Molecular structure of Montelukast Sulfoxide(Mixture of Diastereomers), CAS Number: 909849-96-3
Montelukast Sulfoxide(Mixture of Diastereomers) (CAS 909849-96-3)
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Alternate Names:
1-[[[1-[3-[2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]sulfinyl]methyl]cyclopropaneacetic Acid
Application:
Montelukast Sulfoxide(Mixture of Diastereomers) is A Montelukast metabolite
CAS Number:
909849-96-3
Molecular Weight:
602.18
Molecular Formula:
C35H36ClNO4S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Montelukast Sulfoxide(Mixture of Diastereomers) is a metabolite of the leukotriene LTD4 receptor antagonist Montelukast (sc-202231). The thioether group of Montelukast is oxidized to the sulfoxide in this analog. This preparation of Montelukast Sulfoxide is a mixture of possible diastereomers.
Montelukast Sulfoxide(Mixture of Diastereomers) (CAS 909849-96-3) References
- Metabolism of thioridazine by microsomal monooxygenases: relative roles of P450 and flavin-containing monooxygenase. | Blake, BL., et al. 1995. Xenobiotica. 25: 377-93. PMID: 7645304
- Translocation of both lysosomal LDL-derived cholesterol and plasma membrane cholesterol to the endoplasmic reticulum for esterification may require common cellular factors involved in cholesterol egress from the acidic compartments (lysosomes/endosomes). | Spillane, DM., et al. 1995. Biochim Biophys Acta. 1254: 283-94. PMID: 7857968
- Role of flavin-dependent monooxygenases and cytochrome P450 enzymes in the sulfoxidation of S-methyl N,N-diethylthiolcarbamate. | Madan, A., et al. 1993. Biochem Pharmacol. 46: 2291-7. PMID: 8274163
- Role of cytochrome P450 3A4 in human metabolism of MK-639, a potent human immunodeficiency virus protease inhibitor. | Chiba, M., et al. 1996. Drug Metab Dispos. 24: 307-14. PMID: 8820421
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| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Montelukast Sulfoxide(Mixture of Diastereomers), 5 mg | sc-211926 | 5 mg | $330.00 |