Date published: 2025-9-11

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Rad21 抗体 (H-12): sc-166973

5.0(4)
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说明书
  • Rad21抗体(H-12)是小鼠单克隆IgG2b κ, 在3篇文献中引用,规格为200 µg/ml
  • 针对氨基酸143-352的图谱,在Rad21的内部区域,human起源
  • 推荐用于 mouse, rat 和 human 来源的Rad21 WB, IP, IF 和 ELISA检测
  • m-IgG Fc BP-HRPm-IgGκ BP-HRP是Rad21 Antibody (H-12) 适用于 WB 应用。 的首选辅助检测试剂,这些试剂现与Rad21 Antibody (H-12) 打包提供(请参阅下面的订购信息)。

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関連項目

Rad21是主要的黏着蛋白亚基之一,它能够将姐妹染色单体结合在一起,直至后期阶段,此时由分离酶(一种类似半胱氨酸天冬氨酸蛋白酶的酶)进行蛋白水解切割,从而实现染色体分离。RAD21与REC8相互作用,形成黏着蛋白复合物,该复合物在姐妹染色单体排列中发挥作用。RAD21还参与DNA双链断裂的修复,对细胞有丝分裂生长至关重要。Rad 21在凋亡之前会受到各种刺激诱导的C端切割。切割产物迁移到细胞质中,参与凋亡途径的早期事件,并以正反馈的方式放大细胞死亡信号。RAD21基因与癌细胞的侵袭和转移有关,RAD21是癌症治疗的潜在靶点,可能通过诱导DNA损伤来增强化疗药物的抗肿瘤活性。

仅限研究使用。不适用于诊断和治疗用途。

订购信息

产品名称产品编号规格价格数量收藏夹

Rad21 抗体 (H-12)

sc-166973
200 µg/ml
$316.00

Rad21 (H-12): m-IgG Fc BP-HRP 套装

sc-537554
200 µg Ab; 10 µg BP
$354.00

Rad21 (H-12): m-IgGκ BP-HRP 套装

sc-534852
200 µg Ab; 40 µg BP
$354.00

What is the recommended fixation method for immunofluorescence staining with Rad21 (H-12): sc-166973 monoclonal antibody?

Asked by: DefinitelyNotMatt
Thank you for your inquiry. We recommend fixing cells for 5 minutes in -10°C methanol and allowing to air dry. The full protocol can be viewed here: https://www.scbt.com/scbt/resources/protocols/immunofluorescence-cell-staining
Answered by: Technical Support
Date published: 2017-02-24
  • y_2025, m_8, d_30, h_9CST
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Rated 5 out of 5 by from works good for WBtother with sc-271601 antibody this also works pretty nice.
Date published: 2017-11-30
Rated 5 out of 5 by from Works with PFA FixationGreat for use in IF with PFA fixed samples, shows a bright signal localized to the nucleus.
Date published: 2017-02-02
Rated 5 out of 5 by from Light band in WB in T24 and CaklLight band in WB in T24 and Cakl-1 whole cell lysates. -SCBT QC
Date published: 2015-03-19
Rated 5 out of 5 by from Strong band in WB in HeLa and MOLTStrong band in WB in HeLa and MOLT-4 nuclear extracts. -SCBT QC
Date published: 2014-04-02
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Rad21 抗体 (H-12) is rated 5.0 out of 5 by 4.
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