Date published: 2025-9-7

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IRAK-1 抗体 (B-8): sc-515499

4.5(2)
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说明书
  • IRAK-1 抗体 B-8 是小鼠单克隆 IgG2a,提供 200 µg/ml
  • 特异性抗原位于human物种的IRAK-1的C-terminus的氨基酸692-712之间
  • 推荐用于 human 来源的IRAK-1 WB, IP, IF 和 ELISA检测
  • 看 IRAK-1 (F-4): sc-5288,可查看有标记的 IRAK-1 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgG Fc BP-HRP是IRAK-1 Antibody (B-8) 适用于 WB 应用。 的首选辅助检测试剂。该试剂现与IRAK-1 Antibody (B-8) 搭配使用(请参阅下面的订购信息)。

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    IRAK-1抗体(B-8)是一种小鼠单克隆IgG2a抗体,可通过蛋白质印迹(WB)、免疫沉淀(IP)、免疫荧光(IF)和酶联免疫吸附测定(ELISA)等方法检测人类样本中的IRAK-1。IRAK-1在免疫反应中起着至关重要的作用,是白细胞介素-1(IL-1)受体激活的信号通路中的关键介质。当IL-1与其受体结合时,IRAK-1被吸引到受体复合物中,从而激活下游信号级联,包括NF-kB通路,该通路对于促炎细胞因子的转录至关重要。IRAK-1的正常运作对于免疫反应的强度至关重要,而IRAK-1的失调与多种炎症性疾病和病症有关,这凸显了IRAK-1作为治疗靶点的重要性。此外,IRAK-1还与TRAF6和MyD88等几种其他蛋白相互作用,这些蛋白对于IL-1信号级联的传播至关重要。IRAK-1能够与这些蛋白质形成复合物,这凸显了IRAK-1在调节炎症反应和维持免疫稳态方面的核心作用。

    仅限研究使用。不适用于诊断和治疗用途。

    订购信息

    产品名称产品编号规格价格数量收藏夹

    IRAK-1 抗体 (B-8)

    sc-515499
    200 µg/ml
    $316.00

    IRAK-1 (B-8): m-IgG Fc BP-HRP 套装

    sc-541061
    200 µg Ab; 10 µg BP
    $354.00

    IRAK-1 (B-8) 中和勝肽

    sc-515499 P
    100 µg/0.5 ml
    $68.00

    What application is the blocking peptide sc-515499 P appropriate for?

    Asked by: cjMara
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Answered by: Technical Support
    Date published: 2017-02-28
    • y_2025, m_9, d_7, h_4CST
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    Rated 4 out of 5 by from goodworks well for WB by human samples from Hep3B and 293 cells
    Date published: 2016-12-05
    Rated 5 out of 5 by from Excellentwe tried this antibody for western blots with rat brain samples. it worked very well and there are no non-specific bands or background.
    Date published: 2016-11-18
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    IRAK-1 抗体 (B-8) is rated 4.5 out of 5 by 2.
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