Date published: 2025-9-9

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Pax 抗体 (D-7): sc-514352

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说明书
  • Pax 抗体 D-7 是小鼠单克隆 IgG2a κ,Pax抗体, 在1篇文献中引用,规格为200 µg/ml
  • 免疫human物种的Pax-2的氨基酸72-150
  • Pax 抗体 (D-7) 推荐用于 WB, IP, IF, IHC(P) 和 ELISA,检测mouse, rat 和human 来源的 Pax-1, Pax-2, Pax-3, Pax-5, Pax-6, Pax-7, Pax-8 and Pax-9
  • 抗Pax抗体(D-7)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 可用于凝胶迁移和ChIP的TransCruz试剂(sc-514352 X, 200 µg/0.1 ml)
  • 关于如何获取Pax (D-7): sc-514352免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP, m-IgG2a BP-HRPm-IgGκ BP-HRP 是 Pax 抗体 (D-7) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与Pax 抗体 (D-7) 组合成套装提供。 (请参阅下面的订购信息)。

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関連項目

Pax Antibody (D-7)是一种IgG2a κ小鼠单克隆Pax抗体(也称为Pan Pax抗体),可通过WB、IP、IF、IHC(P)和ELISA检测小鼠、大鼠和人类来源的Pax蛋白。Pax Antibody (D-7)既可以是非偶联的抗Pax抗体形式,也可以是多种偶联形式的抗Pax抗体,包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。核转录因子的Pax基因家族由9个家族成员组成,在胚胎发生过程中起作用,以调节细胞的时间和位置依赖性分化。此外,该家族参与成年生物体的各种信号转导途径。Pax蛋白家族的突变与人类的疾病和癌症有关。Pax基因包含成对的结构域,与果蝇中参与早期发育编程的基因具有很强的同源性。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Pax 抗体 (D-7) 参考文献:

  1. PAX2 基因在人类胚胎中的表达及在 CHARGE 综合征中的排除。  |  Tellier, AL., et al. 2000. Am J Med Genet. 93: 85-8. PMID: 10869107
  2. 成肌卫星细胞的规格化需要 Pax7。  |  Seale, P., et al. 2000. Cell. 102: 777-86. PMID: 11030621
  3. Pax-5 编码转录因子 BSAP,在 B 淋巴细胞, 发育中的中枢神经系统和成人睾丸中表达。  |  Adams, B., et al. 1992. Genes Dev. 6: 1589-607. PMID: 1516825
  4. Pax-3,一种在早期神经发生过程中表达的新型小鼠 DNA 结合蛋白。  |  Goulding, MD., et al. 1991. EMBO J. 10: 1135-47. PMID: 2022185
  5. Pax 1 是配对盒同源鼠类基因家族的成员,在发育过程中表达于分节结构中。  |  Deutsch, U., et al. 1988. Cell. 53: 617-25. PMID: 2453291
  6. 转录和表观遗传重塑中的Pax因子。  |  Mayran, A., et al. 2015. Semin Cell Dev Biol. 44: 135-44. PMID: 26234816
  7. 神经嵴发育中的PAX转录因子。  |  Monsoro-Burq, AH. 2015. Semin Cell Dev Biol. 44: 87-96. PMID: 26410165
  8. PAX蛋白及其在胰腺中的作用。  |  Panneerselvam, A., et al. 2019. Diabetes Res Clin Pract. 155: 107792. PMID: 31325538
  9. PAX基因在肾细胞癌中的作用。  |  Li, L., et al. 2024. Int J Mol Sci. 25: PMID: 38928435
  10. 甲状腺, 肾脏和 Wilms 肿瘤中通过替代剪接产生的三种人类配对盒蛋白 PAX8 异构体的不同功能特性。  |  Poleev, A., et al. 1995. Eur J Biochem. 228: 899-911. PMID: 7737192
  11. 七个 PAX 基因的染色体定位和一个新家族成员 PAX-9 的克隆。  |  Stapleton, P., et al. 1993. Nat Genet. 3: 292-8. PMID: 7981748
  12. PAX6 基因位点的突变可导致包括彼得斯氏畸形在内的多种前节畸形。  |  Hanson, IM., et al. 1994. Nat Genet. 6: 168-73. PMID: 8162071

订购信息

产品名称产品编号规格价格数量收藏夹

Pax 抗体 (D-7)

sc-514352
200 µg/ml
$316.00

Pax (D-7): m-IgG Fc BP-HRP 套装

sc-531096
200 µg Ab; 10 µg BP
$354.00

Pax (D-7): m-IgGκ BP-HRP 套装

sc-524693
200 µg Ab, 40 µg BP
$354.00

Pax (D-7): m-IgG2a BP-HRP 套装

sc-547685
200 µg Ab; 10 µg BP
$354.00

Pax 抗体 (D-7) X

sc-514352 X
200 µg/0.1 ml
$316.00

Pax 抗体 (D-7) AC

sc-514352 AC
500 µg/ml, 25% agarose
$416.00

Pax 抗体 (D-7) HRP

sc-514352 HRP
200 µg/ml
$316.00

Pax 抗体 (D-7) FITC

sc-514352 FITC
200 µg/ml
$330.00

Pax 抗体 (D-7) PE

sc-514352 PE
200 µg/ml
$343.00

Pax 抗体 (D-7) Alexa Fluor® 488

sc-514352 AF488
200 µg/ml
$357.00

Pax 抗体 (D-7) Alexa Fluor® 546

sc-514352 AF546
200 µg/ml
$357.00

Pax 抗体 (D-7) Alexa Fluor® 594

sc-514352 AF594
200 µg/ml
$357.00

Pax 抗体 (D-7) Alexa Fluor® 647

sc-514352 AF647
200 µg/ml
$357.00

Pax 抗体 (D-7) Alexa Fluor® 680

sc-514352 AF680
200 µg/ml
$357.00

Pax 抗体 (D-7) Alexa Fluor® 790

sc-514352 AF790
200 µg/ml
$357.00

How can Pax (D-7): sc-514352 mouse monoclonal antibody be used for double or triple staining, if the other primary antibodies are also raised in mouse?

Asked by: Professor Griffin
In this case, we recommend using a directly conjugated mouse monoclonal primary antibody. This antibody is available conjugated to HRP (sc-514352 HRP), phycoerythrin (sc-514352 PE), fluoroscein (sc-514352 FITC) and AlexaFluors.
Answered by: Technical Support
Date published: 2017-02-28
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Rated 5 out of 5 by from Great IF results!IF in human ovarian cancer cell line seems very good!
Date published: 2024-02-19
Rated 5 out of 5 by from Fluorescence is very brightThis antibody stains very brightly and is applicable to horse skeletal muscle satellite cells.
Date published: 2022-11-03
Rated 3 out of 5 by from averagePaxD7, the room temperature of 25 degrees, the dilution ratio of 1:500, 0.5g TBST 10ml. with skim milk and incubated overnight, second days of development, repeated 2 times, once did not run out of band, a band out of light color, the background color is deep, it is difficult to calculate the gray value.C2C12 cell.
Date published: 2017-10-13
Rated 5 out of 5 by from Great Western blot data of Pax expressionGreat Western blot data of Pax expression in Raji and Hep G2 whole cell lysates. -SCBT QC
Date published: 2013-08-04
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Pax 抗体 (D-7) is rated 4.5 out of 5 by 4.
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