Date published: 2025-9-8

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NCAM2 抗体 (44): sc-136328

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说明书
  • NCAM2 抗体 44 是小鼠单克隆 IgG1 κ,NCAM2抗体, 在6篇文献中引用,规格为200 µg/ml
  • 免疫mouse物种的NCAM2的氨基酸479-677
  • 推荐用于检测mouse, rat和human来源的NCAM2,由WBIP提供
  • 还可偶联琼脂糖 用于IP; 偶联HRP 用于WB, IHC(P) 和ELISA
  • 关于如何获取NCAM2 (44): sc-136328免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • 1 BP-HRP">m-IgG1 BP-HRP是NCAM2 Antibody (44) 适用于 WB 应用。 的首选辅助检测试剂。该试剂现与NCAM2 Antibody (44) 打包提供(请参阅下面的订购信息)。

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関連項目

NCAM2 Antibody(44)是一种IgG1 κ小鼠单克隆NCAM2抗体(也称为NCAM2抗体,或神经细胞黏附分子2抗体),通过WB 和 IP检测小鼠、大鼠和人类来源的NCAM2蛋白。NCAM2 Antibody(44)既可以是非偶联的抗NCAM2抗体形式,也可以是多种偶联的抗NCAM2抗体形式,包括琼脂糖、辣根过氧化物酶。NCAM2 (neural cell adhesion molecule 2)是由人类基因NCAM2编码的一种837个氨基酸组成的蛋白质。NCAM2包含5个免疫球蛋白样结构域、2个纤维连接蛋白ⅲ结构域、1个跨膜结构域和1个胞质结构域。该基因在人类成年和胎儿大脑中表达最强。NCAM2是神经细胞黏附分子(NCAM)家族的成员。ncam是一种与细胞表面糖蛋白密切相关的糖蛋白,参与生长过程中细胞与细胞之间的相互作用,在胚胎发生和发育中发挥重要作用。NCAM2被认为是参与某些唐氏综合征表型的一个很好的候选者,因为NCAMs的轻微过度表达增加了许多倍的同型细胞粘附特性。在体内,Stat5通过与NKL自然杀伤细胞系中NCAM2内含子结合来调控NCAM2;这种结合是由激活Stat5的细胞因子诱导的。尽管Stat1和Stat3与Stat5有相同的结合序列,但它们都不与该区域结合。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

NCAM2 抗体 (44) 参考文献:

  1. 使用针对神经内分泌相关抗原的单克隆抗体(RNL-1)对无胸腺小鼠体内的人类小细胞肺癌异种移植物进行免疫定位。  |  Mijnheere, EP., et al. 1991. Br J Cancer Suppl. 14: 78-81. PMID: 1645579
  2. 针对神经细胞粘附分子(NCAM)的单克隆抗体(RNL-1)在携带人类小细胞肺癌异种移植物的无胸腺小鼠中的生物分布。  |  Boerman, OC., et al. 1991. Int J Cancer. 48: 457-62. PMID: 1645701
  3. 多发性骨髓瘤中的浆细胞表达一种自然杀伤细胞缔合作用抗原:CD56(NKH-1;Leu-19)。  |  Van Camp, B., et al. 1990. Blood. 76: 377-82. PMID: 1695113
  4. 神经内分泌恶性肿瘤特有的新型抗原。  |  Broers, JL., et al. 1991. Cancer. 67: 619-33. PMID: 1845952
  5. 人神经外胚层肿瘤上神经细胞黏合剂分子同工型和 L1 黏附分子的差异表达谱。  |  Figarella-Branger, DF., et al. 1990. Cancer Res. 50: 6364-70. PMID: 2400996
  6. Leu-19(CD56)白细胞分化抗原和神经细胞粘附分子的特性。  |  Lanier, LL., et al. 1989. J Exp Med. 169: 2233-8. PMID: 2471777
  7. 显示神经内分泌分化特征的非小细胞肺癌肿瘤的临床特征。  |  Berendsen, HH., et al. 1989. J Clin Oncol. 7: 1614-20. PMID: 2553880
  8. 利用针对神经内分泌分化抗原的单克隆抗体检测骨髓抽吸物中的小细胞肺癌转移灶。  |  Berendsen, HH., et al. 1988. J Clin Pathol. 41: 273-6. PMID: 2834417
  9. 对支气管镜下获取的肺癌标本同时进行标准光学显微镜检查和免疫组织学检查。  |  Berendsen, HH., et al. 1988. Eur J Cancer Clin Oncol. 24: 915-21. PMID: 2844544
  10. 源自肺小细胞癌的三种新型变异细胞系的特征。  |  de Leij, L., et al. 1985. Cancer Res. 45: 6024-33. PMID: 2998591

订购信息

产品名称产品编号规格价格数量收藏夹

NCAM2 抗体 (44)

sc-136328
200 µg/ml
$316.00

NCAM2 (44): m-IgG1 BP-HRP 套装

sc-531665
200 µg Ab; 20 µg BP
$354.00

NCAM2 抗体 (44) AC

sc-136328 AC
500 µg/ml, 25% agarose
$416.00

NCAM2 抗体 (44) HRP

sc-136328 HRP
200 µg/ml
$316.00

Are there any issues with using sc-136328: NCAM2 (44) mouse monoclonal primary antibody on mouse samples?

Asked by: Germaine
Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent,we recommend using a directly conjugated primary antibody. Please contact our special orders department for pricing and availability of sc-136328 conjugates.
Answered by: Technical Support
Date published: 2018-01-31
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Rated 5 out of 5 by from Working greatWe used this antibody for characterizing proteolysis of NCAM2 in cell and mouse brain. It works great to investigate the levels of NCAM2.
Date published: 2021-04-15
Rated 5 out of 5 by from Working great!I used this antibody to characterize the proteolysis of NCAM2. It was working great in mouse and human brain for Western blot.
Date published: 2021-04-15
Rated 5 out of 5 by from Detects Glycosylated NCAM2This antibody shows good detection of the high MW, glycosylated form of NCAM2 in rat brain tissue extract in Western Blot.
Date published: 2017-02-02
Rated 5 out of 5 by from Robust band present in western blot analysisRobust band present in western blot analysis of NCAM2 expression in rat brain tissue extract. -SCBT QC
Date published: 2014-03-24
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NCAM2 抗体 (44) is rated 5.0 out of 5 by 4.
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