Date published: 2025-9-7
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TGF beta Receptor 2/TGFBR2 Antibody (C-4) - Western Blotting - Image 2805
TGFβ RII (C-4): sc-17791. Hep G2 (A), A549 (B), TF-1 (C), 3T3-L1 (D), KNRK (E) 和 Mv 1 Lu (F) 全细胞裂解液中 TGFβ RII 表达的 Western 印迹分析.
TGFβ RII (C-4): sc-17791. Hep G2 (A), A549 (B), TF-1 (C), 3T3-L1 (D), KNRK (E) 和 Mv 1 Lu (F) 全细胞裂解液中 TGFβ RII 表达的 Western 印迹分析.

TGF beta Receptor 2/TGFBR2 抗体 (C-4): sc-17791

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寫評論提問

说明书
  • TGF beta Receptor 2/TGFBR2 抗体 C-4 是小鼠单克隆 IgG1 κ，TGF beta Receptor 2/TGFBR2抗体, 在37篇文献中引用，规格为200 µg/ml
  • 与氨基酸1-567结合，代表全长human起源的TFGβ RII
  • TGF beta Receptor 2/TGFBR2 抗体 (C-4) 推荐用于 WB, IP, IF, IHC(P) 和 ELISA，检测mouse, rat 和human 来源的 TGFβ RII
  • 抗TGF beta Receptor 2/TGFBR2抗体（C-4）可与琼脂糖结合用于IP；与HRP结合用于WB、IHC(P)和ELISA；与藻红蛋白或FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 和 Alexa Fluor® 647，用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统，例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680 和 Alexa Fluor® 790， 用于WB (NIR), IF 和 FCM; 以及用于近红外（NIR）检测系统，如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取TGF beta Receptor 2/TGFBR2 (C-4): sc-17791的免费10 µg小样，联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP 和 m-IgG1 BP-HRP 是 TGF beta Receptor 2/TGFBR2 抗体 (C-4) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与TGF beta Receptor 2/TGFBR2 抗体 (C-4) 组合成套装提供。 (请参阅下面的订购信息)。

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相关产品
描述
基因信息
说明书与实验方案
研究信息

関連項目

此外 TGF β Receptor 抗体 包括 TGF β RI, TGF β RII和TGF β RIII

TGFβ RII 抗体（C-4）是一种鼠单克隆 IgG1 kappa 轻链抗体，专门用于检测人、小鼠和大鼠的转化生长因子β受体 II（TGFβ RII），也称为 TGFBR2。TGFβ RII 单克隆抗体（C-4）靶向全长人TGFβ RII蛋白，包括1-567个氨基酸，可用于多种应用，包括蛋白质印迹（WB）、免疫沉淀（IP）、免疫荧光（IF）、免疫组织化学和酶联免疫吸附测定（ELISA）。TGFβ RII是一种重要的跨膜蛋白，在TGFβ信号传导通路中起着关键作用，该通路可调节细胞增殖、分化、凋亡等多种细胞过程。TGFβ RII通过与TGFβ配体结合，启动I型受体的磷酸化，从而激活下游Smad蛋白，后者可调节基因表达。该信号通路对于维持细胞稳态至关重要，对发育生物学、免疫调节和癌症进展具有重大意义。TGFβ RII功能失调与多种疾病有关，包括纤维化、自身免疫性疾病和肿瘤转移，这凸显了其作为治疗靶点的重要性。抗TGFβ RII抗体（C-4）有非结合 和偶联形式，如辣根过氧化物酶（HRP）、藻红蛋白（PE）、异硫氰酸荧光素（FITC）和Alexa Fluor®变体，为研究人员提供了多种选择。此外，TGFβ RII (C-4)抗体适用于检测TGFβ RII的两种同源物，它们由位于人类染色体3上的基因编码，通过可变剪接产生。TGFβ RII单克隆抗体(C-4)有助于在各种生物学和病理学背景下加深对TGFβ信号轴的理解和靶向。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

订购信息

产品名称产品编号规格价格数量收藏夹

TGF beta Receptor 2/TGFBR2 抗体 (C-4)

