Date published: 2025-9-8

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RhCG 抗体 (CB-62): sc-100287

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说明书
  • RhCG 抗体 CB-62 是小鼠单克隆 IgG2a κ,RhCG抗体, 在2篇文献中引用,规格为100 µg/ml
  • 免疫human物种的重组RhCG
  • 推荐用于 mouse, rat 和 human 来源的RhCG WB, IP, IF, IHC(P) 和 ELISA检测
  • 关于如何获取RhCG (CB-62): sc-100287免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRPm-IgG2a BP-HRP 是 RhCG 抗体 (CB-62) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与RhCG 抗体 (CB-62) 组合成套装提供。 (请参阅下面的订购信息)。

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関連項目

RhCG抗体(CB-62)是一种IgG2a κ型小鼠单克隆RhCG抗体(也称为RhCG抗体),可通过蛋白质印迹(WB)、免疫沉淀(IP)、免疫荧光(IF)、免疫组织化学(IHC(P))和酶联免疫吸附测定(ELISA)检测小鼠、大鼠和人源的RhCG蛋白。RhCG抗体(CB-62)为非偶联的抗RhCG抗体。RhCG(Rhesus血型家族C型糖蛋白),也称为RHGK(Rh糖蛋白肾)、PDRC2(肿瘤相关蛋白DRC2)或SLC42A3,是一种具有三个潜在N-糖基化位点的多通道膜蛋白,属于铵转运蛋白家族的Rh亚家族。RhCG在多种组织中表达,主要在成人和胎儿肾脏中表达,定位于顶端和/或基底外侧细胞膜(取决于物种),被认为是一种非红细胞、双向、电中性铵转运蛋白。具体来说,RhCG存在于肾脏的各个部位,如连接段(CNT)、远曲小管(DCT)、集合管和初始集合管(ICT),这些是肾脏氨分泌的主要贡献者。这表明RhCG在肾脏氨代谢中发挥着重要作用。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

RhCG 抗体 (CB-62) 参考文献:

  1. 人类 RhCG 和小鼠 Rhcg 作为主要在肾脏和睾丸中表达的新型非红细胞 Rh 糖蛋白同源物的特征。  |  Liu, Z., et al. 2000. J Biol Chem. 275: 25641-51. PMID: 10852913
  2. 猕猴抗原的新面孔。  |  Heitman, J. and Agre, P. 2000. Nat Genet. 26: 258-9. PMID: 11062455
  3. 人类恒河猴相关 RhAG 蛋白和肾脏同源物促进酵母中的氨转运。  |  Marini, AM., et al. 2000. Nat Genet. 26: 341-4. PMID: 11062476
  4. Amt/MEP/Rh 的氨转运机制:1.35 A 时 AmtB 的结构。  |  Khademi, S., et al. 2004. Science. 305: 1587-94. PMID: 15361618
  5. 人类 Rh 蛋白三维结构的疏水簇分析和建模。  |  Callebaut, I., et al. 2006. Transfus Clin Biol. 13: 70-84. PMID: 16584906
  6. 正常和肿瘤性人类肾脏中氨转运体 rh C 糖蛋白的表达。  |  Han, KH., et al. 2006. J Am Soc Nephrol. 17: 2670-9. PMID: 16928804
  7. 肾脏质量下降对肾脏氨转运家族, Rh C 糖蛋白和 Rh B 糖蛋白表达的影响。  |  Kim, HY., et al. 2007. Am J Physiol Renal Physiol. 293: F1238-47. PMID: 17652373
  8. 结肠隐窝细胞系 T84 的氨转运:恒河猴糖蛋白和 NKCC1 的作用。  |  Worrell, RT., et al. 2008. Am J Physiol Gastrointest Liver Physiol. 294: G429-40. PMID: 18032481
  9. RHCG 通过抑制迁移和诱导受 TGF-β1 调控的细胞凋亡来抑制宫颈癌的进展。  |  Wang, DG., et al. 2018. Biochem Biophys Res Commun. 503: 86-93. PMID: 29852177
  10. 高RhCG表达预示着较差的生存率,并通过保持细胞内碱性促进胃癌的迁移和增殖。  |  Chen, P., et al. 2020. Exp Cell Res. 386: 111740. PMID: 31756312
  11. 醛固酮在肾脏中调节氨转运蛋白Rhcg。  |  Eguchi, K., et al. 2021. J Endocrinol. 249: 95-112. PMID: 33705345
  12. RHCG在子宫内膜癌中的表达和临床意义。  |  Wang, H., et al. 2024. Histol Histopathol. 39: 611-621. PMID: 37732703

订购信息

产品名称产品编号规格价格数量收藏夹

RhCG 抗体 (CB-62)

sc-100287
100 µg/ml
$333.00

RhCG (CB-62): m-IgG Fc BP-HRP 套装

sc-539680
100 µg Ab; 10 µg BP
$354.00

RhCG (CB-62): m-IgG2a BP-HRP 套装

sc-546749
100 µg Ab; 10 µg BP
$354.00

HI, I was wondering if a there's information on the epitope sequence for this antibody.?

Asked by: Mike27
Thank you for your question. The exact epitope recognized by this mouse monoclonal antibody, RhCG (CB-62): sc-100287, has not been determined. Please contact our Technical Service Department if you would like help performing sequence analysis against the antibody antigen to predict possible cross-reactivity with other species.
Answered by: Technical Support
Date published: 2017-10-25

Can sc-100287: RhCG (CB-62) monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

Asked by: AbPolly
Thank you for your question. Yes, sc-100287: RhCG (CB-62) is recommended for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Answered by: Technical Support
Date published: 2017-03-24
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Rated 5 out of 5 by from Good for Western BlotAntibody works for Western blot with alderosterone or arginine vasopressin treated IN-IC cell lysates in published research -SCBT QC
Date published: 2023-09-14
Rated 5 out of 5 by from WB publishable data with mouse and rat intercalatedWB publishable data with mouse and rat intercalated cells (IN-IC cells) and kidney - SCBT Publication Review
Date published: 2015-04-03
Rated 5 out of 5 by from Produced excellent immunoperoxidase membraneProduced excellent immunoperoxidase membrane staining in formalin-fixed, paraffin-embedded human salivary gland tissue. -SCBT QC
Date published: 2013-12-05
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RhCG 抗体 (CB-62) is rated 5.0 out of 5 by 3.
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