Date published: 2026-10-19
访问圣克鲁斯动物健康

1-800-457-3801

SCBT Portrait Logo
Seach Input
联系我们
登陆账户
快速订购
购物车 (0)
RelB Antibody (F-2) - Western Blotting - Image 352469
RelB 抗体 (F-2): sc-166417. Raji (A), HeLa (B) 和 Ramos (C) 全细胞裂解液中 RelB 表达的 Western 印迹分析.
RelB 抗体 (F-2): sc-166417. Raji (A), HeLa (B) 和 Ramos (C) 全细胞裂解液中 RelB 表达的 Western 印迹分析.

RelB 抗体 (F-2): sc-166417

4.0(3)
寫評論提問
说明书
  • RelB抗体(F-2)是小鼠单克隆IgG2a (kappa轻链)，规格为200 µg/ml
  • 特异性抗原位于mouse物种的RelB的C-terminus的氨基酸532-558之间
  • 推荐用于 mouse, rat 和 human 来源的RelB p68 WB, IP, IF 和 ELISA检测
  • 可用于ChIP的TransCruz试剂(sc-166417 X, 200 µg/0.1 ml)
  • 看 RelB (D-4): sc-48366，可查看有标记的 RelB 抗体，包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • 2a BP-HRP">m-IgG2a BP-HRP是RelB Antibody (F-2) 适用于 WB 应用。 的首选辅助检测试剂。该试剂现与RelB Antibody (F-2) 打包提供（请参阅下面的订购信息）。
    Gene Editing Promo Banner

    快捷链接

    相关产品
    描述
    基因信息
    说明书与实验方案
    研究信息

    関連項目

    NFκB转录因子最初被鉴定为由DNA结合亚基和相关蛋白组成的蛋白质复合物。DNA结合亚基在功能上与c-Rel p75和Rel B p68相关。p50亚基最初被认为是来自名为p105的前体氨基末端的功能独特的蛋白质。已经鉴定出第二种被命名为p52的蛋白质（以前称为p49），它可以作为替代的NFκB亚基。Rel B不以高亲和力与NFkB位点结合，但Rel B和p50之间的异二聚体与p50 NFκB同二聚体的亲和力相当。然而，与NFκB异二聚体相反，Rel B/p50异二聚体可反式激活含有κB结合位点的启动子的转录。

    仅限研究使用。不适用于诊断和治疗用途。

    Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

    LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

    RelB 抗体 (F-2) 参考文献:

    1. RelB调控前列腺癌细胞的锰超氧化物歧化酶基因和抗电离辐射能力  |  Holley, AK., et al. 2010. Ann N Y Acad Sci. 1201: 129-36. PMID: 20649549
    2. RelB/p50复合物调节细胞因子诱导的YKL-40表达。  |  Bhardwaj, R., et al. 2015. J Immunol. 194: 2862-70. PMID: 25681350
    3. RelB NF-κB亚基的翻译后修饰及相关功能。  |  Baud, V. and Collares, D. 2016. Cells. 5: PMID: 27153093
    4. RelB缺陷树突状细胞促进自发性过敏性气道炎症的发展。  |  Nair, PM., et al. 2018. Am J Respir Cell Mol Biol. 58: 352-365. PMID: 28960101
    5. RelB调节结膜CCL2的基底和促炎性诱导。  |  Seet, LF., et al. 2021. Ocul Immunol Inflamm. 29: 29-42. PMID: 31618101
    6. RelB抑制树突状细胞中的I型干扰素信号。  |  Saha, I., et al. 2020. Cell Immunol. 349: 104043. PMID: 32044112
    7. RelB调节稳态增殖，但不调节Treg的功能。  |  Zhou, S., et al. 2020. BMC Immunol. 21: 37. PMID: 32552667
    8. RelB 在体外通过外泌体 ICAM1 促进前列腺癌 DU145 细胞的迁移和侵袭。  |  Li, W., et al. 2022. Cell Signal. 91: 110221. PMID: 34933092
    9. 功能基因筛选确定 ITPR3/钙/RELB 轴是结直肠癌转移性肝定植的驱动因素。  |  Moy, RH., et al. 2022. Dev Cell. 57: 1146-1159.e7. PMID: 35487218
    10. 肠道中由RelB依赖性迁移树突状细胞强化的免疫耐受调节了保护性2型免疫。  |  Geiselhöringer, AL., et al. 2024. Nat Commun. 15: 9143. PMID: 39443450

