Date published: 2025-9-6
访问圣克鲁斯动物健康

021-6093-6350

SCBT Portrait Logo
Seach Input
联系我们
登陆账户
快速订购
购物车 (0)
spectrin α II Antibody (C-3) - Immunohistochemistry - Image 156761
spectrin a II (C-3): sc-48382. 对福尔马林固定, 石蜡包埋的人肾组织进行免疫过氧化物酶染色, 显示肾小球和肾小管细胞的细胞质和细胞膜染色.
spectrin a II (C-3): sc-48382. 对福尔马林固定, 石蜡包埋的人肾组织进行免疫过氧化物酶染色, 显示肾小球和肾小管细胞的细胞质和细胞膜染色.

spectrin α II 抗体 (C-3): sc-48382

4.8(13)
寫評論提問

说明书
  • spectrin alpha II 抗体 C-3 是小鼠单克隆 IgG1 κ，spectrin α II抗体, 在42篇文献中引用，规格为200 µg/ml
  • 免疫human物种的spectrin α II的氨基酸2368-2472
  • spectrin alpha II 抗体 (C-3) 推荐用于 WB, IP, IF, IHC(P) 和 ELISA，检测mouse, rat 和human 来源的 spectrin α II; 也和以下物种反应，包括： 和 canine, bovine and porcine
  • 抗spectrin alpha II抗体（C-3）可与琼脂糖结合用于IP；与HRP结合用于WB、IHC(P)和ELISA；与藻红蛋白或FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 和 Alexa Fluor® 647，用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统，例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680 和 Alexa Fluor® 790， 用于WB (NIR), IF 和 FCM; 以及用于近红外（NIR）检测系统，如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取spectrin α II (C-3): sc-48382的免费10 µg小样，联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP, m-IgG1 BP-HRP 和 m-IgGκ BP-HRP 是 spectrin α II 抗体 (C-3) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与spectrin α II 抗体 (C-3) 组合成套装提供。 (请参阅下面的订购信息)。

快捷链接

相关产品
描述
基因信息
说明书与实验方案
研究信息

関連項目

此外 spectrin 抗体 包括 spectrin α I, spectrin α II, spectrin β I, spectrin β II, spectrin β III和spectrin β IV

spectrin α II 抗体 (C-3) 是一种小鼠单克隆 IgG1 kappa 轻链抗体，可通过免疫印迹 (WB)、免疫沉淀 (IP)、免疫荧光 (IF)、石蜡包埋切片免疫组织化学 (IHCP) 和酶联免疫吸附试验 (ELISA) 检测小鼠、大鼠和人源的 spectrin α II 蛋白。spectrin α II 单克隆抗体（C-3）有非共轭型和多种共轭型，包括琼脂糖、辣根过氧化物酶（HRP）、藻红蛋白（PE）、异硫氰酸荧光素（FITC）和多种 Alexa Fluor® 共轭物。谱林 α II 又称 fodrin α，在非红细胞中对维持细胞骨架结构的完整性起着至关重要的作用，谱林 α II 主要位于细胞质中。谱林 α II 对细胞膜的组织和稳定至关重要，因为谱林 α II 形成的网状网络可支撑细胞形状并促进细胞内运输。谱林细胞骨架网络对各种细胞过程至关重要，包括细胞信号传递、运动和维持细胞的机械特性。谱林 α II 与其他细胞骨架蛋白（如肌动蛋白和各种膜蛋白）相互作用，形成一个动态的、适应性强的结构，以满足细胞的需要。钙蛋白酶活化分解谱蛋白 α II 可导致细胞结构发生重大改变，从而突出了谱蛋白 α II 在维持细胞稳态和功能方面的重要性。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

spectrin α II 抗体 (C-3) 参考文献:

