Date published: 2025-9-9

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PCB 抗体 (F-3): sc-365491

5.0(1)
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说明书
  • PCB抗体(F-3)是小鼠单克隆IgG3 (kappa轻链),规格为200 µg/ml
  • 特异性抗原位于human物种的PCB的C-terminus附近的氨基酸1015-1041之间
  • 推荐用于 mouse, rat 和 human 来源的PCB WB, IP, IF 和 ELISA检测; 也和以下物种反应,包括: 和 equine, canine and bovine
  • m-IgG3 BP-HRP是PCB Antibody (F-3) 适用于 WB 应用。 的首选辅助检测试剂,该试剂现与PCB Antibody (F-3) 搭配使用(请参阅下面的订购信息)。

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    関連項目

    丙酮酸羧化酶(PCB)是一种生物素化的线粒体酶,它催化丙酮酸以组织特异性方式合成草酰乙酸。除了与生物素辅因子共价结合外,PCB还含有ATP和底物丙酮酸附着的共有序列。PCB基因位于11号染色体的长臂上。已知PCB代谢的突变(丙酮酸羧化酶缺乏症)会导致乳酸性酸中毒、低血糖和精神发育迟滞。

    仅限研究使用。不适用于诊断和治疗用途。

    Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

    LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

    PCB 抗体 (F-3) 参考文献:

    1. P-糖蛋白在恶性星形细胞瘤的临床耐药性中起作用吗?  |  Ashmore, SM., et al. 1999. Anticancer Drugs. 10: 861-72. PMID: 10630353
    2. 遗传性肥胖中的丙酮酸羧化酶  |  Lynch, CJ., et al. 1992. Am J Physiol. 262: E608-18. PMID: 1375435
    3. 丙酮酸羧化酶抑制剂。  |  Zeczycki, TN., et al. 2010. Open Enzym Inhib J. 3: 8-26. PMID: 22180764
    4. 造血环氧化酶-1缺陷对小鼠肥胖相关脂肪组织炎症和代谢紊乱的影响  |  Saraswathi, V., et al. 2013. Metabolism. 62: 1673-85. PMID: 23987235
    5. Erianin 以丙酮酸羧化酶依赖的方式抑制癌细胞的增殖和迁移。  |  Hong, J., et al. 2022. Fitoterapia. 157: 105136. PMID: 35093481
    6. 缺氧介导的丙酮酸羧化酶抑制作用可导致免疫抑制。  |  Coleman, MF., et al. 2024. Breast Cancer Res. 26: 96. PMID: 38849928
    7. 肝脏和肝脏肿瘤中丙酮酸羧化酶的酶学和免疫学研究  |  Chang, LO. and Morris, HP. 1973. Cancer Res. 33: 2034-41. PMID: 4353477
    8. 以阿维丁-配体共轭物为酶调节剂的均相酶免疫测定。  |  Bacquet, C. and Twumasi, DY. 1984. Anal Biochem. 136: 487-90. PMID: 6372543
    9. MDR1基因特异性单克隆抗体C494与丙酮酸羧化酶发生交叉反应  |  Rao, VV., et al. 1994. Cancer Res. 54: 1536-41. PMID: 7511043
    10. 丙酮酸羧化酶和丙酮酸脱氢酶复合物失调。  |  Robinson, BH., et al. 1996. J Inherit Metab Dis. 19: 452-62. PMID: 8884569

    订购信息

    产品名称产品编号规格价格数量收藏夹

    PCB 抗体 (F-3)

    sc-365491
    200 µg/ml
    $316.00

    PCB (F-3): m-IgG3 BP-HRP 套装

    sc-550430
    200 µg Ab; 40 µg BP
    $354.00

    PCB (F-3) 中和勝肽

    sc-365491 P
    100 µg/0.5 ml
    $68.00

    What application is the blocking peptide sc-365491 P appropriate for?

    Asked by: Trav11
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Answered by: Technical Support
    Date published: 2017-03-01
    • y_2025, m_9, d_9, h_6CST
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    Rated 5 out of 5 by from Satisfactory Western blot data of PCB expressionSatisfactory Western blot data of PCB expression in non-transfected and mouse PCB transfected 293T whole cell lysates. -SCBT QC
    Date published: 2014-03-08
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    PCB 抗体 (F-3) is rated 5.0 out of 5 by 1.
    • y_2025, m_9, d_9, h_6
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    • cp_1, bvpage1
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    • REVIEWS, PRODUCT