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Prostaglandin E2 p-acetamidophenyl ester (CAS 57790-52-0)

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Alternate Names:
PGE2 p-acetamidophenyl ester
Application:
Prostaglandin E2 p-acetamidophenyl ester is a crystalline derivative of PGE2 esterified at the carboxylic acid moiety
CAS Number:
57790-52-0
Purity:
>98%
Molecular Weight:
485.6
Molecular Formula:
C28H39NO6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Prostaglandin E2 p-acetamidophenyl ester is a crystalline derivative of PGE2 (sc-201225) that is esterified at the carboxylic acid moiety. PGE2 is one of the primary COX products of arachidonic acid (sc-200770), that asserts a plethora of biological activity through binding to the type E prostaglandin receptors; EP1,2,3, and 4. Selective antagonists of a particular EP receptor sub-type have been exceptionally difficult to produce, therefore structure-activity studies are important to determine the binding characteristics of PGE2 to these EP receptors in order to develop novel selective EP antagonists. Prostaglandin E2 p-acetamidophenyl ester could potentially be used in structure-activity studies to determine ways to selectively antagonize specific EP receptor sub-types.


Prostaglandin E2 p-acetamidophenyl ester (CAS 57790-52-0) References

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  2. Repeated injection of prostaglandin E2 in rat paws induces chronic swelling and a marked decrease in pain threshold.  |  Willis, AL. and Cornelsen, M. 1973. Prostaglandins. 3: 353-7. PMID: 4729578
  3. Prostaglandin E2 down-regulates the expression of HLA-DR antigen in human colon adenocarcinoma cell lines.  |  Arvind, P., et al. 1995. Biochemistry. 34: 5604-9. PMID: 7727422
  4. International Union of Pharmacology classification of prostanoid receptors: properties, distribution, and structure of the receptors and their subtypes.  |  Coleman, RA., et al. 1994. Pharmacol Rev. 46: 205-29. PMID: 7938166
  5. Cervical ripening before induction of labor: a randomized trial of prostaglandin E2 gel versus low-dose oxytocin.  |  Jackson, GM., et al. 1994. Am J Obstet Gynecol. 171: 1092-6. PMID: 7943077
  6. Metabolomics Analysis of Serum and Urine After Bean Consumption by Patients with Peripheral Arterial Disease[J].  |  Wang L, Zahradka P, Taylor C. 2016. The FASEB Journal,., 30:: 682.10-682.10.
  7. Fecal metabolomics reveals the positive effect of ethanol extract of propolis on T2DM mice[J].  |  Wang C, Zhao H, Xu K,., 2023,. Food Science and Human Wellness. 12(1):: 161-172.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Prostaglandin E2 p-acetamidophenyl ester, 1 mg

sc-205451
1 mg
$84.00

Prostaglandin E2 p-acetamidophenyl ester, 5 mg

sc-205451A
5 mg
$379.00