NCS-382 Sodium Salt (CAS 131733-92-1)
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NCS-382 Sodium Salt is a compound that functions as a potent and selective antagonist of the N-methyl-D-aspartate (NMDA) receptor. It acts by binding to the receptor and inhibiting its activity, thereby blocking the influx of calcium ions into the cell. This mechanism of action is crucial for modulating synaptic transmission and plasticity in the central nervous system. By specifically targeting the NMDA receptor, NCS-382 Sodium Salt plays a significant role in research aimed at understanding the physiological and pathological processes involving glutamate signaling. Its ability to selectively block NMDA receptor function makes it a valuable tool for investigating the role of this receptor in various cellular and molecular processes. In experimental applications, this NCS-382 Sodium Salt′s mechanism of action allows researchers to explore signaling pathways and neuronal functions associated with NMDA receptor activity.
NCS-382 Sodium Salt (CAS 131733-92-1) References
- Anti-sedative and anti-cataleptic properties of NCS-382, a gamma-hydroxybutyrate receptor antagonist. | Schmidt, C., et al. 1991. Eur J Pharmacol. 203: 393-7. PMID: 1773824
- A specific gamma-hydroxybutyrate receptor ligand possesses both antagonistic and anticonvulsant properties. | Maitre, M., et al. 1990. J Pharmacol Exp Ther. 255: 657-63. PMID: 2173754
- Gammahydroxybutyrate (GHB) receptor ligand effects on evoked synaptic field potentials in CA1 of the rat hippocampal slice. | King, MA., et al. 1997. J Neural Transm (Vienna). 104: 1177-93. PMID: 9503264
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
NCS-382 Sodium Salt, 10 mg | sc-203444 | 10 mg | $86.00 | |||
NCS-382 Sodium Salt, 50 mg | sc-203444A | 50 mg | $374.00 |