Date published: 2025-9-6
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S-100A10 Antibody (4E7E10) - Western Blotting - Image 362355
S-100A10 抗体 (4E7E10): sc-81153. A-431 (A), MCF7 (B) 和 Caco-2 (C) 全细胞裂解液中 S-100A10 表达的 Western 印迹分析.
S-100A10 抗体 (4E7E10): sc-81153. A-431 (A), MCF7 (B) 和 Caco-2 (C) 全细胞裂解液中 S-100A10 表达的 Western 印迹分析.

S-100A10 抗体 (4E7E10): sc-81153

3.5(6)
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说明书
  • S-100A10 抗体 4E7E10 是小鼠单克隆 IgG1 κ，S-100A10抗体, 在11篇文献中引用，规格为200 µg/ml
  • 与重组蛋白结合，该重组蛋白与S-100A10的2-97的氨基酸对应，来源于human
  • S-100A10 抗体 (4E7E10) 推荐用于WB, IP, IF, IHC(P) 和 FCM，检测human 来源的 S-100A10
  • 抗S-100A10抗体（4E7E10）可与琼脂糖结合用于IP；与HRP结合用于WB、IHC(P)和ELISA；与藻红蛋白或FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 和 Alexa Fluor® 647，用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统，例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680 和 Alexa Fluor® 790， 用于WB (NIR), IF 和 FCM; 以及用于近红外（NIR）检测系统，如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取S-100A10 (4E7E10): sc-81153的免费10 µg小样，联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgGκ BP-HRP 是 S-100A10 抗体 (4E7E10) 在 WB and IHC(P) 应用中的首选二抗检测试剂。该试剂现与S-100A10 抗体 (4E7E10) 组合成套装提供。 (请参阅下面的订购信息)。其他m-IgGκ BP 偶联产品，请参阅我们的小鼠 IgG 结合蛋白完整列表。

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描述
基因信息
说明书与实验方案
研究信息

関連項目

此外 S-100 抗体包括 S-100 α chain, S-100 β chain, S-100A10, S-100A13, S-100A14, S-100A16, S-100A2, S-100A3 和 S-100P

S-100A10抗体（4E7E10）是一种小鼠单克隆IgG1 kappa轻链抗体，可通过蛋白质印迹（WB）、免疫沉淀（IP）、免疫荧光（IF）、石蜡包埋切片免疫组织化学（IHCP）和流式细胞术（FCM）检测人源S-100A10蛋白。抗S-100A10抗体（4E7E10）有非结合型和多种结合型，包括琼脂糖、辣根过氧化物酶（HRP）、藻红蛋白（PE）、异硫氰酸荧光素（FITC）和多种Alexa Fluor®结合物。S-100A10，也称为细胞内附蛋白II的细胞配体，通过与各种靶蛋白相互作用，在调节生物信号通路中起着至关重要的作用。S-100A10参与与癌细胞细胞外表面上的附蛋白II形成异四聚体复合物，这对纤溶酶原激活具有重要意义，尽管这种相互作用对于定位或功能并非必不可少。S-100A10 还可以作为乙型肝炎病毒聚合酶的细胞伴侣，促进其从细胞质向细胞核的转移，从而表明 S-100A10 与病毒复制有关。这种独特的功能凸显了 S-100A10 在癌症生物学和病毒发病机理中的重要性，使 S-100A10 (4E7E10) 单克隆抗体成为研究这些关键领域的宝贵工具。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

S-100A10 抗体 (4E7E10) 参考文献:

  1. 精神分裂症患者 S100-beta 蛋白减少：初步证据。  |  Gattaz, WF., et al. 2000. Schizophr Res. 43: 91-5. PMID: 10858627
  2. S100A7, S100A10 和 S100A11 是转谷氨酰胺酶的底物。  |  Ruse, M., et al. 2001. Biochemistry. 40: 3167-73. PMID: 11258932
  3. 胃癌过度表达 S100A 钙结合蛋白。  |  El-Rifai, W., et al. 2002. Cancer Res. 62: 6823-6. PMID: 12460893
  4. 豚鼠平滑肌中 S100 Ca2+ 结合蛋白家族成员的表达。  |  Daub, B., et al. 2003. Cell Calcium. 33: 1-10. PMID: 12526882
  5. 表皮分化和牛皮癣过程中的 S100 蛋白亚细胞定位。  |  Broome, AM., et al. 2003. J Histochem Cytochem. 51: 675-85. PMID: 12704215
  6. 由 S100 家族蛋白 p11 介导的乙型肝炎病毒聚合酶与早幼粒细胞白血病核体的关联。  |  Choi, J., et al. 2003. Biochem Biophys Res Commun. 305: 1049-56. PMID: 12767936
  7. 人类p11钙蛋白I轻链的cDNA序列。  |  Dooley, TP., et al. 1992. Genomics. 13: 866-8. PMID: 1386341
  8. RNA 干扰介导的 S100A10 基因沉默可减少凝血酶的生成和 Colo 222 大肠癌细胞的侵袭性。  |  Zhang, L., et al. 2004. J Biol Chem. 279: 2053-62. PMID: 14570893
  9. 表皮中的 S100 蛋白。  |  Eckert, RL., et al. 2004. J Invest Dermatol. 123: 23-33. PMID: 15191538
  10. ANXA2/S100A10复合物对癌性纤溶酶原受体的调节。  |  Bharadwaj, AG., et al. 2021. Biomolecules. 11: PMID: 34944416
  11. S100A10通过转移细胞外囊泡并调节其蛋白质货物来促进肝癌的发展和进展。  |  Wang, X., et al. 2023. Gut. 72: 1370-1384. PMID: 36631249
  12. S100A10通过在肺部募集MDSC来促进癌症转移。  |  Li, J., et al. 2024. Oncoimmunology. 13: 2381803. PMID: 39071160

