Date published: 2025-9-6

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HLA class I 抗体 (HP-1F7): sc-69892

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说明书
  • HLA class I 抗体 HP-1F7 是小鼠单克隆 IgG1 κ,HLA class I抗体, 在7篇文献中引用,规格为200 µg/ml
  • 针对human来源NK细胞
  • HLA class I 抗体 (HP-1F7) 推荐用于WB, IP 和 FCM,检测human 来源的 all classical HLA class Ia as well as HLA-B (MHC class Ib)
  • 抗HLA class I抗体(HP-1F7)可与琼脂糖结合用于IP;与HRP结合用于WB、IHC(P)和ELISA;与藻红蛋白FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594Alexa Fluor® 647,用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统,例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680Alexa Fluor® 790, 用于WB (NIR), IF 和 FCM; 以及用于近红外(NIR)检测系统,如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 还提供无叠氮化物,用于对抗NK抑制受体与I类分子相互作用的实验,sc-69892 L,200 µg/0.1 ml
  • 关于如何获取HLA class I (HP-1F7): sc-69892免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgG Fc BP-HRP1 BP-HRP">m-IgG1 BP-HRPm-IgGκ BP-HRP是HLA class I Antibody (HP-1F7) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与HLA class I Antibody (HP-1F7) 打包提供(请参阅下面的订购信息)。

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関連項目

HLA I 类抗体(HP-1F7)是一种小鼠单克隆 IgG1 kappa 轻链抗体,专门设计用于识别和结合人类白细胞抗原(HLA)I 类蛋白质,也称为主要组织相容性复合体(MHC)I 类分子。这些 HLA I 类蛋白质是免疫系统不可或缺的组成部分,它们位于几乎所有有核细胞的表面,向细胞毒性 T 淋巴细胞展示内源性肽抗原。这种功能对免疫监视至关重要,能检测和消除受感染的细胞或恶性细胞,从而防止自身免疫反应和控制感染。抗 HLA I 类抗体(HP-1F7)是针对人源自然杀伤(NK)细胞制备的,对自然构象下的原生 HLA I 类蛋白具有亲和力。HLA I 类 (HP-1F7) 抗体在各种应用中都有可靠的表现,包括免疫印迹 (WB)、免疫沉淀 (IP) 和流式细胞术 (FCM),使其成为研究免疫反应、自身免疫和移植相容性的重要工具。通过靶向 HLA I 类分子,HLA I 类单克隆抗体(HP-1F7)有助于探索抗原递呈机制和不同免疫细胞之间的相互作用,从而促进我们对免疫调节和治疗开发的理解。抗 HLA I 类抗体(HP-1F7)可检测多种经典的 HLA I 类等位基因,提高了它在基础和临床研究中的应用,并能在不同的实验平台上提供一致且可重复的结果。HLA I 类 (HP-1F7) 单克隆抗体有非共轭型和多种共轭型,包括辣根过氧化物酶 (HRP)、藻红蛋白 (PE)、异硫氰酸荧光素 (FITC) 和多种 Alexa Fluor® 共轭物,可灵活满足不同的研究需求,确保免疫学研究的全面性。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

HLA class I 抗体 (HP-1F7) 参考文献:

  1. HLA I 类和 II 类基因及分子的多态性和进化。  |  Little, AM. and Parham, P. 1999. Rev Immunogenet. 1: 105-23. PMID: 11256568
  2. 控制 MHC 分子与肽组装的辅助蛋白质。  |  Van Kaer, L. 2001. Immunol Res. 23: 205-14. PMID: 11444385
  3. 泛 HLA I 类反应性单克隆抗体 W6/32 识别的表位及其与 HLA-B27/beta2 微球蛋白复合物异常稳定性的关系。  |  Tran, TM., et al. 2001. Immunogenetics. 53: 440-6. PMID: 11685454
  4. 大鼠(Rattus norvegicus)的主要组织相容性复合体。  |  Günther, E. and Walter, L. 2001. Immunogenetics. 53: 520-42. PMID: 11685465
  5. HLA 复合体的分子遗传学。  |  Fischer, GF. and Mayr, WR. 2001. Wien Klin Wochenschr. 113: 814-24. PMID: 11732117

