Date published: 2025-9-9

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Progesterone Receptor 抗体 (F-2): sc-166170

4.7(3)
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说明书
  • Progesterone Receptor抗体(F-2)是小鼠单克隆IgG2b κ, 在2篇文献中引用,规格为200 µg/ml
  • 免疫human物种的PR的氨基酸375-564
  • 推荐用于 mouse, rat 和 human 来源的PR-A and PR-B WB, IP, IF, IHC(P) 和 ELISA检测
  • 可用于ChIP的TransCruz试剂(sc-166170 X, 200 µg/0.1 ml)
  • 看 Progesterone Receptor (F-4): sc-166169,可查看有标记的 Progesterone Receptor 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgG2b BP-HRP 是Progesterone Receptor 抗体 (F-2) 在 WB and IHC(P) 应用中的首选二抗检测试剂。该试剂现与Progesterone Receptor 抗体 (F-2) 组合成套装提供。 (请参阅下面的订购信息)。

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関連項目

孕酮的作用是由孕酮受体的两种功能不同的亚型PR-A和PR-B介导的,这两种亚型是由PR基因单个拷贝内的不同、雌激素可诱导的启动子转录而来的。PR-B的前164个氨基酸在PR-A中缺失。与孕酮结合的PR-A和PR-B具有不同的转录激活特性。具体来说,PR-B在大多数细胞和启动子环境中作为转录激活剂发挥作用,而PR-A在转录上是不活跃的,并作为类固醇激素受体转录活性的强配体依赖性反显性抑制因子发挥作用。两种PR亚型中都存在一个抑制域(ID),该抑制域映射到受体的氨基末端。有趣的是,ID仅在PR-A中具有功能活性,并且是PR-A通过类固醇激素进行反式抑制所必需的,这表明PR-A和PR-B在细胞中可能具有不同的构象。

仅限研究使用。不适用于诊断和治疗用途。

订购信息

产品名称产品编号规格价格数量收藏夹

Progesterone Receptor 抗体 (F-2)

sc-166170
200 µg/ml
$316.00

Progesterone Receptor (F-2): m-IgG2b BP-HRP 套装

sc-548512
200 µg Ab; 10 µg BP
$354.00

Progesterone Receptor 抗体 (F-2) X

sc-166170 X
200 µg/0.1 ml
$316.00

We're working with the PR antibody (sc-166170) in rat brain at a 1:100 primary concentration. We are getting two clear bands on westerns, however they are at ~60kDa and ~80kDa and not the expected ~90 kDa and ~120 kDa. Do you know what might cause this?

Asked by: neurotrauma_lab
Thank you for your question. Please contact technical service by emailing scbt@scbt.com or call (800)-457-3801.
Answered by: BlakeJ
Date published: 2023-08-09

When should the TransCruz reagent sc-166170 X be used instead of the standard form sc-166170?

Asked by: AbPolly
Thank you for your question. We recommend using the TransCruz reagent form when performing ChIP or GelShift assays. This form can also be used in other applications such as Western Blot or IHC, but the dilution should be adjusted by a factor of 10 to account for the higher original concentration.
Answered by: Technical Support
Date published: 2017-02-24
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Rated 5 out of 5 by from Exceptional immunoperoxidase nuclear stainingExceptional immunoperoxidase nuclear staining in formalin fixed, paraffin-embedded human breast tissue. -SCBT QC
Date published: 2015-04-06
Rated 4 out of 5 by from Positive result in western blot analysisPositive result in western blot analysis of PR expression in T-47D whole cell lysate. -SCBT QC
Date published: 2015-03-22
Rated 5 out of 5 by from Published WB and IHC results using murinePublished WB and IHC results using murine mammary tumor tissue sections. -SCBT Publication Review
Date published: 2015-01-23
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Progesterone Receptor 抗体 (F-2) is rated 4.7 out of 5 by 3.
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