订购信息

产品名称产品编号规格价格数量收藏夹

S-100A10 抗体 (4E7E10)

sc-81153
200 µg/ml
$316.00

S-100A10 (4E7E10): m-IgGκ BP-HRP 套装

sc-521166
200 µg Ab, 40 µg BP
$354.00

S-100A10 抗体 (4E7E10) AC

sc-81153 AC
500 µg/ml, 25% agarose
$416.00

S-100A10 抗体 (4E7E10) HRP

sc-81153 HRP
200 µg/ml
$316.00

S-100A10 抗体 (4E7E10) FITC

sc-81153 FITC
200 µg/ml
$330.00

S-100A10 抗体 (4E7E10) PE

sc-81153 PE
200 µg/ml
$343.00

S-100A10 抗体 (4E7E10) Alexa Fluor® 488

sc-81153 AF488
200 µg/ml
$357.00

S-100A10 抗体 (4E7E10) Alexa Fluor® 546

sc-81153 AF546
200 µg/ml
$357.00

S-100A10 抗体 (4E7E10) Alexa Fluor® 594

sc-81153 AF594
200 µg/ml
$357.00

S-100A10 抗体 (4E7E10) Alexa Fluor® 647

sc-81153 AF647
200 µg/ml
$357.00

S-100A10 抗体 (4E7E10) Alexa Fluor® 680

sc-81153 AF680
200 µg/ml
$357.00

S-100A10 抗体 (4E7E10) Alexa Fluor® 790

sc-81153 AF790
200 µg/ml
$357.00

Can this antibody react with Rat tissue?

Asked by: Hongye
Thank you for your question. This antibody has not yet been tested in rat tissue, and so it is not a recommended species at this time.
Answered by: Technical Support
Date published: 2019-08-16

How can S-100A10 (4E7E10): sc-81153 mouse monoclonal antibody be used for double or triple staining, if the other primary antibodies are also raised in mouse?

Asked by: Professor Griffin
In this case, we recommend using a directly conjugated mouse monoclonal primary antibody. This antibody is available conjugated to phycoerythrin (sc-81153 PE) or fluoroscein (sc-81153 FITC).
Answered by: Technical Support
Date published: 2017-02-25
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Rated 4 out of 5 by from Good for Western blotI tested the antibody only for Western blot on samples derived from fractionation of cells in membranes, cytoplasm and nuclei by using a commercial kit. Antibody signal was enriched in the membranes fraction.
Date published: 2017-04-26
Rated 3 out of 5 by from 适用于western bloting检测适用于western bloting检测，但是检测效率不是很高；并且试着做了COIP的检测，也没有检测出来，可能实验条件需要再优化。
Date published: 2017-01-16
Rated 4 out of 5 by from Good and specific signal for S100A10I have used this antibody many times for detection of S100A10 by western blotting and immunofluorescence, it gives a good and specific signal for the target protein
Date published: 2016-11-24
Rated 4 out of 5 by from Good and specific signal for S100A10I have used this antibody for western blotting obtaining a very specific 11 KDa band with a good signal. I have used this antibody also for immunofluorescence and obtained a good cell membrane signal using several cancer cell lines
Date published: 2016-10-19
Rated 3 out of 5 by from Worked well with transfected lysate by WBWorked well with transfected lysate by WB -SCBT QC
Date published: 2015-04-10
Rated 3 out of 5 by from Good immunoperoxidase membrane and cytoplasmicGood immunoperoxidase membrane and cytoplasmic staining in formalin fixed, paraffin-embedded human prostate tissue. -SCBT QC
Date published: 2015-02-04
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S-100A10 抗体 (4E7E10) is rated 3.5 out of 5 by 6.
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