Date published: 2026-5-17

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Spiramycin I-d3 (CAS 1355452-20-8)

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Alternate Names:
9-O-[(2R,5S,6R)-5-(Dimethylamino)tetrahydro-6-methyl-2H-pyran-2-yl]leucomycin V-d3; Foromacidin A-d3; Spiramycin A-d3
Application:
Spiramycin I-d3 is an antibiotic substance
CAS Number:
1355452-20-8
Purity:
≥95%
Molecular Weight:
846.07
Molecular Formula:
C43H71D3N2O14
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Spiramycin I-d3 is a deuterated version of Spiramycin I, a macrolide compound, in which three hydrogen atoms are replaced with deuterium. This isotopic substitution enhances the molecule′s stability and alters its physical properties, such as its vibrational profile, without changing its chemical structure. The introduction of deuterium atoms is particularly beneficial in analytical research, where Spiramycin I-d3 is used as an internal standard to improve the accuracy and precision of mass spectrometric analyses. By using this deuterated compound, researchers can differentiate the analyte from similar molecules and reduce background noise, which is crucial in complex biological or environmental matrices where precise quantification is vital. The specific use of Spiramycin I-d3 in research focuses on studying the metabolism and environmental degradation pathways of spiramycin. In these studies, Spiramycin I-d3 helps in delineating and quantifying the biotransformation products of spiramycin under various conditions. Additionally, this compound is employed in environmental science research to track the fate of spiramycin in ecosystems, helping to understand its persistence and the potential for bioaccumulation. Such studies are essential for assessing the environmental impact of bioactive compounds and designing strategies for mitigating their presence in the environment.


Spiramycin I-d3 (CAS 1355452-20-8) References

  1. Screening and confirmatory method for multiclass determination of 62 antibiotics in meat.  |  Moretti, S., et al. 2016. J Chromatogr A. 1429: 175-88. PMID: 26726937
  2. Multiclass method for the determination of 62 antibiotics in milk.  |  Moretti, S., et al. 2016. J Mass Spectrom. 51: 792-804. PMID: 27490945
  3. The analysis of tetracyclines, quinolones, macrolides, lincosamides, pleuromutilins, and sulfonamides in chicken feathers using UHPLC-MS/MS in order to monitor antibiotic use in the poultry sector.  |  Jansen, LJM., et al. 2017. Anal Bioanal Chem. 409: 4927-4941. PMID: 28674821
  4. Transfer of a Multiclass Method for over 60 Antibiotics in Food from High Resolution to Low Resolution Mass Spectrometry.  |  Giusepponi, D., et al. 2019. Molecules. 24: PMID: 31412663
  5. A liquid chromatography coupled to tandem mass spectrometry method for the quantification of spiramycin and its active metabolite neospiramycin in milk of major and minor species: Validation using the accuracy profile.  |  Tardiveau, J., et al. 2021. J Chromatogr B Analyt Technol Biomed Life Sci. 1187: 123013. PMID: 34808577
  6. Multiresidues Multiclass Analytical Methods for Determination of Antibiotics in Animal Origin Food: A Critical Analysis.  |  Barros, SC., et al. 2023. Antibiotics (Basel). 12: PMID: 36830113
  7. Screening of antibiotic residues in raw bovine milk in Lombardy, Italy: Microbial growth inhibition assay and LC-HRMS technique integration for an accurate monitoring.  |  Butovskaya, E., et al. 2023. Heliyon. 9: e15395. PMID: 37123980

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Spiramycin I-d3, 1 mg

sc-220130
1 mg
$430.00