Date published: 2026-10-16

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PDI 抗体 (A-1): sc-376370

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说明书
  • PDI抗体(A-1)是小鼠单克隆IgG1 κ, 在4篇文献中引用,规格为200 µg/ml
  • 特异性抗原位于human物种的PDI的内部区域内的氨基酸221-257之间
  • 推荐用于 mouse, rat 和 human 来源的precursor and mature PDI WB, IP, IF, IHC(P) 和 ELISA检测
  • 看 PDI (C-2): sc-74551,可查看有标记的 PDI 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgG Fc BP-HRP和 m-IgG1 BP-HRP是PDI Antibody (A-1) for WB and IHC(P) applications. 的首选辅助检测试剂,这些试剂现与PDI Antibody (A-1) 打包提供(请参阅下面的订购信息)。
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氧化还原酶-蛋白质二硫键异构酶(PDI)是一种同源二聚体,由催化硫醇-二硫键交换的亚基组成,介导新生蛋白质的折叠并作为分子伴侣发挥作用。PDI定位于内质网(ER)腔内,与折叠辅助蛋白(如免疫球蛋白重链结合蛋白BiP)一起参与三级和四级蛋白质的加工过程。细胞表面的PDI通过诱导整合素介导的粘附受体-配体相互作用中的硫氢基介导的构象变化,从而调节整合素的反应和细胞粘附。此外,PDI还作为另外两个更复杂的酶系统的亚基发挥作用:脯氨酰-4-羟化酶和三酰甘油转移蛋白。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

PDI 抗体 (A-1) 参考文献:

  1. PDI家族蛋白ERp29识别分子伴侣钙网蛋白的P域。  |  Nakao, H., et al. 2017. Biochem Biophys Res Commun. 487: 763-767. PMID: 28456374
  2. 新型二甲基亚甲基桥联三苯胺-PDI受体,用于体异质结有机太阳能电池。  |  Xiong, Y., et al. 2017. Adv Sci (Weinh). 4: 1700110. PMID: 29051855
  3. PDI介导的DRP1的S-亚硝基化促进CA1神经元中的DRP1-S616磷酸化及线粒体裂解。  |  Lee, DS. and Kim, JE. 2018. Cell Death Dis. 9: 869. PMID: 30158524
  4. 光动力灭活(PDI)对抗食品工业生物膜的新趋势--综述。  |  Wang, D., et al. 2021. Foods. 10: PMID: 34828868
  5. TPPS/PDI的电子给体-受体界面促进了电荷转移,从而提高了光催化氢的效率。  |  Yang, J., et al. 2022. Adv Sci (Weinh). 9: e2201134. PMID: 35404517
  6. CDDO-Me通过调节NF-κB-PDI介导的DRP1的S-亚硝基化,在类星体变性中废除了异常线粒体伸长。  |  Lee, DS., et al. 2023. Int J Mol Sci. 24: PMID: 36982949
  7. 反式二硫代PDI中振动和自旋-轨道耦合在荧光猝灭中的相互作用。  |  Dakua, KK., et al. 2023. J Chem Phys. 159: PMID: 37712797
  8. PDI-三苯甲基二聚体和三聚体的合成和暗态EPR特性。  |  Kopp, K., et al. 2024. Chemistry. 30: e202303635. PMID: 38055217
  9. 提高了含CxxC基序的PDI家族成员的酶活性。  |  Kuramochi, T., et al. 2024. Chem Commun (Camb). 60: 6134-6137. PMID: 38829522
  10. TMX5/TXNDC15是PDI家族的天然诱捕突变体,是蛋白质稳定因子ERp44的受体。  |  Soldà, T., et al. 2024. Life Sci Alliance. 7: PMID: 39348940

订购信息

产品名称产品编号规格价格数量收藏夹

PDI 抗体 (A-1)

sc-376370
200 µg/ml
$322.00

PDI (A-1): m-IgG Fc BP-HRP 套装

sc-540555
200 µg Ab; 10 µg BP
$361.00

PDI (A-1): m-IgG1 BP-HRP 套装

sc-542203
200 µg Ab; 20 µg BP
$361.00

PDI (A-1) 中和勝肽

sc-376370 P
100 µg/0.5 ml
$69.00

What application is the blocking peptide sc-376370 P appropriate for?

Asked by: Cweed
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-24
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Rated 5 out of 5 by TinTin from Awesome antibodyDependable and strong are two words I would use for this antibody! It's a great solid choice if you're looking to detect PDI in IHC or Western blot.
Date published: 2017-01-19
Rated 5 out of 5 by NZ from Produced a clear band with MOLTProduced a clear band with MOLT-4, Raji and A2058 whole cell lysates. -SCBT QC
Date published: 2015-06-09
Rated 5 out of 5 by LR from Band detected at expected mw in ABand detected at expected mw in A-431 whole cell lysate. -SCBT QC
Date published: 2015-03-30
Rated 3 out of 5 by MS from Worked ok with transfected lysate by WBWorked ok with transfected lysate by WB. -SCBT QC
Date published: 2015-03-07
Rated 5 out of 5 by JL from Superb immunoperoxidase cytoplasmic stainingSuperb immunoperoxidase cytoplasmic staining in formalin fixed, paraffin-embedded human small intestine tissue. -SCBT QC
Date published: 2013-08-02
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PDI 抗体 (A-1) is rated 4.6 out of 5 by 5.
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