从细胞核输出。TORC蛋白的易位是cAMP诱导的CRE介导的基因表达激活中的保守步骤。TORC1和TORC2通过磷酸化依赖性相互作用发挥作用。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

TORC2 抗体 (F-4) 参考文献:

  1. 通过对哺乳动物细胞进行基因组规模的功能分析,鉴定 cAMP 反应元件结合蛋白辅激活因子家族。  |  Iourgenko, V., et al. 2003. Proc Natl Acad Sci U S A. 100: 12147-52. PMID: 14506290
  2. TORC:调节 CREB 活性的转换器。  |  Conkright, MD., et al. 2003. Mol Cell. 12: 413-23. PMID: 14536081
  3. CREB 辅激活因子 TORC2 发挥着钙和 cAMP 敏感性偶合检测器的作用。  |  Screaton, RA., et al. 2004. Cell. 119: 61-74. PMID: 15454081
  4. 通过调节 TORC 蛋白的核运输激活 cAMP 反应元件介导的基因表达。  |  Bittinger, MA., et al. 2004. Curr Biol. 14: 2156-61. PMID: 15589160
  5. 皮肤透明细胞色素痣--与 TORC1-MAML2 基因融合缔合作用的第三种肿瘤类型。  |  Behboudi, A., et al. 2005. Genes Chromosomes Cancer. 43: 202-5. PMID: 15729701
  6. CREB 辅激活因子 TORC2 是空腹葡萄糖代谢的关键调节因子。  |  Koo, SH., et al. 2005. Nature. 437: 1109-11. PMID: 16148943
  7. CBP 和 TORC2 之间的合作互动赋予 CREB 目的基因表达选择性。  |  Ravnskjaer, K., et al. 2007. EMBO J. 26: 2880-9. PMID: 17476304
  8. TORC2 调节生殖中心对 TCL1 肿瘤蛋白的抑制,促进 B 细胞发育并抑制转化体。  |  Kuraishy, AI., et al. 2007. Proc Natl Acad Sci U S A. 104: 10175-80. PMID: 17548807
  9. 葡萄糖通过调节 TORC2 的磷酸化来控制胰岛细胞中 CREB 的活性。  |  Jansson, D., et al. 2008. Proc Natl Acad Sci U S A. 105: 10161-6. PMID: 18626018
  10. 用新型 mTOR 激酶抑制剂靶向多发性骨髓瘤中的 TORC2。  |  Hoang, B., et al. 2010. Blood. 116: 4560-8. PMID: 20686120
  11. 质膜应激诱导 Slm 蛋白重新定位并激活 TORC2,从而促进鞘脂的合成。  |  Berchtold, D., et al. 2012. Nat Cell Biol. 14: 542-7. PMID: 22504275
  12. mTORc1/TORc2 抑制剂与拉帕替尼联用在体外膀胱癌中具有协同作用。  |  Becker, MN., et al. 2014. Urol Oncol. 32: 317-26. PMID: 24054871

订购信息

产品名称产品编号规格价格数量收藏夹

TORC2 抗体 (F-4)

sc-271912
200 µg/ml
$316.00

TORC2 (F-4): m-IgG Fc BP-HRP 套装

sc-529285
200 µg Ab; 10 µg BP
$354.00

TORC2 (F-4): m-IgGκ BP-HRP 套装

sc-522098
200 µg Ab, 40 µg BP
$354.00

TORC2 (F-4): m-IgG2a BP-HRP 套装

sc-547293
200 µg Ab; 10 µg BP
$354.00

TORC2 抗体 (F-4) X

sc-271912 X
200 µg/0.1 ml
$316.00

TORC2 抗体 (F-4) AC

sc-271912 AC
500 µg/ml, 25% agarose
$416.00

TORC2 抗体 (F-4) HRP

sc-271912 HRP
200 µg/ml
$316.00

TORC2 抗体 (F-4) FITC

sc-271912 FITC
200 µg/ml
$330.00

TORC2 抗体 (F-4) PE

sc-271912 PE
200 µg/ml
$343.00

TORC2 抗体 (F-4) Alexa Fluor® 488

sc-271912 AF488
200 µg/ml
$357.00

TORC2 抗体 (F-4) Alexa Fluor® 546

sc-271912 AF546
200 µg/ml
$357.00

TORC2 抗体 (F-4) Alexa Fluor® 594

sc-271912 AF594
200 µg/ml
$357.00

TORC2 抗体 (F-4) Alexa Fluor® 647

sc-271912 AF647
200 µg/ml
$357.00

TORC2 抗体 (F-4) Alexa Fluor® 680

sc-271912 AF680
200 µg/ml
$357.00

TORC2 抗体 (F-4) Alexa Fluor® 790

sc-271912 AF790
200 µg/ml
$357.00

TORC2 (F-4) 中和勝肽

sc-271912 P
100 µg/0.5 ml
$68.00

What application is the blocking peptide sc-271912 P appropriate for?

Asked by: Germaine
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-24
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Rated 3 out of 5 by from Antibody reviewThis antibody give me faint band in western blotting with mouse tissue samples.
Date published: 2018-06-14
Rated 5 out of 5 by from Good Western blotGreat Western blot data of TORC2 expression in non-transfected and mouse TORC2 transfected 293T whole cell lysates.
Date published: 2017-05-27
Rated 5 out of 5 by from WBnice, strong and specific band by Western blot with human kidney tissue lysates.
Date published: 2017-04-03
Rated 5 out of 5 by from Nice Western blot antibodyProduced nice, strong and specific band by Western blot in various samples
Date published: 2017-01-27
Rated 5 out of 5 by from Satisfactory Western Blot data of TORC2 expressionSatisfactory Western Blot data of TORC2 expression in HeLa whole cell lysate. -SCBT QC
Date published: 2015-04-18
Rated 5 out of 5 by from Great Western Blot data of TORC2 expressionGreat Western Blot data of TORC2 expression in Jurkat nuclear extract and JAR whole cell lysate . -SCBT QC
Date published: 2013-09-25
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TORC2 抗体 (F-4) is rated 4.7 out of 5 by 6.
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