Date published: 2025-9-7

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LZTR1 抗体 (E-12): sc-390166

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说明书
  • LZTR1 抗体 E-12 是小鼠单克隆 IgG1 κ,LZTR1抗体, 在11篇文献中引用,规格为200 µg/ml
  • 与human起源的LZTR1的N-terminus附近的肽图谱
  • LZTR1 抗体 (E-12) 推荐用于 WB, IP, IF 和 ELISA,检测mouse, rat 和human 来源的 LZTR1; 也和以下物种反应,包括: 和 equine, canine, bovine and porcine
  • 可用于ChIP的TransCruz试剂(sc-390166 X, 200 µg/0.1 ml)
  • 抗LZTR1抗体(E-12)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取LZTR1 (E-12): sc-390166免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • 1 BP-HRP">m-IgG1 BP-HRP是LZTR1 Antibody (E-12) 适用于 WB 应用。 的首选辅助检测试剂。该试剂现与LZTR1 Antibody (E-12) 打包提供(请参阅下面的订购信息)。

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関連項目

LZTR1抗体(E-12)是一种IgG1 κ小鼠单克隆LZTR1抗体(也称为LZTR1抗体),它通过WB、IP、IF和ELISA检测小鼠、大鼠和人类的LZTR1蛋白。LZTR1抗体(E-12)既提供非偶联形式的抗LZTR1抗体,也提供多种偶联形式的抗LZTR1抗体,包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。LZTR1,即亮氨酸拉链样转录调节因子1,是BTB-kelch超家族的一个成员。LZTR1包含两个BTB(POZ)结构域和六个Kelch重复序列。BTB(Broad-Complex、Tramtrack和Bric-a-brac)结构域,也被称为POZ(POxvirus和Zinc finger)结构域,是一个包含多个Kelch重复序列和/或C2H2型锌指的N端同源二聚体结构域。含有BTB结构域的蛋白质被认为通过控制染色质结构和功能参与转录调控。LZTR1被认为在胚胎发育过程中起转录调节因子的作用。LZTR1在胎儿大脑、心脏、肾脏、肝脏和肺部中表达,并全部位于高尔基网络的细胞质表面。LZTR1基因位于与该疾病相关的染色体缺失区域内,因此LZTR1很可能与心面综合征/DiGeorge综合征的病因有关。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

LZTR1 抗体 (E-12) 参考文献:

  1. 绘制蛋白质组尺度的人类蛋白质-蛋白质相互作用网络图。  |  Rual, JF., et al. 2005. Nature. 437: 1173-8. PMID: 16189514
  2. BTB-kelch蛋白LZTR-1是一种新型高尔基体蛋白,在诱导细胞凋亡时会被降解。  |  Nacak, TG., et al. 2006. J Biol Chem. 281: 5065-71. PMID: 16356934
  3. 迪乔治综合症  |  Dodson, WE., et al. 1969. Lancet. 1: 574-5. PMID: 4179863
  4. 隐性遗传的遗传性多中心骨溶解症:一种新的综合征。  |  Torg, JS., et al. 1969. J Pediatr. 75: 243-52. PMID: 5795345
  5. BTB 结构域主要存在于锌指蛋白中,它定义了一个进化保守的家族,其中包括果蝇的几个发育调控基因。  |  Zollman, S., et al. 1994. Proc Natl Acad Sci U S A. 91: 10717-21. PMID: 7938017
  6. POZ 结构域:一种保守的蛋白质-蛋白质相互作用结构域。  |  Bardwell, VJ. and Treisman, R. 1994. Genes Dev. 8: 1664-77. PMID: 7958847
  7. PLZF BTB 结构域的晶体结构。  |  Ahmad, KF., et al. 1998. Proc Natl Acad Sci U S A. 95: 12123-8. PMID: 9770450

订购信息

产品名称产品编号规格价格数量收藏夹

LZTR1 抗体 (E-12)

sc-390166
200 µg/ml
$316.00

LZTR1 (E-12): m-IgG1 BP-HRP 套装

sc-531735
200 µg Ab; 20 µg BP
$354.00

LZTR1 抗体 (E-12) X

sc-390166 X
200 µg/0.1 ml
$316.00

LZTR1 抗体 (E-12) AC

sc-390166 AC
500 µg/ml, 25% agarose
$416.00

LZTR1 抗体 (E-12) HRP

sc-390166 HRP
200 µg/ml
$316.00

LZTR1 抗体 (E-12) FITC

sc-390166 FITC
200 µg/ml
$330.00

LZTR1 抗体 (E-12) PE

sc-390166 PE
200 µg/ml
$343.00

LZTR1 抗体 (E-12) Alexa Fluor® 488

sc-390166 AF488
200 µg/ml
$357.00

LZTR1 抗体 (E-12) Alexa Fluor® 546

sc-390166 AF546
200 µg/ml
$357.00

LZTR1 抗体 (E-12) Alexa Fluor® 594

sc-390166 AF594
200 µg/ml
$357.00

LZTR1 抗体 (E-12) Alexa Fluor® 647

sc-390166 AF647
200 µg/ml
$357.00

LZTR1 抗体 (E-12) Alexa Fluor® 680

sc-390166 AF680
200 µg/ml
$357.00

LZTR1 抗体 (E-12) Alexa Fluor® 790

sc-390166 AF790
200 µg/ml
$357.00

LZTR1 (E-12) 中和勝肽

sc-390166 P
100 µg/0.5 ml
$68.00

Can you confirm where the approximate immunogen/ epitope is in protein? eg n- or c- terminus

Asked by: Alex
Thank you for your question. LZTR1 Antibody (E-12): sc-390166 was raised against a peptide mapping near the N-terminus of LZTR1 of human origin.
Answered by: Tech Support Europe
Date published: 2024-04-19

Does this antibody recognize the Drosophila ortholog CG3711? 

Asked by: JackieG
Thank you for your question. Please contact our Technical Service Department and we would be happy to help you perform sequence analysis on the antibody's antigen to predict any potential cross-reactivity with drosophila. At this time, the antibody has not been tested in that species, nor are we aware of any publications using the antibody in that species.
Answered by: Technical Support
Date published: 2018-12-03

What application is the blocking peptide sc-390166 P appropriate for?

Asked by: TinTin
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-24
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Rated 5 out of 5 by from Clear band around 90kd1:500 in 5% milk workes well in Hela cells, including two wild type and two LZTR1 knockout clones. A non-specific band at 130kd is noticed.
Date published: 2019-12-16
Rated 4 out of 5 by from Good in IBIB performed in HEK293T cells, RIPA buffer lysis, 1:250 dilution in 5 %BSA.
Date published: 2018-02-22
Rated 4 out of 5 by from Antibody appears specific and cleanIn Western blot using a 293T cell lysate this antibody exhibits a sharp band at the expected molecular weight. Not additional non-specific bands are observed.
Date published: 2017-06-14
Rated 5 out of 5 by from Produced positive Western Blot data of LZTR1Produced positive Western Blot data of LZTR1 expression in KNRK and WI 38 whole cell lysates. -SCBT QC
Date published: 2013-07-06
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LZTR1 抗体 (E-12) is rated 4.5 out of 5 by 4.
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