OR-486 CAS: 7659-29-2
MF: C6H4N2O6
MW: 200.11
A COMT inhibitor.

OR-486 (CAS 7659-29-2)

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同义词: 3,5-Dinitrocatechol
应用; A COMT inhibitor
CAS号码: 7659-29-2
纯度: ≥98%
分子量: 200.11
分子式: C6H4N2O6
* 参考分析证明 大量特定数据 (包括水 含量).
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OR-486 is a potent and selective catechol-O-methyl transferase inhibitor (COMT). COMT functions to methylate catecholamine neurotransmitters. OR-486 has also been shown to be a chelating reagent useful in vanadium assays.


参考文献

Borgulya et al (1989) Catechol-O-methyltransferase-inhibiting pyrocatechol derivatives: synthesis and structure-activity studies. Helv.Chim.Acta 72 952. Mannisto and Kaakola (1990) Rationale for selective COMT inhibitors as adjuncts in the drug treatment of Parkinsons disease. Pharmacol.Toxicol. 66 317.

外观 :
Powder
物理状态 :
Solid
溶解度 :
Soluble to 100 mM in Ethanol and to 100 mM in DMSO
保存 :
Store at room temperature
仅供科研使用。不可用于诊断或治疗。
PubChem CID :
3870203
SMILES :
C1=C(C=C(C(=C1[N+](=O)[O-])O)O)[N+](=O)[O-]

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