sc-17791
200 µg/ml
$316.00

TGF beta Receptor 2/TGFBR2 (C-4): m-IgG Fc BP-HRP 套装

sc-526570
200 µg Ab; 10 µg BP
$354.00

TGF beta Receptor 2/TGFBR2 (C-4): m-IgG1 BP-HRP 套装

sc-531943
200 µg Ab; 20 µg BP
$354.00

TGF beta Receptor 2/TGFBR2 抗体 (C-4) AC

sc-17791 AC
500 µg/ml, 25% agarose
$416.00

TGF beta Receptor 2/TGFBR2 抗体 (C-4) HRP

sc-17791 HRP
200 µg/ml
$316.00

TGF beta Receptor 2/TGFBR2 抗体 (C-4) FITC

sc-17791 FITC
200 µg/ml
$330.00

TGF beta Receptor 2/TGFBR2 抗体 (C-4) PE

sc-17791 PE
200 µg/ml
$343.00

TGF beta Receptor 2/TGFBR2 抗体 (C-4) Alexa Fluor® 488

sc-17791 AF488
200 µg/ml
$357.00

TGF beta Receptor 2/TGFBR2 抗体 (C-4) Alexa Fluor® 546

sc-17791 AF546
200 µg/ml
$357.00

TGF beta Receptor 2/TGFBR2 抗体 (C-4) Alexa Fluor® 594

sc-17791 AF594
200 µg/ml
$357.00

TGF beta Receptor 2/TGFBR2 抗体 (C-4) Alexa Fluor® 647

sc-17791 AF647
200 µg/ml
$357.00

TGF beta Receptor 2/TGFBR2 抗体 (C-4) Alexa Fluor® 680

sc-17791 AF680
200 µg/ml
$357.00

TGF beta Receptor 2/TGFBR2 抗体 (C-4) Alexa Fluor® 790

sc-17791 AF790
200 µg/ml
$357.00

この抗体を犬のフローサイトメトリーで使用できるか検討するために、サンプルをいただくことは可能でしょうか。 AF-488の標識のものを使用したく思っております。 お手数ですがご確認の程よろしくお願いいたします。

Asked by: Ayano
Thank you very much for your question. Please ask your Japanese dealer to apply for sample products. Website: www.cosmobio.co.jp ， www.iwai-chem.co.jp or www.nacalai.co.jp/ss/Contact/ 質問頂き、誠にありがとうございます。サンプル品の申請は日本のディーラーにお尋ねお願いします。ウェブサイト: www.cosmobio.co.jp ， www.iwai-chem.co.jp　又はwww.nacalai.co.jp/ss/Contact/
Answered by: Jiajun Z
Date published: 2025-03-19

Is it fine to use TGFb RII antibody (C-4) for WB in lysates from human PBMCs (RIPA buffer), in loading buffer Laemmli+5% beta-mercapto, boiled at 95ºC for 5min?

Asked by: MCE91
Thank you for your message. Please find our highly recommended protocol for WB on the following link: https://www.scbt.com/scbt/resources/protocols/western-immuno-blotting If you have further questions, please do not hesitate to contact our Technical Service by phone or email or by Live Chat.
Answered by: SCBT Heidelberg Support
Date published: 2018-11-27

Can I use TGFb RII Antibody (C-4): sc-17791 mouse monoclonal antibody for immunohistochemical staining of mouse tissue?

Asked by: sweetums
Yes. We recommend using a directly conjugated monoclonal antibody. NCAM (123C3): sc-7326 monoclonal antibody is available directly conjugated to either HRP (sc-17791 HRP), phycoerythrin (sc-17791 PE), fluorescein (sc-17791 FITC), Alexa Fluor® 488 (sc-17791 AF488), Alexa Fluor® 647 (sc-17791 AF647).
Answered by: Technical Support 13
Date published: 2018-07-10

Is it possible to use the AC conjugated TGFb RII Antibody (C-4): sc-17791 in both Western Blot and IP?

Asked by: sweetums
Thank you for your inquiry. We do not recommend the use of the AC conjugated form in Western blot. The AC conjugated form of the antibody is specifically used for IP. The unconjugated form of the antibody is the best choice when working in multiple applications.
Answered by: Technical Support 13
Date published: 2017-01-12
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Rated 1 out of 5 by from Didn't work for IHC-PDidn't work for IHC-P. Don't know if it works for Western
Date published: 2022-05-18
Rated 4 out of 5 by from GoodTGFBR2 antibody detected reasonably in human stromal cells by IF and IHC(P).
Date published: 2021-09-16
Rated 1 out of 5 by from ImmunofluorescenceI used the anti-TGF-beta receptor II antibody at 1:100 dilution. The sample (cultured epithelial cell) was fixed with 4% PFA followed by chilled methanol. Unfortunately, I could not detect this signal because of very low signal.
Date published: 2020-09-02
Rated 1 out of 5 by from Not recognizing the correct bandI tested the free antibody sample from Santa Cruz with my TGFb RII wild type and knockout cell lysate. Unfortunately, this antibody did not recognize TGFb RII. Even though there were multiple bands on the blot, none of them show difference between WT and KO samples.
Date published: 2018-05-10
Rated 1 out of 5 by from TGFβ RII Antibody (C-4)I used whole heart homogenates for this WB. No bands showed up on the predicted size. Just a non-specific one at around 50kDa.
Date published: 2017-12-05
Rated 1 out of 5 by from Did not work for meInterestingly, TGFbeta RII (E-6) worked pretty well for my western blots. Not sure why this did not work.
Date published: 2017-11-06
Rated 5 out of 5 by from RecommendedA clear band of WB was shown in the cell line. I chose 1/500 dilution, which was very satisfactory for this result.
Date published: 2017-10-25
Rated 4 out of 5 by from GoodThough there are some none specific background, the main band is quite clear.
Date published: 2017-10-06
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TGF beta Receptor 2/TGFBR2 抗体 (C-4) is rated 3.3 out of 5 by 27.
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