Date published: 2025-9-8

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LCOR 抗体 (C-4): sc-398636

5.0(1)
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说明书
  • LCOR抗体(C-4)是小鼠单克隆IgM (kappa轻链),规格为200 µg/ml
  • 特异性抗原位于human物种的LCOR的内部区域内的氨基酸291-334之间
  • 推荐用于 mouse, rat, human 和 avian 来源的LCOR WB, IP, IF 和 ELISA检测; 也和以下物种反应,包括: 和 equine, canine, porcine and avian
  • 目前,我们还没有完成LCOR 抗体 (C-4)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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    関連項目

    LCOR(配体依赖性共抑制因子),也被称为MLR2,是一个包含433个氨基酸的转录共抑制因子,具有一个LXXLL基序、一个核定位信号和一个螺旋-环-螺旋结构域。LCOR在胎儿和成人组织中广泛表达,并通过其LXXLL基序被招募到核受体。在雌二醇存在的情况下,LCOR与几种雌激素受体相互作用,如ERα和ERβ。此外,LCOR作为分子支架,招募参与转录抑制的蛋白质到DNA。LCOR的活性以受体依赖性的方式被HDAC(组蛋白去乙酰化酶)抑制剂曲古抑菌素A所抑制,这表明其依赖于HDAC的作用模式。LCOR在一个负反馈环中发挥作用,以减少激素诱导的反式激活。

    仅限研究使用。不适用于诊断和治疗用途。

    订购信息

    产品名称产品编号规格价格数量收藏夹

    LCOR 抗体 (C-4)

    sc-398636
    200 µg/ml
    $316.00

    LCOR (C-4) 中和勝肽

    sc-398636 P
    100 µg/0.5 ml
    $68.00

    What application is the blocking peptide sc-398636 P appropriate for?

    Asked by: DefinitelyNotMatt
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Answered by: Technical Support
    Date published: 2017-03-01
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    Rated 5 out of 5 by from Produced positive Western blot data of LCORProduced positive Western blot data of LCOR expression in non-transfected and human LCOR transfected 293T whole cell lysates. -SCBT QC
    Date published: 2014-11-30
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    LCOR 抗体 (C-4) is rated 5.0 out of 5 by 1.
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