Date published: 2025-9-7

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SP-B 抗体 (1B9): sc-53137

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说明书
  • SP-B抗体(1B9)是小鼠单克隆IgG2a κ, 在3篇文献中引用,规格为200 µg/ml
  • 针对全长SP-B,human起源
  • 抗-SP-B 抗体 (1B9) 推荐用于 WB, IP 和 ELISA,检测mouse, rat 和human 来源的 SP-B
  • 抗SP-B抗体(1B9)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取SP-B (1B9): sc-53137免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP是SP-B Antibody (1B9) 适用于 WB 应用。 的首选辅助检测试剂。该试剂现与SP-B Antibody (1B9) 搭配使用(请参阅下面的订购信息)。

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関連項目

SP-B抗体(1B9)是一种小鼠单克隆IgG2a kappa轻链抗体,可通过蛋白质印迹(WB)、免疫沉淀(IP)和酶联免疫吸附测定(ELISA)等方法检测小鼠、大鼠和人类样本中的SP-B。SP-B (1B9) 抗体有非结合型和多种结合型,包括琼脂糖、辣根过氧化物酶 (HRP)、藻红蛋白 (PE)、异硫氰酸荧光素 (FITC) 和多种 Alexa Fluor® 结合物,可满足不同实验需求。SP-B(表面活性蛋白B)在呼吸系统中起着至关重要的作用,它能够促进肺表面活性物的正常功能,而肺表面活性物对于降低肺泡中气液界面的表面张力至关重要。降低表面张力对于防止呼气时肺泡塌陷和确保有效的气体交换至关重要。SP-B的结构作为疏水性蛋白与表面活性脂相互作用,促进其吸收和稳定,因此尤为重要。SP-B能够形成低聚物,从而增强表面活性物质代谢和稳态功能,因此SP-B在维持肺功能和防止呼吸窘迫方面发挥着关键作用。SP-B的存在对于正常的呼吸生理至关重要,而功能障碍会导致严重的肺部疾病,这凸显了在各种研究和临床背景下研究SP-B的重要性。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

SP-B 抗体 (1B9) 参考文献:

  1. 肺表面活性蛋白SP-B和类皂素蛋白家族的结构-功能关系。  |  Olmeda, B., et al. 2013. Eur Biophys J. 42: 209-22. PMID: 22996193
  2. 表面活性蛋白B:从生物化学到其在心力衰竭中作为诊断和预后标志物的潜在作用。  |  Banfi, C. and Agostoni, P. 2016. Int J Cardiol. 221: 456-62. PMID: 27414721
  3. 肺表面活性蛋白SP-B纳米环诱导表面活性复合物的多层组织。  |  Martinez-Calle, M., et al. 2020. Biochim Biophys Acta Biomembr. 1862: 183216. PMID: 32067963
  4. 疏水表面活性蛋白SP-B和SP-C在流体双分子层中的位置。  |  Loney, RW., et al. 2020. J Phys Chem B. 124: 6763-6774. PMID: 32600036
  5. 表面活性蛋白B通过采用类似病毒的作用机制促进胞浆siRNA的传递。  |  Guagliardo, R., et al. 2021. ACS Nano. 15: 8095-8109. PMID: 33724778
  6. 肥胖哮喘患者表面活性蛋白B的下调。  |  Cao, TBT., et al. 2022. Clin Exp Allergy. 52: 1321-1329. PMID: 35294785
  7. 肺表面活性蛋白单层中的表面活性蛋白SP-B和SP-C:由特定蛋白质-脂质相互作用控制的物理性质。  |  Liekkinen, J., et al. 2023. Langmuir. 39: 4338-4350. PMID: 36917773
  8. 肺表面活性蛋白B肽与人ACE2受体的相互作用。  |  Waring, AJ., et al. 2023. Int J Mol Sci. 24: PMID: 37446012
  9. 评估新型SP-B和SP-C合成类似物的肺表面活性剂功效。  |  Kim, CY., et al. 2024. Int J Med Sci. 21: 775-783. PMID: 38617013
  10. 检查点阻断期间,表面活性蛋白B的自身免疫与肺炎有关。  |  Wyss, N., et al. 2024. Am J Respir Crit Care Med. 210: 919-930. PMID: 38626354

订购信息

产品名称产品编号规格价格数量收藏夹

SP-B 抗体 (1B9)

sc-53137
200 µg/ml
$316.00

SP-B (1B9): m-IgG Fc BP-HRP 套装

sc-525578
200 µg Ab; 10 µg BP
$354.00

SP-B 抗体 (1B9) AC

sc-53137 AC
500 µg/ml, 25% agarose
$416.00

SP-B 抗体 (1B9) HRP

sc-53137 HRP
200 µg/ml
$316.00

SP-B 抗体 (1B9) FITC

sc-53137 FITC
200 µg/ml
$330.00

SP-B 抗体 (1B9) PE

sc-53137 PE
200 µg/ml
$343.00

SP-B 抗体 (1B9) Alexa Fluor® 488

sc-53137 AF488
200 µg/ml
$357.00

SP-B 抗体 (1B9) Alexa Fluor® 546

sc-53137 AF546
200 µg/ml
$357.00

SP-B 抗体 (1B9) Alexa Fluor® 594

sc-53137 AF594
200 µg/ml
$357.00

SP-B 抗体 (1B9) Alexa Fluor® 647

sc-53137 AF647
200 µg/ml
$357.00

SP-B 抗体 (1B9) Alexa Fluor® 680

sc-53137 AF680
200 µg/ml
$357.00

SP-B 抗体 (1B9) Alexa Fluor® 790

sc-53137 AF790
200 µg/ml
$357.00

I need to biotinylate this antibody for the IP experiment in human plasma/serum, could you let me know the composition of buffer used in this product, i.e. what is with this antibody when you ship it to me. What is the volume per order ?

Asked by: Hong Wang
Thank you for your question. This information is available on our product data sheet that can be downloaded using the link below. For this antibody, we provide 200 µg of IgG in 1 mL of 1X PBS with < 0.1% sodium azide and 0.1% gelatin. https://datasheets.scbt.com/sc-53137.pdf
Answered by: Technical Support
Date published: 2017-10-02

I need to use an antibody to detect the protein in samples of monkey origin. Do you know if sc-53137: SP-B (1B9) mouse monoclonal antibody will work?

Asked by: Germaine
Please contact our Technical Service Department and we would be happy to perform sequence analysis and review our data to answer any questions you may have about additional species reactivity.
Answered by: Technical Support
Date published: 2017-03-06
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Rated 4 out of 5 by from Robust band seen in WB using human lung tissueRobust band seen in WB using human lung tissue extract. -SCBT QC
Date published: 2015-05-06
Rated 4 out of 5 by from Strong bands seen in WB using SPStrong bands seen in WB using SP-B expression (oligomers) in human lavage fluid. -SCBT QC
Date published: 2015-04-08
Rated 4 out of 5 by from Various publishable data in WB using humanVarious publishable data in WB using human transfected SaOS2 and lung cell lines. -SCBT Publication Review
Date published: 2015-01-20
Rated 4 out of 5 by from Publishable data in IF using human transfectedPublishable data in IF using human transfected SaOS2 cell lines. -SCBT Publication Review
Date published: 2013-12-22
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SP-B 抗体 (1B9) is rated 4.0 out of 5 by 4.
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