p130 Antibody (211.6): sc-9963

p130 Antibody (211.6) is a mouse monoclonal IgG1 kappa light chain antibody raised against the full-length human p130 protein, also known as RBL2 or Retinoblastoma-like protein 2. p130 monoclonal antibody (211.6) is suitable for applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and ELISA in mouse, rat, and human species. p130 protein is a crucial member of the retinoblastoma family of tumor suppressors, playing a key role in regulating the cell cycle by controlling the transition from the G1 to the S phase. p130 protein functions by forming complexes with E2F transcription factors, thereby inhibiting the expression of genes necessary for DNA synthesis and cell cycle progression. Located predominantly in the nucleus, p130 protein is essential for maintaining cellular quiescence and preventing uncontrolled cell proliferation, which is vital for tumor suppression. p130 protein is involved in chromatin remodeling and cellular differentiation, contributing to the regulation of gene expression and development. p130 monoclonal antibody (211.6) enables researchers to investigate the molecular mechanisms underlying cell cycle regulation and cancer biology, making p130 (211.6) monoclonal antibody an indispensable tool for advancing research in cell proliferation, differentiation, and cancer treatment.

The preferred p130 antibody is p130 Antibody (A-10): sc-374521.