Date published: 2025-9-6

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Sox-4 抗体 (B-7): sc-518016

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说明书
  • Sox-4抗体(B-7)是小鼠单克隆IgG1 κ, 在8篇文献中引用,规格为200 µg/ml
  • 免疫human来源Sox-4内部区域的281-370氨基酸
  • 抗-Sox-4 抗体 (B-7) 推荐用于 WB, IP, IF 和 ELISA,检测mouse, rat 和human 来源的 Sox-4
  • 抗Sox-4抗体(B-7)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 可用于凝胶迁移和ChIP的TransCruz试剂(sc-518016 X, 200 µg/0.1 ml)
  • 关于如何获取Sox-4 (B-7): sc-518016免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP1 BP-HRP">m-IgG1 BP-HRPm-IgGκ BP-HRP是Sox-4 Antibody (B-7) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与Sox-4 Antibody (B-7) 打包提供(请参阅下面的订购信息)。

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関連項目

Sox-4抗体(B-7)是一种小鼠单克隆IgG1 kappa轻链抗体,可通过应用诸如蛋白质印迹(WB)、免疫沉淀(IP)、免疫荧光(IF)和酶联免疫吸附测定(ELISA)等方法检测小鼠、大鼠和人类样本中的Sox-4。Sox-4 (B-7) 抗体有非结合型和多种结合型,包括琼脂糖、辣根过氧化物酶 (HRP)、藻红蛋白 (PE)、异硫氰酸荧光素 (FITC) 和多种 Alexa Fluor® 结合物。Sox-4在发育过程中调节基因表达方面发挥着至关重要的作用,尤其是在各种细胞类型的分化过程中。Sox-4是一种转录因子,可与特定的DNA序列结合,影响细胞命运决定和发育过程中目标基因的转录。Sox-4调节这些途径的能力对于胚胎的正常发育和组织稳态至关重要,而Sox-4失调与多种人类疾病有关,包括某些癌症和发育障碍。Sox-4基因在进化过程中的保存凸显了其在发育生物学中的重要性,使Sox-4成为基础和应用科学研究的重大目标。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Sox-4 参考文献:

  1. SOX4是人体癌症的潜在预后因子:系统评价和荟萃分析。  |  Chen, J., et al. 2016. Clin Transl Oncol. 18: 65-72. PMID: 26250764
  2. 肿瘤相关巨噬细胞产生的CXCL1通过激活NF-κB/SOX4信号传导促进乳腺癌转移。  |  Wang, N., et al. 2018. Cell Death Dis. 9: 880. PMID: 30158589
  3. 癌相关成纤维细胞通过SOX4/MMP11信号轴驱动早期胰腺癌细胞侵袭。  |  Ge, F., et al. 2024. Biochim Biophys Acta Mol Basis Dis. 1870: 166852. PMID: 37633471
  4. LINC00926通过调节miR-30a-5p/SOX4轴并激活IFNγ-JAK2-STAT1通路促进肾细胞癌的进展。  |  Du, L., et al. 2023. Cancer Lett. 578: 216463. PMID: 37866544
  5. SOX4/EZH2/SLC7A11信号轴介导草酸钙晶体沉积引起的肾损伤中的铁死亡。  |  Yan, X., et al. 2024. J Transl Med. 22: 9. PMID: 38169402
  6. METTL3介导的SOX4的m6A修饰通过YTHDF3识别调节成骨细胞的增殖和分化。  |  Feng, ZW., et al. 2024. Cell Signal. 115: 111038. PMID: 38195035
  7. SOX4先导因子活性的体内细胞重编程。  |  Katsuda, T., et al. 2024. Nat Commun. 15: 1761. PMID: 38409161
  8. 靶向SOX4/PCK2信号通路可抑制去势抵抗性前列腺癌的神经内分泌转分化。  |  Jing, N., et al. 2024. Biol Direct. 19: 56. PMID: 39014441
  9. SOX4通过小鼠EBF2介导的产热基因程序促进棕色脂肪的发育和维持。  |  Wang, S., et al. 2024. Cell Death Differ.. PMID: 39402212
  10. Sox-4促进胸腺细胞分化。  |  Schilham, MW., et al. 1997. Eur J Immunol. 27: 1292-5. PMID: 9174623

订购信息

产品名称产品编号规格价格数量收藏夹

Sox-4 抗体 (B-7)

sc-518016
200 µg/ml
$316.00

Sox-4 (B-7): m-IgG Fc BP-HRP 套装

sc-531594
200 µg Ab; 10 µg BP
$354.00

Sox-4 (B-7): m-IgGκ BP-HRP 套装

sc-525326
200 µg Ab, 40 µg BP
$354.00

Sox-4 (B-7): m-IgG1 BP-HRP 套装

sc-544647
200 µg Ab; 20 µg BP
$354.00

Sox-4 抗体 (B-7) X

sc-518016 X
200 µg/0.1 ml
$316.00

Sox-4 抗体 (B-7) AC

sc-518016 AC
500 µg/ml, 25% agarose
$416.00

Sox-4 抗体 (B-7) HRP

sc-518016 HRP
200 µg/ml
$316.00

Sox-4 抗体 (B-7) FITC

sc-518016 FITC
200 µg/ml
$330.00

Sox-4 抗体 (B-7) PE

sc-518016 PE
200 µg/ml
$343.00

Sox-4 抗体 (B-7) Alexa Fluor® 488

sc-518016 AF488
200 µg/ml
$357.00

Sox-4 抗体 (B-7) Alexa Fluor® 546

sc-518016 AF546
200 µg/ml
$357.00

Sox-4 抗体 (B-7) Alexa Fluor® 594

sc-518016 AF594
200 µg/ml
$357.00

Sox-4 抗体 (B-7) Alexa Fluor® 647

sc-518016 AF647
200 µg/ml
$357.00

Sox-4 抗体 (B-7) Alexa Fluor® 680

sc-518016 AF680
200 µg/ml
$357.00

Sox-4 抗体 (B-7) Alexa Fluor® 790

sc-518016 AF790
200 µg/ml
$357.00

Thank you for your quick response. Can I apply for the 10ug small test for SOX4 PE?

Asked by: Qiao Lyle
Thank you for your question. It would be helpful if you could call us directly at (021) 800-820-8626, allowing for a more interactive discussion of this and other related questions.
Answered by: Santa Cruz TS
Date published: 2021-08-03

Sox-4 抗体 (B-7) PE sc-518016 PE 200 µg/ml RMB2,407.00  Dose this mean that the sox4 antibody has conjugated with the PE? 

Asked by: Qiao Lyle
Thank you for your question. Yes, this refers to the PE conjugated variant of the antibody.
Answered by: Tech Support Europe
Date published: 2021-08-02
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Rated 5 out of 5 by from Antibody shows great specificity with human Sox-4Antibody works well with a transfected lysate that over-expresses human SOX4. Transfected Lysate's NCBI Reference Sequence: 003107.3 -SCBT QC
Date published: 2023-09-14
Rated 4 out of 5 by from Work well for WBGot a 10ug sample of this antibody along with my last order of other SC antibody. This SOX4 ab worked well and showed a specific band with SOX4-transfected cells on WB blot. Also tried IHC staining by this ab, but seemed not to work on FFPE samples.
Date published: 2018-01-03
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Sox-4 抗体 (B-7) is rated 4.5 out of 5 by 2.
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