Date published: 2025-9-6
访问圣克鲁斯动物健康

021-6093-6350

SCBT Portrait Logo
Seach Input
联系我们
登陆账户
快速订购
购物车 (0)
Syntaxin 1 Antibody (HPC-1) - Western Blotting - Image 363174
合成轴突蛋白 1 抗体 (HPC-1): sc-12736. A-10 (A) 和 NIH/3T3 (B) 全细胞裂解液中 Syntaxin 1 表达的 Western 印迹分析.
合成轴突蛋白 1 抗体 (HPC-1): sc-12736. A-10 (A) 和 NIH/3T3 (B) 全细胞裂解液中 Syntaxin 1 表达的 Western 印迹分析.

Syntaxin 1 抗体 (HPC-1): sc-12736

4.4(18)
寫評論提問

说明书
  • Syntaxin 1 抗体 HPC-1 是小鼠单克隆 IgG1 κ，Syntaxin 1抗体, 在85篇文献中引用，规格为200 µg/ml
  • 免疫rat物种的Syntaxin 1
  • Syntaxin 1 抗体 (HPC-1) 推荐用于 WB, IP, IF, IHC(P) 和 ELISA，检测mouse, rat 和human 来源的 Syntaxin 1A and Syntaxin 1B
  • 抗Syntaxin 1抗体（HPC-1）可与琼脂糖结合用于IP；与HRP结合用于WB、IHC(P)和ELISA；与藻红蛋白或FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 和 Alexa Fluor® 647，用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统，例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680 和 Alexa Fluor® 790， 用于WB (NIR), IF 和 FCM; 以及用于近红外（NIR）检测系统，如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取Syntaxin 1 (HPC-1): sc-12736的免费10 µg小样，联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG1 BP-HRP 是 Syntaxin 1 抗体 (HPC-1) 在 WB and IHC(P) 应用中的首选二抗检测试剂。该试剂现与Syntaxin 1 抗体 (HPC-1) 组合成套装提供。 (请参阅下面的订购信息)。

快捷链接

相关产品
描述
基因信息
说明书与实验方案
研究信息

関連項目

此外 Syntaxin 抗体 包括 Syntaxin 1, Syntaxin 11, Syntaxin 18, Syntaxin 2, syntaxin 3, Syntaxin 4, Syntaxin 5, Syntaxin 7和Syntaxin 8

Syntaxin 1 抗体（HPC-1）是一种小鼠单克隆 IgG1 kappa 轻链抗体，可通过蛋白质印迹（WB）、免疫沉淀（IP）、免疫荧光（IF）、免疫组织化学和酶联免疫吸附测定（ELISA）检测小鼠、大鼠和人类来源的 Syntaxin 1 蛋白。抗Syntaxin 1抗体（HPC-1）有非结合型和多种结合型，包括琼脂糖、辣根过氧化物酶（HRP）、藻红蛋白（PE）、异硫氰酸荧光素（FITC）和多种Alexa Fluor®结合物。Syntaxin 1在囊泡运输中起着至关重要的作用，而囊泡运输对于真核细胞的存活至关重要。Syntaxin 1主要位于突触囊泡膜上，对于囊泡与质膜融合至关重要，而囊泡与质膜融合是神经递质释放所必需的过程。Syntaxin 1对于突触传递至关重要，它与SNARE复合体中的其他蛋白（包括突触素和SNAP-25）相互作用，促进囊泡对接和融合。Syntaxin 1功能紊乱可导致各种神经系统疾病，这凸显了Syntaxin 1在维持神经元完整性和神经系统内通信方面的重要性。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Syntaxin 1 抗体 (HPC-1) 参考文献:

  1. 突触融合蛋白1是下菱形唇迁移神经元的DCC/Netrin-1依赖性趋化吸引所必需的。  |  Cotrufo, T., et al. 2012. Eur J Neurosci. 36: 3152-64. PMID: 22946563
  2. 钙依赖性分泌活化蛋白 1（CAPS1）与突触融合蛋白-1 的结合模式与 Munc13-1 不同。  |  Parsaud, L., et al. 2013. J Biol Chem. 288: 23050-63. PMID: 23801330
  3. 钙通过磷脂酰肌醇 4,5-二磷酸促进突触融合蛋白 1 中尺度结构域的形成  |  Milovanovic, D., et al. 2016. J Biol Chem. 291: 7868-76. PMID: 26884341
  4. 重新研究突触融合蛋白-1 在小鼠中枢突触囊泡融合过程中的 N 端结构域。  |  Vardar, G., et al. 2021. Elife. 10: PMID: 34427183
  5. 囊泡转运受体的 syntaxin 家族。  |  Bennett, MK., et al. 1993. Cell. 74: 863-73. PMID: 7690687
  6. 突触珠蛋白与突触素的结合：控制外吞融合机的潜在机制  |  Edelmann, L., et al. 1995. EMBO J. 14: 224-31. PMID: 7835333
  7. 由突触珠蛋白, 语法蛋白和 SNAP25 组成的突触核心复合体形成了高亲和力的 alpha-SNAP 结合位点。  |  McMahon, HT. and Südhof, TC. 1995. J Biol Chem. 270: 2213-7. PMID: 7836452
  8. 神经系统中与蛋白质有关的外排。  |  Yamaguchi, K. and Akagawa, K. 1994. Neurosci Res. 20: 289-92. PMID: 7870381
  9. 突触小泡膜融合复合体：梭菌类神经毒素对组装的作用。  |  Hayashi, T., et al. 1994. EMBO J. 13: 5051-61. PMID: 7957071
  10. 突触标记蛋白（p65）在调节外吞中的作用  |  Elferink, LA., et al. 1993. Cell. 72: 153-9. PMID: 8422678
  11. α-SNAP对NSF ATP酶活性的刺激是SNARE复合物解体和外吞所必需的。  |  Barnard, RJ., et al. 1997. J Cell Biol. 139: 875-83. PMID: 9362506
  12. 突触外泌核心复合体的结构组织。  |  Lin, RC. and Scheller, RH. 1997. Neuron. 19: 1087-94. PMID: 9390521

