Date published: 2025-9-7

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SUN2 抗体 (G-5): sc-377459

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说明书
  • SUN2 抗体 G-5 是小鼠单克隆 IgG3 κ,SUN2抗体, 在2篇文献中引用,规格为200 µg/ml
  • 特异性抗原位于human物种的SUN2的内部区域内的氨基酸95-125之间
  • 推荐用于 mouse, rat 和 human 来源的SUN2 WB, IP, IF 和 ELISA检测
  • 关于如何获取SUN2 (G-5): sc-377459免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG3 BP-HRPm-IgGκ BP-HRP是SUN2 Antibody (G-5) 适用于 WB 应用。 的首选辅助检测试剂,这些试剂现与SUN2 Antibody (G-5) 打包提供(请参阅下面的订购信息)。

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関連項目

SUN2抗体(G-5)是一种IgG3 κ小鼠单克隆SUN2抗体(也称为SUN2抗体),可通过WB、IP、IF和ELISA检测小鼠、大鼠和人类的SUN2蛋白。SUN2抗体(G-5)既可以是非偶联的抗SUN2抗体,也可以是多种偶联形式的。SUN2(sad1/unc-84蛋白样2),也称为UNC84B(unc-84同源B)、FRIGG、KIAA0668或RAB5IP,是一种包含717个氨基酸的单次跨膜蛋白,含有一个SUN结构域,并定位于细胞核和内体的膜上。SUN2在多种组织中广泛表达,包括肺、肌肉和心脏,与Rab 5A相互作用,并可能在同型内体融合中发挥作用。编码SUN2的基因定位于人类22号染色体,该染色体包含500多个基因,是人类第二小的染色体。定位于22号染色体的几个基因突变与Phelan-McDermid综合征、2型神经纤维瘤病、自闭症和精神分裂症的发展有关。此外,9号和22号染色体之间的易位可能导致费城染色体的形成,随后产生新型融合蛋白BCR-Abl,这是一种在多种白血病中发现的强效细胞增殖激活剂。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

SUN2 抗体 (G-5) 参考文献:

  1. 缺少的 (L) UNC?  |  Raff, JW. 1999. Curr Biol. 9: R708-10. PMID: 10508607
  2. 同型内质体融合所需的新型膜锚Rab5互作蛋白  |  Hoffenberg, S., et al. 2000. J Biol Chem. 275: 24661-9. PMID: 10818110
  3. 通过磷酸特异性抗体富集鉴定丝氨酸/苏氨酸磷酸化蛋白质的质谱蛋白质组学方法:鉴定作为蛋白激酶 A 底物的新型蛋白质 Frigg。  |  Grønborg, M., et al. 2002. Mol Cell Proteomics. 1: 517-27. PMID: 12239280
  4. 人类心脏组织中差异表达基因的分离。  |  Sun, G., et al. 2002. Biochim Biophys Acta. 1588: 241-6. PMID: 12393179
  5. 通过减法蛋白质组学发现与疾病有潜在联系的核膜蛋白。  |  Schirmer, EC., et al. 2003. Science. 301: 1380-2. PMID: 12958361
  6. 细胞核与细胞质的耦合:LINC 复合物的作用  |  Crisp, M., et al. 2006. J Cell Biol. 172: 41-53. PMID: 16380439
  7. 定域 SUN 蛋白在核包膜和中心体上的结构特征。  |  Wang, Q., et al. 2006. DNA Cell Biol. 25: 554-62. PMID: 17132086
  8. 蛋白质组分析揭示了在多个细胞过程中 Hrs 泛素交互基序介导的泛素信号转导。  |  Pridgeon, JW., et al. 2009. FEBS J. 276: 118-31. PMID: 19019082

订购信息

产品名称产品编号规格价格数量收藏夹

SUN2 抗体 (G-5)

sc-377459
200 µg/ml
$316.00

SUN2 (G-5): m-IgGκ BP-HRP 套装

sc-523334
200 µg Ab, 40 µg BP
$354.00

SUN2 (G-5): m-IgG3 BP-HRP 套装

sc-550357
200 µg Ab; 40 µg BP
$354.00

SUN2 (G-5) 中和勝肽

sc-377459 P
100 µg/0.5 ml
$68.00

Hello, I would like to ask if I can get the free sample of this antibodies. Best, Jakub Kaplan

Asked by: Jakub Kaplan
Thank you for your question. Please contact Technical Service for more information on how to receive a 10 μg sample of our well characterized monoclonal antibody.
Answered by: Technical Support
Date published: 2018-12-05

What application is the blocking peptide sc-377459 P appropriate for?

Asked by: Dr Ninau Qelp
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-25
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Rated 5 out of 5 by from Excellent for WBit works excellent for WB in our lab, will keep usinig it
Date published: 2017-09-18
Rated 1 out of 5 by from Don't think it works for mouse cellsI tested this on mouse SMC, but does not detect any band for WB and signal is unspecific(non-nuclear) for IF
Date published: 2017-08-23
Rated 5 out of 5 by from Produced positive Western blot data of SUN2Produced positive Western blot data of SUN2 expression in Jurkat whole cell lysate. -SCBT QC
Date published: 2013-09-07
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SUN2 抗体 (G-5) is rated 3.7 out of 5 by 3.
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