Ibandronic Acid (CAS 114084-78-5)

物理状态 :

Solid

溶解度 :

Soluble in Aqueous Base, and water (slightly).

保存 :

Store at -20° C

熔点 :

118-121° C

沸点 :

~587.8° C at 760 mmHg

密度 :

~1.5 g/cm³ (Predicted)

折射率 :

n²⁰_D 1.54 (Predicted)

IC50 :

FDPS: IC₅₀ = 20 nM (human); Squalene synthetase: IC₅₀ = 640 nM (rat); Trypanosoma brucei rhodesiense: IC₅₀ = 960 nM; Entamoeba histolytica: IC₅₀ = 54 µM; HFF: IC₅₀ = 54.92 µM (human)

Ki 数据 :

FDPS: K_i= 3.6 nM (human)

pK值 :

pK_a: 1.6 (Predicted), pK_b: 9.5 (Predicted)

PubChem CID :

MDL 号码 :

MFCD00868772

SMILES :

CCCCCN(C)CCC(O)(P(=O)(O)O)P(=O)(O)O