rat endothelium Antibody (OX43): sc-53109
- rat endothelium Antibody (OX43) is a mouse monoclonal IgG1 κ rat endothelium antibody, cited in 3 publications, provided at 200 µg/ml
- raised against peritoneal macrophages of rat origin
- rat endothelium Antibody (OX43) is recommended for detection of a 90 kDa antigen on all vascular endothelial cells of mouse and rat origin by IP, IF and FCM
- Anti-rat endothelium Antibody (OX43) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for rat endothelium Antibody (OX43). These reagents are now offered in bundles with rat endothelium Antibody (OX43) (see ordering information below).
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Rat endothelium Antibody (OX43) is a mouse monoclonal IgG1 kappa light chain antibody that detects rat endothelium protein of mouse and rat origin by immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). Rat endothelium (OX43) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. The endothelium, composed of simple squamous epithelial cells, lines the lumen of all blood vessels and plays a vital role in maintaining vascular homeostasis. A selective barrier regulates the passage of substances between the bloodstream and surrounding tissues, which is crucial for processes such as nutrient delivery and waste removal. Additionally, endothelium secretes various vasoactive substances that influence the contraction and relaxation of vascular smooth muscle, modulating vascular tone and blood flow. This dynamic tissue also plays a significant role in regulating coagulation and leukocyte adhesion, making endothelium essential for both normal physiological functions and response to injury or inflammation. Using rat endothelium (OX43) monoclonal antibody, researchers can gain valuable insights into endothelial biology and its implications in various cardiovascular diseases.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
rat endothelium Antibody (OX43) References:
- Regulation of the biosynthesis of acyl analogs of platelet-activating factor by purinergic agonist in endothlial cells. | Balestrieri, ML. and Lee, T. 2000. FEBS Lett. 479: 63-6. PMID: 10940389
- Increased neutrophil adherence in psoriasis: role of the human endothelial cell receptor Thy-1 (CD90). | Wetzel, A., et al. 2006. J Invest Dermatol. 126: 441-52. PMID: 16374458
- Relation of endothelial cell function to erectile dysfunction: implications for treatment. | Guay, AT. 2005. Am J Cardiol. 96: 52M-56M. PMID: 16387568
- Endothelial cell function on 2D and 3D micro-fabricated polymer scaffolds: applications in cardiovascular tissue engineering. | Bianchi, F., et al. 2006. J Biomater Sci Polym Ed. 17: 37-51. PMID: 16411597
- Lung microvascular endothelial cell injury caused by treatment with polymorphonuclear neutrophils and low-IgM serum: a model of transfusion-related acute lung injury. | Nishimura, M., et al. 2006. Lung. 184: 25-32. PMID: 16598649
- Endothelial cell expression of galectin-1 induced by prostate cancer cells inhibits T-cell transendothelial migration. | He, J. and Baum, LG. 2006. Lab Invest. 86: 578-90. PMID: 16607379
- c-Src is the primary signaling mediator of polychlorinated biphenyl-induced interleukin-8 expression in a human microvascular endothelial cell line. | Eum, SY., et al. 2006. Toxicol Sci. 92: 311-20. PMID: 16611624
- MRC OX-43: a monoclonal antibody which reacts with all vascular endothelium in the rat except that of brain capillaries. | Robinson, AP., et al. 1986. Immunology. 57: 231-7. PMID: 2936678
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
rat endothelium Antibody (OX43) | sc-53109 | 200 µg/ml | $322.00 | |||
rat endothelium Antibody (OX43): m-IgG Fc BP-HRP Bundle | sc-528549 | 200 µg Ab; 10 µg BP | $361.00 | |||
rat endothelium Antibody (OX43): m-IgGκ BP-HRP Bundle | sc-520947 | 200 µg Ab, 40 µg BP | $361.00 | |||
rat endothelium Antibody (OX43) AC | sc-53109 AC | 500 µg/ml, 25% agarose | $424.00 | |||
rat endothelium Antibody (OX43) HRP | sc-53109 HRP | 200 µg/ml | $322.00 | |||
rat endothelium Antibody (OX43) FITC | sc-53109 FITC | 200 µg/ml | $336.00 | |||
rat endothelium Antibody (OX43) PE | sc-53109 PE | 200 µg/ml | $349.00 | |||
rat endothelium Antibody (OX43) Alexa Fluor® 488 | sc-53109 AF488 | 200 µg/ml | $364.00 | |||
rat endothelium Antibody (OX43) Alexa Fluor® 546 | sc-53109 AF546 | 200 µg/ml | $364.00 | |||
rat endothelium Antibody (OX43) Alexa Fluor® 594 | sc-53109 AF594 | 200 µg/ml | $364.00 | |||
rat endothelium Antibody (OX43) Alexa Fluor® 647 | sc-53109 AF647 | 200 µg/ml | $364.00 | |||
rat endothelium Antibody (OX43) Alexa Fluor® 680 | sc-53109 AF680 | 200 µg/ml | $364.00 | |||
rat endothelium Antibody (OX43) Alexa Fluor® 790 | sc-53109 AF790 | 200 µg/ml | $364.00 |