Date published: 2025-9-6

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SCCA1 抗体 (8H11): sc-21767

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说明书
  • SCCA1 抗体 8H11 是小鼠单克隆 IgG1 κ,SCCA1抗体, 在13篇文献中引用,规格为200 µg/ml
  • 针对重组human SCCA1
  • SCCA1 抗体 (8H11) 推荐用于WB, IP, IF 和 IHC(P),检测human 来源的 SCCA1
  • SCCA1抗体(8H11)可与琼脂糖结合用于IP,与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 可用于凝胶迁移和ChIP的TransCruz试剂(sc-21767 X, 200 µg/0.1 ml)
  • 关于如何获取SCCA1 (8H11): sc-21767免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRPm-IgG1 BP-HRP 是 SCCA1 抗体 (8H11) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与SCCA1 抗体 (8H11) 组合成套装提供。 (请参阅下面的订购信息)。

快捷链接

関連項目

SCCA1抗体(8H11)是一种小鼠单克隆IgG1 kappa轻链抗体,可通过蛋白质印迹(WB)、免疫沉淀(IP)、免疫荧光(IF)和免疫组织化学检测人类来源的SCCA1蛋白。SCCA1 (8H11) 抗体有非结合型和多种结合型,包括琼脂糖、藻红蛋白(PE)、异硫氰酸荧光素(FITC)和多种 Alexa Fluor® 结合型。SCCA1 是血清蛋白抑制剂家族的一员,在调节丝氨酸蛋白酶方面发挥着关键作用,丝氨酸蛋白酶是一种可通过降解细胞外基质成分促进肿瘤转移的酶。这种调节至关重要,因为它有助于维持蛋白水解活性与组织完整性之间的平衡,从而影响癌症的进展。SCCA1基因位于人类18号染色体21.3区,主要表达为SCCA1,与多种癌症类型有关,包括宫颈癌、肺癌、食道癌和头颈癌,其中SCCA1水平随着疾病进展而增加。SCCA1由390个氨基酸组成,首次在转移性宫颈癌鳞状细胞癌中发现,这凸显了SCCA1作为癌症诊断和预后生物标志物的意义。抗SCCA1抗体(8H11)是研究人员研究癌症转移机制和血清蛋白在肿瘤生物学中的作用的重要工具。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

SCCA1 抗体 (8H11) 参考文献:

  1. 外阴上皮内瘤变和外阴癌患者血清中鳞状细胞癌抗原的浓度。  |  Hefler, L., et al. 1999. Int J Cancer. 84: 299-303. PMID: 10371350
  2. 从上颌窦癌中分离出高分泌 SCC 抗原和 CEA 的腺样鳞癌细胞并确定其特征。  |  Kishimoto, H., et al. 2000. Oral Oncol. 36: 70-5. PMID: 10889923
  3. 鳞状细胞癌(SCC)抗原对宫颈癌患者放疗后随访的影响。  |  Micke, O., et al. 2000. Anticancer Res. 20: 5113-5. PMID: 11326679
  4. 癌细胞外周 T 淋巴细胞中 SCCA1 的表达与舌鳞癌患者血清 SCC 抗原的升高有关。  |  Yasumatsu, R., et al. 2001. Cancer Lett. 167: 205-13. PMID: 11369142
  5. 替代剪接产生的新型鳞状细胞癌抗原转录本。  |  Suminami, Y., et al. 2001. Biochim Biophys Acta. 1519: 122-6. PMID: 11406281
  6. 人类宫颈鳞状细胞癌肿瘤抗原的放射免疫测定。  |  Kato, H. and Torigoe, T. 1977. Cancer. 40: 1621-8. PMID: 332328

订购信息

产品名称产品编号规格价格数量收藏夹

SCCA1 抗体 (8H11)

sc-21767
200 µg/ml
$316.00

SCCA1 (8H11): m-IgG Fc BP-HRP 套装

sc-526614
200 µg Ab; 10 µg BP
$354.00

SCCA1 (8H11): m-IgG1 BP-HRP 套装

sc-531987
200 µg Ab; 20 µg BP
$354.00

SCCA1 抗体 (8H11) X

sc-21767 X
200 µg/0.1 ml
$316.00

SCCA1 抗体 (8H11) AC

sc-21767 AC
500 µg/ml, 25% agarose
$416.00

SCCA1 抗体 (8H11) FITC

sc-21767 FITC
200 µg/ml
$330.00

SCCA1 抗体 (8H11) PE

sc-21767 PE
200 µg/ml
$343.00

SCCA1 抗体 (8H11) Alexa Fluor® 488

sc-21767 AF488
200 µg/ml
$357.00

SCCA1 抗体 (8H11) Alexa Fluor® 546

sc-21767 AF546
200 µg/ml
$357.00

SCCA1 抗体 (8H11) Alexa Fluor® 594

sc-21767 AF594
200 µg/ml
$357.00

SCCA1 抗体 (8H11) Alexa Fluor® 647

sc-21767 AF647
200 µg/ml
$357.00

SCCA1 抗体 (8H11) Alexa Fluor® 680

sc-21767 AF680
200 µg/ml
$357.00

SCCA1 抗体 (8H11) Alexa Fluor® 790

sc-21767 AF790
200 µg/ml
$357.00

What is the recommended secondary for use with this mouse monoclonal primary antibody?

Asked by: AbPolly
Thank you for your question. We recommend using one our exclusive Mouse IgG Binding Proteins as a secondary detection reagent. A complete list of available binding proteins is available on our website here: https://www.scbt.com/scbt/browse/support-products-mouse-igg-binding-proteins/_/N-ecrety
Answered by: Technical Support 2
Date published: 2017-01-24
  • y_2025, m_8, d_28, h_5CST
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Rated 5 out of 5 by from Good for WB and IHCSCCA1 Antibody (8H11) is a good choice for WB and IHC(P) as indicated by recent journal publications.
Date published: 2017-01-05
Rated 4 out of 5 by from Used this antibody in WB and got correct bandUsed this antibody in WB and got correct band.
Date published: 2015-08-26
Rated 5 out of 5 by from This antibody was used in a publication forThis antibody was used in a publication for WB on human esophageal squamous cell carcinoma - SCBT Publication Review
Date published: 2015-05-18
Rated 5 out of 5 by from Successful application of this antibody inSuccessful application of this antibody in WB using human saliva from patient with OSCC ulcerative lesions located on the tongue -SCBT Publication Review
Date published: 2015-05-06
Rated 5 out of 5 by from Publishable IHCP and WB data with human 293TPublishable IHCP and WB data with human 293T cells - SCBT Publication Review
Date published: 2015-02-14
Rated 5 out of 5 by from IHC publishable data with human normal peripheralIHC publishable data with human normal peripheral blood mononuclear cells and vulvar squamous cell - SCBT Publication Review
Date published: 2014-01-22
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SCCA1 抗体 (8H11) is rated 4.8 out of 5 by 6.
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