Date published: 2025-9-7

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JMJD8 抗体 (H-4): sc-515520

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说明书
  • JMJD8 抗体 H-4 是小鼠单克隆 IgG2b κ,JMJD8抗体, 在7篇文献中引用,规格为200 µg/ml
  • 特异性抗原位于human物种的JMJD8的内部区域内的氨基酸192-216之间
  • JMJD8 抗体 (H-4) 推荐用于 WB, IP, IF 和 ELISA,检测mouse, rat 和human 来源的 JMJD8
  • 抗JMJD8抗体(H-4)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取JMJD8 (H-4): sc-515520免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • 2b BP-HRP">m-IgG2b BP-HRPm-IgGκ BP-HRP是JMJD8 Antibody (H-4) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与JMJD8 Antibody (H-4) 打包提供(请参阅下面的订购信息)。

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関連項目

JMJD8抗体(H-4)是一种小鼠单克隆IgG2b kappa轻链抗体,可通过蛋白质印迹(WB)、免疫沉淀(IP)、免疫荧光(IF)和酶联免疫吸附测定(ELISA)检测小鼠、大鼠和人类来源的JMJD8蛋白。抗JMJD8抗体(H-4)有非结合型和多种结合型,包括琼脂糖、辣根过氧化物酶(HRP)、藻红蛋白(PE)、异硫氰酸荧光素(FITC)和多种Alexa Fluor®结合物。JMJD8,又称含Jumonji结构域蛋白8,由334个氨基酸组成,具有一个Jumonji结构域,这是其作为组蛋白脱甲基酶的关键。这种酶活性对于基因表达的调节至关重要,因为JMJD8会修饰组蛋白,从而影响染色质结构和可及性,进而影响细胞分化、发育等过程。JMJD8位于人类第16号染色体上,该区域与多种遗传疾病有关,包括巨轴索神经病和鲁宾斯坦-塔比综合征,这凸显了JMJD8在维持正常细胞功能方面的重要性,以及其在疾病中的潜在影响。使用JMJD8单克隆抗体(H-4)使研究人员能够深入了解基因表达的调节机制以及组蛋白修饰在健康和疾病中的作用。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

JMJD8 抗体 (H-4) 参考文献:

  1. 巨轴突性神经病基因在染色体 16q24.1 上的同源性图谱。  |  Ben Hamida, C., et al. 1997. Neurogenetics. 1: 129-33. PMID: 10732815
  2. 控制实验性自身免疫性脑脊髓炎发展和淋巴细胞亚群比例的新数量性状基因位点  |  Karlsson, J., et al. 2003. J Immunol. 170: 1019-26. PMID: 12517969
  3. 系统性红斑狼疮全基因组关联研究的元分析。  |  Forabosco, P., et al. 2006. Genes Immun. 7: 609-14. PMID: 16971955
  4. 巨型轴索神经病  |  Yang, Y., et al. 2007. Cell Mol Life Sci. 64: 601-9. PMID: 17256086
  5. 巨轴索神经病(GAN)患者的基因型-表型分析。  |  Koop, O., et al. 2007. Neuromuscul Disord. 17: 624-30. PMID: 17587580
  6. 结节体Nod1 和 Nod2 控制细菌感染和炎症。  |  Tattoli, I., et al. 2007. Semin Immunopathol. 29: 289-301. PMID: 17690884
  7. 人类 NOD2 (CARD15) 基因新型启动子和第一外显子的鉴定, 进化和关联研究。  |  King, K., et al. 2007. Genomics. 90: 493-501. PMID: 17719742
  8. 鲁宾斯坦-泰比综合征(Rubinstein-Taybi Syndrome)患者中高频率的镶嵌式 CREBBP 缺失以及体细胞和种系断裂点图谱。  |  Gervasini, C., et al. 2007. Genomics. 90: 567-73. PMID: 17855048
  9. 先天性免疫和炎症性疾病中的类节点受体  |  Carneiro, LA., et al. 2007. Ann Med. 39: 581-93. PMID: 18038361

订购信息

产品名称产品编号规格价格数量收藏夹

JMJD8 抗体 (H-4)

sc-515520
200 µg/ml
$316.00

JMJD8 (H-4): m-IgGκ BP-HRP 套装

sc-525081
200 µg Ab, 40 µg BP
$354.00

JMJD8 (H-4): m-IgG2b BP-HRP 套装

sc-549210
200 µg Ab; 10 µg BP
$354.00

JMJD8 抗体 (H-4) AC

sc-515520 AC
500 µg/ml, 25% agarose
$416.00

JMJD8 抗体 (H-4) HRP

sc-515520 HRP
200 µg/ml
$316.00

JMJD8 抗体 (H-4) FITC

sc-515520 FITC
200 µg/ml
$330.00

JMJD8 抗体 (H-4) PE

sc-515520 PE
200 µg/ml
$343.00

JMJD8 抗体 (H-4) Alexa Fluor® 488

sc-515520 AF488
200 µg/ml
$357.00

JMJD8 抗体 (H-4) Alexa Fluor® 546

sc-515520 AF546
200 µg/ml
$357.00

JMJD8 抗体 (H-4) Alexa Fluor® 594

sc-515520 AF594
200 µg/ml
$357.00

JMJD8 抗体 (H-4) Alexa Fluor® 647

sc-515520 AF647
200 µg/ml
$357.00

JMJD8 抗体 (H-4) Alexa Fluor® 680

sc-515520 AF680
200 µg/ml
$357.00

JMJD8 抗体 (H-4) Alexa Fluor® 790

sc-515520 AF790
200 µg/ml
$357.00

JMJD8 (H-4) 中和勝肽

sc-515520 P
100 µg/0.5 ml
$68.00

What application is the blocking peptide sc-515520 P appropriate for?

Asked by: TinTin
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-28
  • y_2025, m_8, d_27, h_5CST
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Rated 4 out of 5 by from JMJD8 AntibodyJMJD8 is a reliable antibody that gives a good signal both in immunofluorescence and flow cytometry.
Date published: 2024-02-26
Rated 5 out of 5 by from Good for Western BlotAntibody works for Western blot with H1299 cell lysate in published research. -SCBT QC
Date published: 2023-09-14
Rated 5 out of 5 by from Excellent in Western BlottingDilution 1:1000 Western blotting on CFBE lysate cells Very strong and specific band at the expected molecular weight
Date published: 2019-12-11
Rated 5 out of 5 by from Works well for Western in SKOV3 cellsI used this antibody in ovarian cancer. Great signal for WB. (Dilution used 1/400)
Date published: 2018-11-22
Rated 5 out of 5 by from Works great for Kaiso overxpressing cellsWe tried both 293Ts that overexpress Jmjd8 and tissue expression. This antibody worked great for both.
Date published: 2017-11-02
Rated 5 out of 5 by from Great resultsTried this antibody in WB at 1:100 for cancer cell lines. Results were good and a regular size of this Ab was ordered. Hope it will perform as well as the trial size.
Date published: 2017-04-10
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JMJD8抗体 (H-4) is rated 4.8 out of 5 by 6.
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