Date published: 2026-10-26

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Plk 抗体 (AZ24): sc-53418

4.3(3)
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说明书
  • Plk抗体(AZ24)是小鼠单克隆IgG2a κ, 在2篇文献中引用,规格为200 µg/ml
  • 针对Xenopus来源的杆状病毒表达的polo激酶
  • 推荐用于 mouse, rat, human 和 Xenopus 来源的Plk WB 和 IP检测
  • 看 Plk (F-8): sc-17783,可查看有标记的 Plk 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgG Fc BP-HRP、 2a BP-HRP">m-IgG2a BP-HRP和m-IgGκ BP-HRP是Plk Antibody (AZ24) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与Plk Antibody (AZ24) 打包提供(请参阅下面的订购信息)。
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関連項目

Plk(代表Polo样激酶)编码一种丝氨酸/苏氨酸激酶,该激酶与Polo和CDC5密切相关,Polo和CDC5分别是果蝇和酿酒酵母通过有丝分裂所必需的基因。Polo和CDC5都编码参与调节有丝分裂纺锤体功能的蛋白质。Plk蛋白在细胞周期的S期和G2期在细胞中积累,并且在有丝分裂开始时,蛋白质含量和催化活性均达到峰值,随后在有丝分裂后迅速降低。在有丝分裂活跃的组织(如结肠和胎盘)以及各种起源的肿瘤中,均可检测到Plk的表达。还有人认为,Plk可以作为细胞增殖的标志物。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Plk 抗体 (AZ24) 参考文献:

  1. Polo样激酶(Plk)1作为前列腺癌治疗靶点。  |  Reagan-Shaw, S. and Ahmad, N. 2005. IUBMB Life. 57: 677-82. PMID: 16223707
  2. 通过外泌体递送的siRNA在膀胱癌中沉默PLK-1。  |  Greco, KA., et al. 2016. Urology. 91: 241.e1-7. PMID: 26876462
  3. 木犀草素制备的氧化锌纳米结构显示出 PLK-1 介导的抗乳腺癌活性。  |  Kollur, SP., et al. 2021. Biomolecules. 11: PMID: 33807771
  4. 通过高含量表型筛选发现的PLK抑制剂能促进人PSC衍生心肌细胞的成熟  |  Feng, M., et al. 2022. Biochem Biophys Res Commun. 620: 113-120. PMID: 35780579
  5. PLK-1与检查点螺旋酶PICH相互作用,介导细胞氧化应激反应。  |  Dutta, A., et al. 2022. Epigenomes. 6: PMID: 36278682
  6. BUB-1结合的PLK-1引导CDC-20动点聚集,确保胚胎有丝分裂的及时进行。  |  Houston, J., et al. 2023. Curr Biol. 33: 2291-2299.e10. PMID: 37137308
  7. 线粒体蛋白SPD-3的缺失会提高PLK-1的水平并使有丝分裂过程失调。  |  Chen, YZ., et al. 2023. Life Sci Alliance. 6: PMID: 37684042
  8. PLK-3介导的BAP1磷酸化可预防糖尿病性视网膜病变。  |  Qin, T., et al. 2024. Biochem Pharmacol. 226: 116374. PMID: 38906226
  9. Polo样激酶(PLK)抑制剂研究进展:专利审查(2018年至今)。  |  Bian, S., et al. 2024. Expert Opin Ther Pat. 34: 789-806. PMID: 38994687
  10. Plk是酿酒酵母Cdc5的功能同源物,Plk活性升高可诱导多种分隔结构。  |  Lee, KS. and Erikson, RL. 1997. Mol Cell Biol. 17: 3408-17. PMID: 9154840

订购信息

产品名称产品编号规格价格数量收藏夹

Plk 抗体 (AZ24)

sc-53418
200 µg/ml
$322.00

Plk (AZ24): m-IgG Fc BP-HRP 套装

sc-536962
200 µg Ab; 10 µg BP
$361.00

Plk (AZ24): m-IgGκ BP-HRP 套装

sc-534139
200 µg Ab; 40 µg BP
$361.00

Plk (AZ24): m-IgG2a BP-HRP 套装

sc-547910
200 µg Ab; 10 µg BP
$361.00

I am using the LiCor/Odyssey system. Which secondary antibody do you recommend using with Plk (AZ24): sc-53418?

Asked by: jerojero
We recommend using one of our our exclusive Mouse IgG Binding Proteins conjugated to CFL 680 or CFL 790. They are suitable for use with Near-Infrared (NIR) detection systems, such as LI-COR/Odyssey and other comparable systems. A complete list of available binding proteins is available on our website here: https://www.scbt.com/scbt/browse/support-products-mouse-igg-binding-proteins/_/N-ecrety
Answered by: Technical Support
Date published: 2017-02-27
  • y_2026, m_10, d_25, h_6CST
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Rated 4 out of 5 by Brave from Antibody featureThe antiboy is good and can see strong band in WB using A2780 cell
Date published: 2016-12-16
Rated 5 out of 5 by LM from Worked well with transfected lysate by WBWorked well with transfected lysate by WB -SCBT QC
Date published: 2015-02-17
Rated 4 out of 5 by LM from Strong band seen in WB using HeLa whole cellStrong band seen in WB using HeLa whole cell lysate. -SCBT QC
Date published: 2013-01-27
  • y_2026, m_10, d_25, h_6
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Plk 抗体 (AZ24) is rated 4.3 out of 5 by 3.
  • y_2026, m_10, d_25, h_6
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.48
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_3
  • loc_zh_CN, sid_53418, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 6ms
  • REVIEWS, PRODUCT