Date published: 2026-5-9

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Propionamidine hydrochloride (CAS 39800-84-5)

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CAS Number:
39800-84-5
Molecular Weight:
108.57
Molecular Formula:
C3H9ClN2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Propionamidine hydrochloride represents an amide derivative stemming from propanamide, a pivotal compound in the creation of diverse compounds and pharmaceuticals. Notably, it is posited to function as an inhibitor for specific enzymes, including the significant acetylcholinesterase. This inhibition is thought to originate from its binding to the enzyme′s active site, effectively impeding its catalytic capacity. Beyond enzyme interactions, there′s a belief that this compound engages with various proteins linked to signal transduction pathways, thereby exerting a modulatory influence on their operational dynamics.


Propionamidine hydrochloride (CAS 39800-84-5) References

  1. Bleomycin: Synthetic and Mechanistic Studies.  |  Boger, DL. and Cai, H. 1999. Angew Chem Int Ed Engl. 38: 448-476. PMID: 29711767
  2. A partially fluorinated ligand for two super-hydrophobic porous coordination polymers with classic structures and increased porosities.  |  Wang, C., et al. 2021. Natl Sci Rev. 8: nwaa094. PMID: 34691585
  3. Synthesis of amidine derivatives of alkylthiosulfuric acids as potential antiradiation agents  |  Sosnovsky, G., & Schneider, P. 1963. Tetrahedron. 19(9): 1313-1318.
  4. Ring transformations in reactions of heterocyclic halogeno compounds with nucleophiles (V): Conversion of some 2‐alkyl‐, 2‐aryl‐and 2, 5‐dialkyl‐4‐chloropyrimidines by potassium amide in liquid ammonia into 4‐alkyl derivatives of 2‐alkyl‐or 2‐aryl‐s‐triazines  |  Van der Plas, H. C., Haase, B., Zuurdeeg, B., & Vollering, M. C. 1966. Recueil des Travaux Chimiques des Pays‐Bas. 85(11): 1101-1113.
  5. Inverse Electron Demand Diels-Alder Reactions of Heterocyclic Azadienes:[4+ 2] Cycloaddition Reaction of Amidines with 1, 3, 5-Triazines.  |  Boger, D. L., & Kochanny, M. J. 1994. The Journal of Organic Chemistry. 59(17): 4950-4955.
  6. Total synthesis of bleomycin A2 and related agents. 2. Synthesis of (-)-Pyrimidoblamic acid, epi-(+)-Pyrimidoblamic acid,(+)-Desacetamidopyrimidoblamic acid, and (-)-Descarboxamidopyrimidoblamic acid  |  Boger, D. L., Honda, T., & Dang, Q. 1994. Journal of the American Chemical Society. 116(13): 5619-5630.
  7. CF3-MOF enhanced pervaporation selectivity of PDMS membranes for butanol separation  |  Ren, C., Si, Z., Qu, Y., Li, S., Wu, H., Meng, F.,.. & Qin, P. 2022. Separation and Purification Technology. 284: 120255.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Propionamidine hydrochloride, 5 g

sc-286698
5 g
$150.00