CD138/SDC1/Syndecan-1 Antibody (B-A38): sc-65337
- CD138/SDC1/Syndecan-1 Antibody (B-A38) is a mouse monoclonal IgG1, cited in 1 publications, provided at 100 µg/ml
- raised against U266 myeloma cell line of human origin
- recommended for detection of Syndecan-1 of mouse, rat and human origin by WB, IP, IF and FCM
- See CD138/SDC1/Syndecan-1 (A-6): sc-390791 for CD138/SDC1/Syndecan-1 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for CD138/SDC1/Syndecan-1 Antibody (B-A38). This work is in progress.
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Syndecan-1 Antibody (B-A38) is a mouse monoclonal IgG1 antibody that detects Syndecan-1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). Syndecan-1, also known as CD138, is a type I integral membrane proteoglycan that plays a crucial role in cell signaling and adhesion by serving as a receptor for the extracellular matrix. Syndecan-1 (B-A38) antibody recognizes pre-B cells, immature B cells, and plasma cells, highlighting Syndecan-1′s importance in the immune response, while localization on basolateral surfaces of epithelial cells and endothelial cells of sprouting capillaries underscores Syndecan-1′s role in tissue organization and vascular development. Syndecan-1 interacts with various extracellular matrix components, including collagens, fibronectin, and thrombospondin, facilitating cell-matrix interactions that are essential for maintaining tissue architecture and promoting cellular communication. Syndecan-1′s co-localization with actin-rich filaments suggests a link between the cytoskeleton and extracellular matrix, thereby influencing cellular shape and motility. Anti-Syndecan-1 antibody (B-A38) serves as an invaluable tool for researchers investigating the dynamics of cell adhesion and signaling pathways in various biological contexts.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
CD138/SDC1/Syndecan-1 Antibody (B-A38) References:
- Syndecan-1 in B lymphoid malignancies. | Sanderson, RD. and Børset, M. 2002. Ann Hematol. 81: 125-35. PMID: 11904737
- Syndecan-1 and Its Expanding List of Contacts. | Stepp, MA., et al. 2015. Adv Wound Care (New Rochelle). 4: 235-249. PMID: 25945286
- Syndecan-1 restitution by plasma after hemorrhagic shock. | Kozar, RA. and Pati, S. 2015. J Trauma Acute Care Surg. 78: S83-6. PMID: 26002270
- Glycobiology of syndecan-1 in bacterial infections. | Aquino, RS., et al. 2018. Biochem Soc Trans. 46: 371-377. PMID: 29523771
- Involvement of Syndecan-1 and Heparanase in Cancer and Inflammation. | Teixeira, FCOB. and Götte, M. 2020. Adv Exp Med Biol. 1221: 97-135. PMID: 32274708
- The Lacritin-Syndecan-1-Heparanase Axis in Dry Eye Disease. | Dias-Teixeira, K., et al. 2020. Adv Exp Med Biol. 1221: 747-757. PMID: 32274735
- Syndecan-1 (CD138) as a Pathogenesis Factor and Therapeutic Target in Breast Cancer. | Sheta, M. and Götte, M. 2021. Curr Med Chem. 28: 5066-5083. PMID: 34191695
- Syndecan-1 as a severity biomarker for patients with trauma. | Suzuki, K., et al. 2022. Front Med (Lausanne). 9: 985955. PMID: 36237551
- Role of Heparanase and Syndecan-1 in HSV-1 Release from Infected Cells. | Sharma, P., et al. 2022. Viruses. 14: PMID: 36298711
- Syndecan-1 shedding destroys epithelial adherens junctions through STAT3 after renal ischemia/reperfusion injury. | Guo, M., et al. 2023. iScience. 26: 108211. PMID: 37942007
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD138/SDC1/Syndecan-1 Antibody (B-A38) | sc-65337 | 100 µg/ml | $322.00 |