Date published: 2025-9-9

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Nop1p 抗体 (28F2): sc-57940

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说明书
  • Nop1p 抗体 28F2 是小鼠单克隆 IgG3Nop1p抗体, 在5篇文献中引用,规格为250 µl supernatant
  • 针对S. cerevisiae来源的核制剂
  • 推荐用于 S. cerevisiae 来源的Nop1p WB, IP 和 IF检测
  • 目前,我们还没有完成Nop1p 抗体 (28F2)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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関連項目

Nop1p抗体(28F2)是一种IgG3小鼠单克隆Nop1p抗体(也称为Nop1p抗体),可通过WB、IP和IF检测酿酒酵母来源的Nop1p蛋白。Nop1p抗体(28F2)可作为非偶联的抗Nop1p抗体提供。Nop1是一种在系统发育上保守的蛋白质,在核糖体生物发生过程中,通过与一类小核仁RNA的结合,对pre-rRNA的有效加工至关重要。小核仁RNA(snoRNAs)与定位于核仁的核糖核蛋白颗粒(snoRNPs)相关。Nop1(核仁蛋白1)在结构和功能上与脊椎动物原纤维蛋白同源,对生存至关重要。酿酒酵母NOP1基因编码一个位于核仁结构内的327个氨基酸的蛋白质,类似于哺乳动物核仁的致密纤维区域。酵母NOP1基因编码的蛋白质在氨基末端含有甘氨酸/精氨酸丰富的序列重复。人类原纤维蛋白可被患有硬皮病自身免疫性疾病的人类的抗血清特异性免疫沉淀。除了与小核仁RNA的结合外,NOP1对核糖体的生物发生也是必需的。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

Nop1p 抗体 (28F2) 参考文献:

  1. 人纤维蛋白的 cDNA 克隆和测序,人纤维蛋白是一种被自身免疫抗血清识别的保守核小体蛋白。  |  Aris, JP. and Blobel, G. 1991. Proc Natl Acad Sci U S A. 88: 931-5. PMID: 1846968
  2. 人类核仁蛋白纤维蛋白的进化保护及其在酵母中的功能表达  |  Jansen, RP., et al. 1991. J Cell Biol. 113: 715-29. PMID: 2026646
  3. NOP1 的分离和测序。编码与人类自身免疫抗原同源的核小体蛋白的酵母基因。  |  Henríquez, R., et al. 1990. J Biol Chem. 265: 2209-15. PMID: 2298745

订购信息

产品名称产品编号规格价格数量收藏夹

Nop1p 抗体 (28F2)

sc-57940
250 µl supernatant
$316.00

Will it detect Plasmodium falciparum Nop1 in IF ?

Asked by: Chinmoy
Thank you for your question. This antibody has not yet been tested in Plasmodium falciparum and so that is not a recommended use at this time. We are still gathering data to show on our website. Check back for updates!
Answered by: Tech Service
Date published: 2024-08-05

What is the concentration of sc-57940: Nop1p (28F2) monoclonal antibody?

Asked by: Dr Ninau Qelp
Thank you for your question. The concentration of Nop1p (28F2): sc-57940 has not been characterized. This antibody is provided as 250 µl of supernatant
Answered by: Technical Support
Date published: 2017-03-24
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Rated 4 out of 5 by from Anti-Nop1pThe antibody was well suitable for western blot analysis. Sharp bands, applicable as a control for cell fractionation experiments.
Date published: 2023-11-24
Rated 5 out of 5 by from Good for Western BlotThis antibody has been used for western blotting in published research. -SCBT QC
Date published: 2023-09-14
Rated 4 out of 5 by from Anti-Nop1We used the Anti-Nop1 as a control of cell fractionation experiments. Nop1 is only detectable in the total fraction of cell lysates. The antibody is a great choice for controlling fractionation experiments because of nice signals on the blots.
Date published: 2019-06-25
Rated 5 out of 5 by from StrongStrong, single band detected at expected molecular weight in yeast cell extract. -SCBT QC
Date published: 2015-03-12
Rated 5 out of 5 by from WB publishable data with yeast yeastWB publishable data with yeast yeast - SCBT Publication Review
Date published: 2013-10-29
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Nop1p 抗体 (28F2) is rated 4.6 out of 5 by 5.
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