  1. 急性神经元细胞死亡会选择性释放钙蛋白酶产生的 alphaalI-spectrin（alpha-fodrin）分解产物。  |  Dutta, S., et al. 2002. Biol Chem. 383: 785-91. PMID: 12108543
  2. Spectrin alpha II和beta II异构体在四聚体化位点具有高亲和力相互作用。  |  Bignone, PA. and Baines, AJ. 2003. Biochem J. 374: 613-24. PMID: 12820899
  3. 在大鼠发育过程中，alpha II-spectrin心脏选择性可变剪接变体cardi+的表征和表达。  |  Zhang, Y., et al. 2010. J Mol Cell Cardiol. 48: 1050-9. PMID: 20114050
  4. 光谱蛋白同工酶的功能多样性。  |  Coleman, TR., et al. 1989. Cell Motil Cytoskeleton. 12: 225-47. PMID: 2655937
  5. 光谱蛋白网络是红细胞横向扩散的障碍。渗滤分析  |  Saxton, MJ. 1989. Biophys J. 55: 21-8. PMID: 2930822
  6. 非红细胞α-谱蛋白基因的比较揭示了不同物种之间严格的同源性。  |  Leto, TL., et al. 1988. Mol Cell Biol. 8: 1-9. PMID: 3336352
  7. 红细胞谱蛋白结构的现状：106 个残基的重复结构是整类蛋白质的基本特征。  |  Speicher, DW. 1986. J Cell Biochem. 30: 245-58. PMID: 3517024
  8. 红细胞添加素对谱蛋白-肌动蛋白组装的调节。  |  Gardner, K. and Bennett, V. Nature. 328: 359-62. PMID: 3600811
  9. Spna2 R1098Q小鼠变体的进行性共济失调、记忆障碍和癫痫发作影响αII 斯普林蛋白的支架稳定性。  |  Zalas, M., et al. 2023. Brain Sci. 13: PMID: 36831804
  10. Erk 抑制是治疗高 IL-8 分泌和低 SPTAN1 表达结直肠癌的有效策略。  |  Meier, C., et al. 2024. Int J Mol Sci. 25: PMID: 38891846
  11. 遗传性椭圆细胞症中的异常spectrin。  |  Marchesi, SL., et al. 1986. Blood. 67: 141-51. PMID: 3940543
  12. 部分结构重复构成了所有 beta-spectrins的异二聚体自结合位点。  |  Kennedy, SP., et al. 1994. J Biol Chem. 269: 11400-8. PMID: 8157672

订购信息

产品名称产品编号规格价格数量收藏夹

spectrin α II 抗体 (C-3)

sc-48382
200 µg/ml
$316.00

spectrin α II (C-3): m-IgG Fc BP-HRP 套装

sc-528535
200 µg Ab; 10 µg BP
$354.00

spectrin α II (C-3): m-IgGκ BP-HRP 套装

sc-520932
200 µg Ab, 40 µg BP
$354.00

spectrin α II (C-3): m-IgG1 BP-HRP 套装

sc-542981
200 µg Ab; 20 µg BP
$354.00

spectrin α II 抗体 (C-3) AC

sc-48382 AC
500 µg/ml, 25% agarose
$416.00

spectrin α II 抗体 (C-3) HRP

sc-48382 HRP
200 µg/ml
$316.00

spectrin α II 抗体 (C-3) FITC

sc-48382 FITC
200 µg/ml
$330.00

spectrin α II 抗体 (C-3) PE

sc-48382 PE
200 µg/ml
$343.00

spectrin α II 抗体 (C-3) Alexa Fluor® 488

sc-48382 AF488
200 µg/ml
$357.00

spectrin α II 抗体 (C-3) Alexa Fluor® 546

sc-48382 AF546
200 µg/ml
$357.00

spectrin α II 抗体 (C-3) Alexa Fluor® 594

sc-48382 AF594
200 µg/ml
$357.00

spectrin α II 抗体 (C-3) Alexa Fluor® 647

sc-48382 AF647
200 µg/ml
$357.00

spectrin α II 抗体 (C-3) Alexa Fluor® 680

sc-48382 AF680
200 µg/ml
$357.00

spectrin α II 抗体 (C-3) Alexa Fluor® 790

sc-48382 AF790
200 µg/ml
$357.00

Can spectrin α II (C-3): sc-48382 monoclonal antibody be used for detection of NOS1 of monkey origin?

