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Isoprinosine (CAS 36703-88-5)

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Alternate Names:
imunovir
Application:
Isoprinosine is an antiviral reagent
CAS Number:
36703-88-5
Molecular Weight:
1115.24
Molecular Formula:
C10H12N4O53C5H13NO•3C9H9NO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Isoprinosine functions as an immunostimulant by modulating the immune response. It acts by enhancing the activity of T-lymphocytes and killer cells. Isoprinosine also increases the production of interferon, a protein that helps to fight against viral infections. At the molecular level, Isoprinosine works by promoting the proliferation and activation of immune cells, leading to a more robust immune response.


Isoprinosine (CAS 36703-88-5) References

  1. Isoprinosine in the treatment of chronic active hepatitis type B.  |  Cianciara, J., et al. 1990. Scand J Infect Dis. 22: 645-8. PMID: 1704640
  2. Isoprinosine enhances the activation of sensitized lymphocytes by Epstein-Barr virus antigens.  |  Sundar, SK., et al. 1985. Int J Immunopharmacol. 7: 187-92. PMID: 2409036
  3. Isoprinosine abolishes the blocking factor-mediated inhibition of lymphocyte responses to Epstein-Barr virus antigens and phytohemagglutinin.  |  Sundar, SK. and Menezes, J. 1986. Int J Immunopharmacol. 8: 101-6. PMID: 2420730
  4. Effect of isoprinosine on sialylation of interleukin-2.  |  Tsang, KY., et al. 1986. Immunol Lett. 12: 195-200. PMID: 2424829
  5. Isoprinosine restores in vitro T lymphocyte functions of cyclophosphamide immunosuppressed mice.  |  Barasoain, I., et al. 1987. Int J Immunopharmacol. 9: 489-96. PMID: 2442109
  6. Effects of isoprinosine in animal models of depressed T-cell function.  |  Binderup, L. 1985. Int J Immunopharmacol. 7: 93-101. PMID: 2581907
  7. The effect of Isoprinosine treatment on persistent infection of Balb/c mice infected with murine gammaherpesvirus 68.  |  Janíčková, O., et al. 2017. Acta Virol. 61: 32-38. PMID: 28105852
  8. Evaluation of isoprinosine to be repurposed as an adjunct anti-tuberculosis chemotherapy.  |  Mishra, AK., et al. 2018. Med Hypotheses. 115: 77-80. PMID: 29685203
  9. Isoprinosine treatment in 18 patients with subacute sclerosing panencephalitis: a controlled study.  |  Haddad, FS. and Risk, WS. 1980. Ann Neurol. 7: 185-8. PMID: 6154441
  10. Isoprinosine as an immunopotentiator in an animal model of human osteosarcoma.  |  Tsang, KY. and Fudenberg, HH. 1981. Int J Immunopharmacol. 3: 383-9. PMID: 6174468
  11. Effect of isoprinosine on interleukin 1 and 2 production and on suppressor cell activity in pokeweed mitogen stimulated cultures of B and T cells.  |  Hersey, P., et al. 1984. Int J Immunopharmacol. 6: 321-8. PMID: 6207122
  12. Immunomodulatory activity of isoprinosine on experimental viral infections in avian models.  |  Moya, P., et al. 1984. Int J Immunopharmacol. 6: 339-43. PMID: 6207123
  13. Isoprinosine stimulates granulocyte chemiluminescence and inhibits monocyte chemiluminescence in vitro.  |  Flø, RW., et al. 1994. APMIS. 102: 249-54. PMID: 7516672
  14. Echinococcus granulosus:isoprinosine treatment of the metacestode stage.  |  Sarciron, ME., et al. 1993. Am J Trop Med Hyg. 48: 658-65. PMID: 7685983
  15. Trihexyphenidyl and isoprinosine in the treatment of subacute sclerosing panencephalitis.  |  Nunes, ML., et al. 1995. Pediatr Neurol. 13: 153-6. PMID: 8534281

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Isoprinosine, 10 mg

sc-279232
10 mg
$120.00

Isoprinosine, 100 mg

sc-279232A
100 mg
$210.00

Isoprinosine, 1 g

sc-279232B
1 g
$270.00