IRF-4 Antibody (E-7): sc-377383
- IRF-4 Antibody (E-7) is a mouse monoclonal IgG1 κ, cited in 3 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 423-449 at the C-terminus of IRF-4 of mouse origin
- recommended for detection of IRF-4 of mouse, rat and human origin by WB, IP, IF and ELISA
- TransCruz reagent for ChIP application (sc-377383 X, 200 µg/0.1 ml)
- See IRF-4 (F-4): sc-48338 for IRF-4 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for IRF-4 Antibody (E-7) for WB applications. These reagents are now offered in bundles with IRF-4 Antibody (E-7) (see ordering information below).
IRF-4 Antibody (E-7) is a mouse monoclonal IgG1 antibody that detects interferon regulatory factor-4 (IRF-4) in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). IRF-4 is a crucial transcription factor that plays a significant role in the immune response by regulating the expression of interferon and interferon-inducible genes, which are vital for the development and function of lymphocytes. IRF-4 is predominantly located in the nucleus of lymphoid cells, where IRF-4 acts as a transcriptional activator by binding to the interferon-stimulated response element (ISRE) of the major histocompatibility complex (MHC) class I promoter. Proper functioning of IRF-4 is essential for the immune system′s ability to respond to pathogens and maintain immune homeostasis, making IRF-4 a key player in both adaptive and innate immunity. Additionally, IRF-4 interacts with various proteins, including PU.1, which is important for the differentiation of B cells and T cells, further underscoring IRF-4′s significance in immune regulation. IRF-4 antibody (E-7) is an invaluable tool for researchers studying immune responses, lymphocyte development, and related pathologies.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
IRF-4 Antibody (E-7) | sc-377383 | 200 µg/ml | $322.00 | |||
IRF-4 Antibody (E-7): m-IgG Fc BP-HRP Bundle | sc-540712 | 200 µg Ab; 10 µg BP | $361.00 | |||
IRF-4 Antibody (E-7): m-IgG1 BP-HRP Bundle | sc-542315 | 200 µg Ab; 20 µg BP | $361.00 | |||
IRF-4 (E-7) Neutralizing Peptide | sc-377383 P | 100 µg/0.5 ml | $69.00 | |||
IRF-4 Antibody (E-7) X | sc-377383 X | 200 µg/0.1 ml | $322.00 |