    订购信息

    产品名称产品编号规格价格数量收藏夹

    RelB 抗体 (F-2)

    sc-166417
    200 µg/ml
    		$322.00

    RelB (F-2): m-IgG2a BP-HRP 套装

    sc-546029
    200 µg Ab; 10 µg BP
    		$361.00

    RelB (F-2) 中和勝肽

    sc-166417 P
    100 µg/0.5 ml
    		$69.00

    RelB 抗体 (F-2) X

    sc-166417 X
    200 µg/0.1 ml
    		$322.00

    What application is the blocking peptide sc-166417 P appropriate for?

    Asked by: Trav11
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Answered by: Technical Support
    Date published: 2017-02-24
    • y_2026, m_10, d_18, h_6CST
    • bvseo_bulk, prod_bvqa, vn_bulk_3.0.48
    • cp_1, bvpage1
    • co_hasquestionsanswers, tq_1
    • loc_zh_CN, sid_166417, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
    • clientName_scbt
    • bvseo_sdk, java_sdk, bvseo-4.0.0
    • CLOUD, getContent, 79ms
    • QUESTIONS, PRODUCT
    Rated 2 out of 5 by Sharmistha Pal from works in western but not ChIPI bought this antibody as an alternative to sc-226. Its not as great as sc226 for western but does detect the protein. Unlike sc-226 does not work for ChIP experiment.
    Date published: 2017-01-10
    Rated 5 out of 5 by HC from Produced superb immunofluorescence nuclearProduced superb immunofluorescence nuclear staining in formalin-fixed HepG2 cells. -SCBT QC
    Date published: 2015-04-13
    Rated 5 out of 5 by LF from Satisfactory Western Blot data of RelB expressionSatisfactory Western Blot data of RelB expression in non-transfected and human RelB transfected 293T whole cell lysates and KNRK nuclear extract . -SCBT QC
    Date published: 2013-11-12
    • y_2026, m_10, d_18, h_6
    • bvseo_bulk, prod_bvrr, vn_bulk_3.0.48
    • cp_1, bvpage1
    • co_hasreviews, tv_0, tr_3
    • loc_zh_CN, sid_166417, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
    • clientName_scbt
    • bvseo_sdk, java_sdk, bvseo-4.0.0
    • CLOUD, getReviews, 15ms
    • REVIEWS, PRODUCT
    RelB 抗体 (F-2) is rated 4.0 out of 5 by 3.
    • y_2026, m_10, d_18, h_6
    • bvseo_bulk, prod_bvrr, vn_bulk_3.0.48
    • cp_1, bvpage1
    • co_hasreviews, tv_0, tr_3
    • loc_zh_CN, sid_166417, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
    • clientName_scbt
    • bvseo_sdk, java_sdk, bvseo-4.0.0
    • CLOUD, getAggregateRating, 108ms
    • REVIEWS, PRODUCT
    1-800-457-3801
    访问 Santa Cruz Animal Health|访问 San Juan Ranch
    Santa Cruz Biotechnology, Inc. 是生物医学研究市场产品开发的世界领导者。请拨打1-800-457-3801联系我们。
    版权所有© 2007-2026 Santa Cruz Biotechnology, Inc. 保留所有权利。”Santa Cruz Biotechnology” 和Santa Cruz Biotechnology, Inc.的商标，”Santa Cruz Animal Health”, “San Juan Ranch”, “Supplement of Champions”, San Juan Ranch的商标，”UltraCruz”, “ChemCruz”, “ImmunoCruz”, “ExactaCruz”, 和 “EZ Touch”是Santa Cruz Biotechnology, Inc.的注册商标。所有商标均为其各自所有者的财产。