Asked by: jenni
Thank you for your inquiry. Please contact our Technical Service Department and we would be happy to perform sequence analysis and review our data to answer any questions you may have about additional species reactivity. We are available by phone, e-mail or chat.
Answered by: Technical Support 13
Date published: 2017-01-20

How can spectrin α II (C-3): sc-48382 mouse monoclonal antibody be used for double or triple staining, if the other primary antibodies are also raised in mouse?

Asked by: jenni
In this case, we recommend using a directly conjugated mouse monoclonal primary antibody. spectrin α II (C-3): sc-48382 monoclonal antibody is currently available conjugated to phycoerythrin (sc-48382 PE), fluorescein (sc-48382 FITC), Alexa Fluor® 488 (sc-48382 AF488) or Alexa Fluor® 647 (sc-48382 AF647)
Answered by: Technical Support 13
Date published: 2017-01-16
  • y_2025, m_8, d_28, h_5CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_2
  • loc_zh_CN, sid_48382, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getContent, 80ms
  • QUESTIONS, PRODUCT
Rated 5 out of 5 by from Excellent antibody for WB and ICCUsed the antibody for detection of Spectrin and Spectrin breakdown products in Sh-SY5Y cells.
Date published: 2018-07-27
Rated 4 out of 5 by from GreatWe tested in rat brains samples and mice heart. It works great!
Date published: 2018-05-24
Rated 4 out of 5 by from Clear bands in WBAntibody produces clear bands when used 1/1000 for 20ug of lymphoblast whole lysate on Western blot
Date published: 2018-02-12
Rated 4 out of 5 by from confirmed for IHCI tested this antibody for IHC (frozen sections). It worked well for me at 1:200 dilution overnight.
Date published: 2017-11-12
Rated 5 out of 5 by from works great on western blot and IHCWe have used this antibody on human skin tissue. It works great on both western blot and IHC.
Date published: 2017-09-20
Rated 5 out of 5 by from Outstanding product !!Very strong western blot data; also great IHC and IF data
Date published: 2017-01-26
Rated 5 out of 5 by from Good choice for IHC(P)This is a strong and specific antibody that'll give you beautiful IHC staining on paraffin tissue sections. Highly recommend it for your spectrin alpha II experiments.
Date published: 2017-01-16
Rated 5 out of 5 by from Robust signal in WB in HS68 and TFRobust signal in WB in HS68 and TF-1 whole cell lysates, mouse uterus and rat brain tissue extracts. -SCBT QC
Date published: 2015-06-09
  • y_2025, m_8, d_28, h_5
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_13
  • loc_zh_CN, sid_48382, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getReviews, 8ms
  • REVIEWS, PRODUCT
spectrin α II 抗体 (C-3) is rated 4.8 out of 5 by 13.
  • y_2025, m_8, d_28, h_5
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_13
  • loc_zh_CN, sid_48382, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 95ms
  • REVIEWS, PRODUCT
021-6093-6350
访问 Santa Cruz Animal Health|访问 San Juan Ranch
Santa Cruz Biotechnology, Inc. 是生物医学研究市场产品开发的世界领导者。请拨打0086-021-60936350联系我们。
版权所有© 2007-2025 Santa Cruz Biotechnology, Inc. 保留所有权利。”Santa Cruz Biotechnology” 和Santa Cruz Biotechnology, Inc.的商标，”Santa Cruz Animal Health”, “San Juan Ranch”, “Supplement of Champions”, San Juan Ranch的商标，”UltraCruz”, “ChemCruz”, “ImmunoCruz”, “ExactaCruz”, 和 “EZ Touch”是Santa Cruz Biotechnology, Inc.的注册商标。所有商标均为其各自所有者的财产。