Date published: 2025-9-8

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L-FABP 抗体 (C-4): sc-374537

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说明书
  • L-FABP抗体(C-4)是小鼠单克隆IgG2a κ, 在5篇文献中引用,规格为200 µg/ml
  • 免疫原氨基酸序列7-126位于human物种的L-FABP的内部区域内
  • 抗-L-FABP 抗体 (C-4) 推荐用于 WB, IP, IF, IHC(P) 和 ELISA,检测mouse, rat 和human 来源的 L-FABP
  • 抗L-FABP抗体(C-4)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取L-FABP (C-4): sc-374537免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRPm-IgG2a BP-HRP 是 L-FABP 抗体 (C-4) 在 WB and IHC(P) 应用中的首选二抗检测试剂。这些试剂现与L-FABP 抗体 (C-4) 组合成套装提供。 (请参阅下面的订购信息)。

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関連項目

L-FABP抗体(C-4)是一种IgG2a κ小鼠单克隆L-FABP抗体,可通过WB、IP、IF、IHC(P)和ELISA检测小鼠、大鼠和人类的L-FABP。L-FABP抗体(C-4)既可作为非偶联的抗L-FABP抗体形式,也可作为多种偶联形式的抗L-FABP抗体,包括琼脂糖、HRP、PE、FITC和多种Alexa Fluor®偶联物。脂肪酸结合蛋白,即FABPs,是一组同源细胞质蛋白,它们以高度组织特异性的方式表达,并在脂质和碳水化合物代谢平衡中发挥不可或缺的作用。FABPs在各自的组织中介导脂肪酸(FA)和/或疏水性配体的摄取、转运和定位。这些作用背后的机制可以产生FA的被动扩散摄取和蛋白质介导的跨膜转运。FABPs在脂肪细胞(A-FABP)、大脑(B-FABP)、表皮(E-FABP,也称为银屑病相关FABP或PA-FABP)、肌肉和心脏(H-FABP,也称为乳腺源性生长抑制剂或MDGI)、肠道(I-FABP)、肝脏(L-FABP)、髓磷脂(M-FABP)和睾丸(T-FABP)中表达。肝脏特异性FABP(L-FABP)的表达受发育、激素、饮食和药理学因素的调节,是胆固醇合成和代谢所必需的。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

L-FABP 抗体 (C-4) 参考文献:

  1. 脂肪酸结合蛋白的脂肪酸转运功能。  |  Storch, J. and Thumser, AE. 2000. Biochim Biophys Acta. 1486: 28-44. PMID: 10856711
  2. 揭示细胞脂肪酸结合蛋白的意义。  |  Glatz, JF. and Storch, J. 2001. Curr Opin Lipidol. 12: 267-74. PMID: 11353329
  3. 神经组织的脂肪酸结合蛋白  |  Veerkamp, JH. and Zimmerman, AW. 2001. J Mol Neurosci. 16: 133-42; discussion 151-7. PMID: 11478368
  4. 对 4-HNE 修饰的 L-FABP 的表征揭示了其结构和功能动态的改变。  |  Smathers, RL., et al. 2012. PLoS One. 7: e38459. PMID: 22701647
  5. L-FABP 和葡萄糖对多不饱和脂肪酸诱导 PPARα-regulated β-oxidative enzymes 的影响。  |  Petrescu, AD., et al. 2013. Am J Physiol Gastrointest Liver Physiol. 304: G241-56. PMID: 23238934
  6. L-FABP-/- 小鼠对早期酒精肝氧化应激的易感性。  |  Smathers, RL., et al. 2013. J Lipid Res. 54: 1335-45. PMID: 23359610
  7. 尿液 L-FABP 预测早期急性肾损伤重症患者的不良预后。  |  Parr, SK., et al. 2015. Kidney Int. 87: 640-8. PMID: 25229339
  8. 利用表面增强拉曼光谱快速、超灵敏地检测急性肾损伤生物标志物 CH3L1 和 L-FABP。  |  Wang, L., et al. 2023. Spectrochim Acta A Mol Biomol Spectrosc. 295: 122604. PMID: 36947940
  9. 细胞质脂肪酸结合蛋白:它们的结构和基因。  |  Veerkamp, JH. and Maatman, RG. 1995. Prog Lipid Res. 34: 17-52. PMID: 7644552
  10. 肝脏脂肪酸结合蛋白的调节机制。  |  Kaikaus, RM., et al. Mol Cell Biochem. 123: 93-100. PMID: 8232272
  11. 通过脂肪细胞脂肪酸结合蛋白 aP2 的靶向突变使肥胖与胰岛素抵抗脱钩。  |  Hotamisligil, GS., et al. 1996. Science. 274: 1377-9. PMID: 8910278
  12. L-FABP 和 I-FABP 的表达可增加 L 细胞对 NBD-硬脂酸盐的吸收和胞质扩散。  |  Murphy, EJ. 1998. Am J Physiol. 275: G244-9. PMID: 9688651

