Talniflumate CAS: 66898-62-2
MF: C21H13F3N2O4
MW: 414.34
An inhibitor of Cox and Cl-/HCO3- exchange.

Talniflumate (CAS 66898-62-2)

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 122ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
备用名: Lomucin; Somalgen; Talniflumatum
应用; Talniflumate is an inhibitor of Cox and Cl-/HCO3- exchange
CAS号码: 66898-62-2
纯度: ≥98%
分子量: 414.34
分子式: C21H13F3N2O4
仅供科研使用。不可用于诊断或治疗。
* 参考分析证明 大量特定数据 (包括水 含量).

Talniflumate is a calcium-activated chloride channel (hCLCA1/mCLCA3) blocker that reduces mucin synthesis and release in animal models and cell culture. Talniflumate possesses anti-inflammatory actions via inhibition of Cox (cyclooxygenase) and inhibits Cl-/HCO3- exchange activity. Talniflumate increases survival in a cystic fibrosis mouse model of distal intestinal obstructive syndrome.


参考文献

1. Knight, D., 2004. Curr. Opin. Invest. Drugs. 5: 557-562.
2. Walker, N.M., et al. 2006. J. Pharmacol. Exp. Ther. 317: 275-283.

物理状态 :
Solid
溶解度 :
Soluble in DMSO (25 mM).
保存 :
Store at -20° C
熔点 :
165-170° C
沸点 :
~534.57° C at 760 mmHg (Predicted)
密度 :
~1.5 g/cm3 (Predicted)
折射率 :
n20D 1.63 (Predicted)
pK值 :
pKb: 2.72 (Predicted)
仅供科研使用。不可用于诊断或治疗。
RTECS :
QT2999200
PubChem CID :
MDL 号码 :
MFCD00866135
Beilstein 注册 :
0503261
SMILES :
C1=CC=C2C(=C1)C(OC2=O)OC(=O)C3=C(N=CC=C3)NC4=CC=CC(=C4)C(F)(F)F

下载SDS

分析证明书

在PDF文件上阅读,打印和批注,Adobe阅读器是必须的

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 107ms
  • QUESTIONS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 8ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;

圣克鲁斯生物技术在生物医药研究市场的产品开发方面处于世界领先地位。欢迎 致电我们的免费电话(021) 800-820-8626。 版权 ©, 2007-2021圣克鲁斯生物技术。版权所有。“Santa Cruz Biotechnology”,圣克鲁斯生物技 术的 商标,“Santa Cruz Animal Health”,“San Juan Ranch”,“Supplement of Champions”,San Juan Ranch的商标,“Ultracruz”,“Chemcruz”,“Immunocruz”,“Exactacruz”和“EZ Touch”都是圣克鲁斯生物技术的注册商标。所有的商标都归其各自拥有者所有。