Polistes Mastoparan CAS: 74129-19-4
MF: C77H127N21O18
MW: 1634.96
A binder and inhibitor of calmodulin.

Polistes Mastoparan (CAS 74129-19-4)

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应用; A binder and inhibitor of calmodulin
CAS号码: 74129-19-4
分子量: 1634.96
分子式: C77H127N21O18
* 参考分析证明 大量特定数据 (包括水 含量).
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Polistes Mastoparan is a peptide found in wasp venom. It binds to and inhibits CAM (calmodulin), a calcium binding protein found in eukaryotic cells. It is suggested that a net positive charge on the peptide is important for anti-calmodulin activity because acetylation of the peptides is reported to reduce their inhibitory effect. It is also suggested that Polistes Mastoparan acts partly by stimulation of phospholipase activity.


参考文献

1. Nakajima, T., et al. 1985. Peptides. 6: 425-430. PMID: 3831970
2. Barnette, M.S., et al. 1983. Biochem. Pharmacol. 32: 2929-2933. PMID: 6313011
3. Argiolas, A., et al. 1983. J. Biol. Chem. 258: 13697-13702. PMID: 6643447

物理状态 :
Solid
溶解度 :
Soluble in Ethanol
保存 :
Store at -20° C
仅供科研使用。不可用于诊断或治疗。
德国水公害等级 :
3
PubChem CID :
16132143
SMILES :
CC[[email protected]](C)[[email protected]@H](C(=O)NCC(=O)N[[email protected]@H](CCC(=O)N)C(=O)N[[email protected]@H](CC1=CN=CN1)C(=O)N[[email protected]@H]([[email protected]@H](C)CC)C(=O)N[[email protected]@H](CC(C)C)C(=O)N[[email protected]@H](CO)C(=O)N[[email protected]@H](C(C)C)C(=O)N[[email protected]@H](CC(C)C)C(=O)N)NC(=O)[[email protected]](CCCCN)NC(=O)[[email protected]](CCCCN)NC(=O)[[email protected]](CC2=CNC3=CC=CC=C32)NC(=O)[[email protected]](CC(=O)O)NC(=O)[[email protected]](C(C)C)N

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