订购信息

产品名称产品编号规格价格数量收藏夹

L-FABP 抗体 (C-4)

sc-374537
200 µg/ml
$316.00

L-FABP (C-4): m-IgG Fc BP-HRP 套装

sc-525978
200 µg Ab; 10 µg BP
$354.00

L-FABP (C-4): m-IgG2a BP-HRP 套装

sc-546474
200 µg Ab; 10 µg BP
$354.00

L-FABP 抗体 (C-4) AC

sc-374537 AC
500 µg/ml, 25% agarose
$416.00

L-FABP 抗体 (C-4) HRP

sc-374537 HRP
200 µg/ml
$316.00

L-FABP 抗体 (C-4) FITC

sc-374537 FITC
200 µg/ml
$330.00

L-FABP 抗体 (C-4) PE

sc-374537 PE
200 µg/ml
$343.00

L-FABP 抗体 (C-4) Alexa Fluor® 488

sc-374537 AF488
200 µg/ml
$357.00

L-FABP 抗体 (C-4) Alexa Fluor® 546

sc-374537 AF546
200 µg/ml
$357.00

L-FABP 抗体 (C-4) Alexa Fluor® 594

sc-374537 AF594
200 µg/ml
$357.00

L-FABP 抗体 (C-4) Alexa Fluor® 647

sc-374537 AF647
200 µg/ml
$357.00

L-FABP 抗体 (C-4) Alexa Fluor® 680

sc-374537 AF680
200 µg/ml
$357.00

L-FABP 抗体 (C-4) Alexa Fluor® 790

sc-374537 AF790
200 µg/ml
$357.00

I am using L-FABP (C-4): sc-374537 monoclonal antibody to stain paraffin embedded tissue. Do you recommend antigen retrieval when using this antibody?

Asked by: Trav11
We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
Answered by: Technical Support
Date published: 2018-03-15
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Rated 5 out of 5 by from ottimo anticorpoHo usato quest'anticorpo per fare WB con una diluizione 1:500 e mi sono trovata molto bene, segnale ottimo e pulito.
Date published: 2025-02-14
Rated 5 out of 5 by from Good AntibodyThis antibody has been used successfully to detect WB in rat small intestine samples. Specific bands were obtained with 15ug protein, 1:1000, and secondary antibody 1:5000
Date published: 2022-11-08
Rated 5 out of 5 by from L-FABP Ab for IFExcellent antibody to detect L-FABP positive cells in intestinal sections of mouse and human samples Dilution 1:1000
Date published: 2021-03-23
Rated 4 out of 5 by from LFABP (C4)I validated this clone for our laboratory. It is working great at a 1:200 titration on liver.
Date published: 2018-04-16
Rated 5 out of 5 by from Works for mouse liver - WBLiver homogenates from mouse (C57BL6) showed a single band in the expected size using standard protocols for Western blot (30ug samples, TBST-milk, 1:1000 primary ab, 1:10000 secondary ab). Clear and nice results!
Date published: 2018-03-17
Rated 5 out of 5 by from Great product!The L-FABP Antibody (C-4): sc-374537 provides great data when performing IHC with formalin fixed, paraffin-embedded tissue sections, showing strong staining localized to the cytoplasm.
Date published: 2017-01-25
Rated 5 out of 5 by from Produced excellent immunoperoxidase cytoplasmicProduced excellent immunoperoxidase cytoplasmic staining in formalin fixed, paraffin-embedded human colon tissue. -SCBT QC
Date published: 2015-04-21
Rated 5 out of 5 by from Good Western Blot data of LGood Western Blot data of L-FABP expression in non-transfected and mouse L-FABP transfected 293T whole cell lysates. -SCBT QC
Date published: 2013-11-11
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L-FABP 抗体 (C-4) is rated 4.9 out of 5 by 8.
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