JAK3 Inhibitor IV (CAS 58753-54-1)
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JAK3 Inhibitor IV functions as a selective inhibitor of Janus kinase 3 (JAK3). It exerts its mechanism of action by binding to the ATP-binding site of JAK3, thereby preventing the phosphorylation and activation of the enzyme. This inhibition ultimately leads to the suppression of downstream signaling pathways involved in immune cell activation and proliferation. By targeting JAK3, JAK3 Inhibitor IV has the ability to modulate immune responses and has been utilized in various experimental applications to investigate the role of JAK3 in immune-related processes. Its mechanism of action at the molecular level involves disrupting the kinase activity of JAK3, which is for the transmission of signals from cytokine receptors. Jak3 Inhibitor Iv′s ability to selectively inhibit JAK3 may be valuable for studying the function of this enzyme in immune cell signaling pathways.
JAK3 Inhibitor IV (CAS 58753-54-1) References
- Role of Janus-Kinases in Major Depressive Disorder. | Gulbins, A., et al. 2016. Neurosignals. 24: 71-80. PMID: 27487096
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
JAK3 Inhibitor IV, 10 mg | sc-295217 | 10 mg | $431.00 |