(±)15-HEPE (CAS 88852-33-9)

±)15-HEPE, identified by the CAS number 88852-33-9, is a hydroxy-eicosapentaenoic acid derivative of eicosapentaenoic acid (EPA), which is an essential omega-3 fatty acid predominantly sourced from marine life. This chemical consists of a hydroxyl group at the fifteenth carbon, and the (±) prefix indicates it includes both enantiomers of the molecule. In research contexts, (±)15-HEPE is studied for its involvement in cellular signaling pathways that regulate inflammatory responses. As a bioactive lipid mediator, it is particularly notable for its role in modulating the synthesis and activity of various inflammatory mediators, including cytokines and eicosanoids. This modulation occurs through its interaction with specific receptor sites on cell membranes, influencing signaling pathways that can alter the expression of genes associated with inflammation. Researchers utilize (±)15-HEPE to explore its potential in elucidating the molecular mechanisms by which omega-3 fatty acids can influence anti-inflammatory signaling. By studying this compound, scientists gain insights into the complex biochemistry of inflammation resolution, offering a deeper understanding of how lipid mediators can impact cellular processes and contribute to maintaining cellular and tissue homeostasis. This research is crucial for advancing our knowledge of the natural regulatory mechanisms that control inflammation and cellular behavior.