Sulconazole nitrate salt 的分子结构, CAS编号: 61318-91-0
Sulconazole nitrate salt (CAS 61318-91-0)
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备用名:
1-(2-[p-Chlorobenzylthio]-2-[2,4-dichlorophenyl]ethyl)-1H-imidazole
应用:
Sulconazole nitrate salt 是一种抗真菌剂，它通过抑制固醇合成来阻止真菌生长
CAS号码:
61318-91-0
纯度:
≥95%
分子量:
460.76
分子式:
C18H15Cl3N2S•HNO3
仅供科研使用。不可用于诊断或治疗。
* 参考分析证明 大量特定数据 (包括水 含量).
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Sulconazole nitrate salt是一种抗菌剂，具有广泛的有效性，通过干扰真菌细胞膜的重要成分麦角固醇的产生来阻止真菌的生长。此外，Sulconazole nitrate salt通过阻碍脂肪酸合成来抑制细菌和其他微生物的增殖。它的作用方式包括与质膜中的脂肪酸结合，从而阻碍它们融入磷脂双层。因此，这种破坏降低了细胞膜的流动性，导致结构完整性受损，细胞通透性增加。
Sulconazole nitrate salt (CAS 61318-91-0) 参考文献
- Contact dermatitis and cross-sensitivity from sulconazole nitrate. | Machet, L., et al. 1992. Contact Dermatitis. 26: 352-3. PMID: 1395603
- Sulconazole nitrate 1% cream in the treatment of chronic moccasin-type tinea pedis caused by Trichophyton rubrum. | Akers, WA., et al. 1989. J Am Acad Dermatol. 21: 686-9. PMID: 2681281
- Structural confirmation of sulconazole sulfoxide as the primary degradation product of sulconazole nitrate. | Xu, Q., et al. 2018. J Pharm Anal. 8: 96-102. PMID: 29736295
- Percutaneous absorption of sulconazole nitrate in humans. | Franz, TJ. and Lehman, P. 1988. J Pharm Sci. 77: 489-91. PMID: 3171926
- Microemulsion Based Gel of Sulconazole Nitrate for Topical Application. | Payyal, SP., et al. 2020. Turk J Pharm Sci. 17: 259-264. PMID: 32636702
- Biliverdin regulates NR2E3 and zebrafish retinal photoreceptor development. | Connor, B., et al. 2022. Sci Rep. 12: 7310. PMID: 35508617
- Influence of growth phase on the susceptibility of Candida albicans to butoconazole, oxiconazole, and sulconazole. | Beggs, WH. 1985. J Antimicrob Chemother. 16: 397-9. PMID: 3902762
- Automated high-performance liquid chromatographic column switching technique for the on-line clean-up and analysis of drugs in topical cream formulations. | Conley, DL. and Benjamin, EJ. 1983. J Chromatogr. 257: 337-44. PMID: 6853627
- A double-blind parallel study of sulconazole nitrate 1% cream compared with miconazole nitrate 2% cream in dermatophytoses. | Gip, L. and Forsström, S. 1983. Mykosen. 26: 231-41. PMID: 6877272
- Sulconazole in the therapy of dermatomycoses in Nigeria. | Gugnani, HC., et al. 1997. Mycoses. 40: 139-41. PMID: 9375503
抑制剂：
Heme Oxygenase.订购信息
| 产品名称 | 产品编号 | 规格 | 价格 | 数量 | 收藏夹 | |
Sulconazole nitrate salt, 1 g | sc-236948 | 1 g | $194.00 | |||
Sulconazole nitrate salt, 5 g | sc-236948A | 5 g | $604.00 |