p-Cofilin 1 Antibody (E-5): sc-271921
- p-Cofilin 1 Antibody (E-5) is a mouse monoclonal IgM κ, cited in 13 publications, provided at 200 µg/ml
- raised against a short amino acid sequence containing phosphorylated Ser 3 of Cofilin 1 of human origin
- recommended for detection of Ser 3 phosphorylated Cofilin 1 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including and bovine and porcine
- m-IgGκ BP-HRP is the preferred secondary detection reagent for p-Cofilin 1 Antibody (E-5) for WB and IHC(P) applications. This reagent is now offered in a bundle with p-Cofilin 1 Antibody (E-5) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
p-Cofilin 1 Antibody (E-5) is a mouse monoclonal IgM antibody that detects p-Cofilin 1, specifically the Ser 3 phosphorylated form, in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). p-Cofilin 1 Antibody (E-5) is available in a non-conjugated format, allowing for versatile experimental use. Cofilin, a critical actin-binding protein, plays a vital role in regulating actin cytoskeleton, which is essential for various cellular processes, including motility, division, and shape maintenance. Phosphorylation of cofilin at Serine 3 by LIM-kinase 1 (LIMK-1) inhibits actin-depolymerizing activity, thereby stabilizing actin filaments and promoting cytoskeletal integrity. This regulation allows cells to respond dynamically to signaling cues, facilitating processes such as cell migration and tissue remodeling. Cofilin′s interaction with other actin-binding proteins further underscores cofilin′s importance in maintaining the delicate balance of actin dynamics within cells, making anti-p-Cofilin 1 antibody (E-5) an invaluable tool for researchers studying cytoskeletal organization and its implications in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
p-Cofilin 1 Antibody (E-5) | sc-271921 | 200 µg/ml | $322.00 | |||
p-Cofilin 1 Antibody (E-5): m-IgGκ BP-HRP Bundle | sc-551996 | 200 µg Ab; 40 µg BP | $361.00 | |||
p-Cofilin 1 (E-5) Neutralizing Peptide | sc-271921 P | 100 µg/0.5 ml | $69.00 |