Prostaglandin F2alpha CAS: 551-11-1
MF: C20H34O5
MW: 354.5
A potent smooth muscle contricting prostaglandin shown to inhibit adipocyte differentiation.

Prostaglandin F (CAS 551-11-1)

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备用名: Prostaglandin F2α; PGF2α; Dinoprost
应用; Prostaglandin F2α is a potent smooth muscle contricting prostaglandin shown to inhibit adipocyte differentiation
CAS号码: 551-11-1
分子量: 354.5
分子式: C20H34O5
仅供科研使用。不可用于诊断或治疗。
* 参考分析证明 大量特定数据 (包括水 含量).

Prostaglandin F is a major uterine prostaglandin that has been shown to cause contraction of vascular, bronchial, intestinal, myometrial smooth muscle, and to inhibit adipocyte differentiation. Research has demonstrated that PGF inhibits nitric oxide production by the uterine tissue, increases uterine contractility, and displays potent luteolytic activity. Prostaglandin F is an activator of PGFR.


参考文献

1. Speroff, L., et al. 1970. Am. J. Obstet. Gynecol. 107: 1111-1130. PMID: 4914185
2. Samuelsson, B., et al. 1978. Annu. Rev. Biochem. 47: 997-1029. PMID: 209733
3. Vincent, D.L. and Inskeep, E.K. 1986. Prostaglandins. 31: 715-733. PMID: 3460114
4. Abramovitz, M., et al. 1994. J. Biol. Chem. 269: 2632-2636. PMID: 8300593
5. Crankshaw, D.J. and Gaspar, V. 1995. J. Reprod. Fertil. 103: 55-61. PMID: 7535849
6. Miller, C.W., et al. 1996. Endocrinology. 137: 5641-5650. PMID: 8940395
7. Dong, Y.L., et al. 1997. Am. J. Obstet. Gynecol. 177: 907-917. PMID: 9369844

物理状态 :
Solid
溶解度 :
Soluble in ethanol (~100 mg/ml), acetone, methanol, ethyl acetate, chloroform, DMSO (~100 mg/ml), DMF (~100 mg/ml), and PBS (pH 7.2) (~10 mg/ml). Insoluble in water.
保存 :
Store at -20° C
熔点 :
25-35° C
沸点 :
~531° C at 760 mmHg (Predicted)
密度 :
~1.2 g/cm3 (Predicted)
折射率 :
n20D 1.57
光学活性 :
α20/D 24°, c = 2 in ethanol
仅供科研使用。不可用于诊断或治疗。
RTECS :
UK8020000
PubChem CID :
5280363
默克索引 :
14: 7878
MDL 号码 :
MFCD00135231
SMILES :

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