Date published: 2026-4-24

1-800-457-3801

SCBT Portrait Logo
Seach Input

N6-2-(4-Aminophenyl)ethyladenosine (CAS 89705-21-5)

0.0(0)
Write a reviewAsk a question

Alternate Names:
N-[2-(4-Aminophenyl)ethyl]-adenosine
CAS Number:
89705-21-5
Purity:
≥95%
Molecular Weight:
386.41
Molecular Formula:
C18H22N6O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

A potent, non-selective A3 adenosine receptor agonist.


N6-2-(4-Aminophenyl)ethyladenosine (CAS 89705-21-5) References

  1. N6-2-(4-aminophenyl)ethyladenosine (APNEA), a putative adenosine A3 receptor agonist, enhances methamphetamine-induced dopamine outflow in rat striatum.  |  Gołembiowska, K. and Zylewska, A. 1998. Pol J Pharmacol. 50: 299-305. PMID: 10091714
  2. The adenosine receptor agonist, APNEA, increases calcium influx into rat cortical synaptosomes through N-type channels associated with A2a receptors.  |  Li, SN. and Wong, PT. 2000. Neurochem Res. 25: 457-9. PMID: 10823578
  3. Adenosine A3 receptor-mediated airway microvascular leakage: role of mast cells and tachykinins.  |  Nagano, Y., et al. 2000. Res Commun Mol Pathol Pharmacol. 108: 96-107. PMID: 11758979
  4. Photomodulation of G protein-coupled adenosine receptors by a novel light-switchable ligand.  |  Bahamonde, MI., et al. 2014. Bioconjug Chem. 25: 1847-54. PMID: 25248077
  5. Chloride channel blocker IAA-94 increases myocardial infarction by reducing calcium retention capacity of the cardiac mitochondria.  |  Ponnalagu, D., et al. 2019. Life Sci. 235: 116841. PMID: 31494173
  6. Molecular probes for the human adenosine receptors.  |  Yang, X., et al. 2021. Purinergic Signal. 17: 85-108. PMID: 33313997
  7. Contribution of Lipids to the Flavor of Mussel (Mytilus edulis) Maillard Reaction Products.  |  Xin, R., et al. 2022. Foods. 11: PMID: 36230091
  8. Adenosine A3 receptors: two into one won't go.  |  Carruthers, AM. and Fozard, JR. 1993. Trends Pharmacol Sci. 14: 290-1. PMID: 8249145
  9. Adenosine receptor subtypes.  |  Collis, MG. and Hourani, SM. 1993. Trends Pharmacol Sci. 14: 360-6. PMID: 8296392
  10. Adenosine A3 receptors mediate hypotension in the angiotensin II-supported circulation of the pithed rat.  |  Fozard, JR. and Carruthers, AM. 1993. Br J Pharmacol. 109: 3-5. PMID: 8495245
  11. In vivo role of the adenosine A3 receptor: N6-2-(4-aminophenyl)ethyladenosine induces bronchospasm in BDE rats by a neurally mediated mechanism involving cells resembling mast cells.  |  Meade, CJ., et al. 1996. J Pharmacol Exp Ther. 279: 1148-56. PMID: 8968336
  12. The role of A3 adenosine receptors in central regulation of arterial blood pressure.  |  Stella, L., et al. 1998. Br J Pharmacol. 125: 437-40. PMID: 9806324
  13. Differential effects of adenosine receptor subtypes on release and reuptake of hippocampal serotonin.  |  Okada, M., et al. 1999. Eur J Neurosci. 11: 1-9. PMID: 9987006

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

N6-2-(4-Aminophenyl)ethyladenosine, 25 mg

sc-253170
25 mg
$81.00