订购信息

产品名称产品编号规格价格数量收藏夹

Syntaxin 1 抗体 (HPC-1)

sc-12736
200 µg/ml
$316.00

Syntaxin 1 (HPC-1): m-IgG1 BP-HRP 套装

sc-531636
200 µg Ab; 20 µg BP
$354.00

Syntaxin 1 抗体 (HPC-1) AC

sc-12736 AC
500 µg/ml, 25% agarose
$416.00

Syntaxin 1 抗体 (HPC-1) HRP

sc-12736 HRP
200 µg/ml
$316.00

Syntaxin 1 抗体 (HPC-1) FITC

sc-12736 FITC
200 µg/ml
$330.00

Syntaxin 1 抗体 (HPC-1) PE

sc-12736 PE
200 µg/ml
$343.00

Syntaxin 1 抗体 (HPC-1) Alexa Fluor® 488

sc-12736 AF488
200 µg/ml
$357.00

Syntaxin 1 抗体 (HPC-1) Alexa Fluor® 546

sc-12736 AF546
200 µg/ml
$357.00

Syntaxin 1 抗体 (HPC-1) Alexa Fluor® 594

sc-12736 AF594
200 µg/ml
$357.00

Syntaxin 1 抗体 (HPC-1) Alexa Fluor® 647

sc-12736 AF647
200 µg/ml
$357.00

Syntaxin 1 抗体 (HPC-1) Alexa Fluor® 680

sc-12736 AF680
200 µg/ml
$357.00

Syntaxin 1 抗体 (HPC-1) Alexa Fluor® 790

sc-12736 AF790
200 µg/ml
$357.00

Is Syntaxin 1 (HPC-1), sc-12736, available directly conjugated to HRP or fluorescent dyes?

Asked by: TinTin
Thank you for your question! Yes, sc-12736 is available conjugated to agarose (sc-12736 AC), HRP (sc-12736 HRP), phycoerythrin (sc-12736 PE), fluorescein (sc-12736 FITC), Alexa Fluor® 488 (sc-12736 AF488) and Alexa Fluor® 647 (sc-12736 AF647).
Answered by: Technical Support 2
Date published: 2017-01-13

What is the best secondary to use with this antibody in Western Blot?

Asked by: TinTin
Thank you for your question. We recommend using our Mouse IgG kappa Binding Protein HRP, sc-516102. A complete list of available binding proteins is available on our website here: https://www.scbt.com/scbt/browse/support-products-mouse-igg-binding-proteins/_/N-ecrety
Answered by: Technical Support 7
Date published: 2017-01-10
  • y_2025, m_8, d_27, h_4CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_2
  • loc_zh_CN, sid_12736, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getContent, 100ms
  • QUESTIONS, PRODUCT
Rated 4 out of 5 by from works for WBThe antibody worked well in western blot experiments
Date published: 2023-01-19
Rated 4 out of 5 by from Worked well by WBWorked well by Western Blot. SCBT Publication Review
Date published: 2019-11-14
Rated 1 out of 5 by from IF: No signals :(Unfortunately, did not work on cryosections (10µm) from human retinal organoids (IF 1:200/1:100/1:50).
Date published: 2019-07-23
Rated 4 out of 5 by from Good antibodyThis antibody worked very well with fixed frozen mouse tissue sections for IF
Date published: 2018-10-03
Rated 5 out of 5 by from amazing IHCI got an amazing fluorescent IHC on mouse retina frozen section using this antibody at 1:400. Should be able to use it at higher dilution.
Date published: 2018-05-25
Rated 5 out of 5 by from WB in NG108-15 cellsI was able to detect a strong signal using WB performed in NG108-15 cells
Date published: 2018-05-17
Rated 5 out of 5 by from Great immunostainingI used this antibody on mouse retina frozen section (10 um) at 1/200 dilution in blocking solution (2% NHS/2 mg/mL BSA in 1x PBS/0.1% Triton X-100/0.05% NaN3) O/N at 4ºC.
Date published: 2017-11-06
Rated 5 out of 5 by from Successful application of this antibody in IFSuccessful application of this antibody in IF, using human tissues.
Date published: 2017-09-17
  • y_2025, m_8, d_27, h_4
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_18
  • loc_zh_CN, sid_12736, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getReviews, 16ms
  • REVIEWS, PRODUCT
Syntaxin 1 抗体 (HPC-1) is rated 4.4 out of 5 by 18.
  • y_2025, m_8, d_27, h_4
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_18
  • loc_zh_CN, sid_12736, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 102ms
  • REVIEWS, PRODUCT
021-6093-6350
访问 Santa Cruz Animal Health|访问 San Juan Ranch
Santa Cruz Biotechnology, Inc. 是生物医学研究市场产品开发的世界领导者。请拨打0086-021-60936350联系我们。
版权所有© 2007-2025 Santa Cruz Biotechnology, Inc. 保留所有权利。”Santa Cruz Biotechnology” 和Santa Cruz Biotechnology, Inc.的商标，”Santa Cruz Animal Health”, “San Juan Ranch”, “Supplement of Champions”, San Juan Ranch的商标，”UltraCruz”, “ChemCruz”, “ImmunoCruz”, “ExactaCruz”, 和 “EZ Touch”是Santa Cruz Biotechnology, Inc.的注册商标。所有商标均为其各自所有者的财产。