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Integrin β4 Antibody (H-1) is a mouse monoclonal IgG1 antibody that detects Integrin β4 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Integrin β4, also known as CD104, is a crucial component of the integrin family, consisting of 1,822 amino acids and functioning as a single-pass type I membrane protein. Anti-Integrin β4 antibody (H-1) plays a vital role in studying cell adhesion and signaling, primarily by detecting a receptor for Laminin, which is essential for maintaining the structural integrity of epithelial tissues. The interaction between Integrin β4 and Laminin is critical for processes such as cell migration, differentiation, and tissue repair, highlighting its importance in both normal physiology and pathological conditions. Notably, Integrin β4 is predominantly expressed in epithelial cells and exists in five alternatively spliced isoforms, all encoded by a gene located on human chromosome 17q25.1. Integrin β4 monoclonal antibody (H-1) provides a reliable tool for researchers studying the dynamics of cell adhesion and the extracellular matrix, facilitating advancements in understanding various diseases, including cancer and fibrosis.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Integrin β4/ITGB4/CD104 Antibody (H-1) | sc-55514 | 200 µg/ml | $322.00 | |||
Integrin β4/ITGB4/CD104 Antibody (H-1): m-IgG Fc BP-HRP Bundle | sc-537060 | 200 µg Ab; 10 µg BP | $361.00 | |||
Integrin β4/ITGB4/CD104 Antibody (H-1): m-IgGκ BP-HRP Bundle | sc-534246 | 200 µg Ab; 40 µg BP | $361.00 | |||
Integrin β4/ITGB4/CD104 Antibody (H-1): m-IgG1 BP-HRP Bundle | sc-544981 | 200 µg Ab; 20 µg BP | $361.00 |