订购信息

产品名称产品编号规格价格数量收藏夹

HLA class I 抗体 (HP-1F7)

sc-69892
200 µg/ml
$316.00

HLA class I (HP-1F7): m-IgG Fc BP-HRP 套装

sc-528651
200 µg Ab; 10 µg BP
$354.00

HLA class I (HP-1F7): m-IgGκ BP-HRP 套装

sc-521088
200 µg Ab, 40 µg BP
$354.00

HLA class I (HP-1F7): m-IgG1 BP-HRP 套装

sc-543053
200 µg Ab; 20 µg BP
$354.00

HLA class I 抗体 (HP-1F7) L

sc-69892 L
200 µg/0.1 ml
$316.00

HLA class I 抗体 (HP-1F7) AC

sc-69892 AC
500 µg/ml, 25% agarose
$416.00

HLA class I 抗体 (HP-1F7) HRP

sc-69892 HRP
200 µg/ml
$316.00

HLA class I 抗体 (HP-1F7) FITC

sc-69892 FITC
200 µg/ml
$330.00

HLA class I 抗体 (HP-1F7) PE

sc-69892 PE
200 µg/ml
$343.00

HLA class I 抗体 (HP-1F7) Alexa Fluor® 488

sc-69892 AF488
200 µg/ml
$357.00

HLA class I 抗体 (HP-1F7) Alexa Fluor® 546

sc-69892 AF546
200 µg/ml
$357.00

HLA class I 抗体 (HP-1F7) Alexa Fluor® 594

sc-69892 AF594
200 µg/ml
$357.00

HLA class I 抗体 (HP-1F7) Alexa Fluor® 647

sc-69892 AF647
200 µg/ml
$357.00

HLA class I 抗体 (HP-1F7) Alexa Fluor® 680

sc-69892 AF680
200 µg/ml
$357.00

HLA class I 抗体 (HP-1F7) Alexa Fluor® 790

sc-69892 AF790
200 µg/ml
$357.00

I have done computational analysis for HLA-A*01:01 interaction with peptide LSWEMELAY, now I want to validate it experimentally. Can I use HLA class I Antibody (HP-1F7): sc-69892 for my study?

Asked by: SHILPA
Thank you for your inquiry. The exact epitope for this antibody has not been mapped, so I am unable to answer if this antibody will interact with the peptide you are inquiring about.
Answered by: Tech Service
Date published: 2020-02-07

Can HLA class I (HP-1F7): sc-69892 monoclonal antibody be used in IF or IHC with mouse tissue or cells? Will there be non-specific staining?

Asked by: Randy McDonald
Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent, HLA class I (HP-1F7): sc-69892 is available in a variety of direct conjugations, such as HRP, PE, FITC and AlexaFluors.
Answered by: Technical Support
Date published: 2017-02-24
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Rated 5 out of 5 by from FACS on HFFThis antibody works very well in Flow cytometry on HFF cells at dilution 1:200
Date published: 2018-11-01
Rated 5 out of 5 by from Various publishable data in FCM using human jurkatVarious publishable data in FCM using human jurkat, RPMI,PBMC,COS-7, NK-92, IM-9, MOLP-8, HL60, JEG-3 cells. -SCBT Publication Review
Date published: 2015-04-01
Rated 4 out of 5 by from Robust bands detected in WB using NCIRobust bands detected in WB using NCI-H929 and U-937 whole cell lysates. -SCBT QC
Date published: 2015-02-08
Rated 5 out of 5 by from Produced excellent indirect FCM data forProduced excellent indirect FCM data for human peripheral blood leukocytes stained with HLA class I . -SCBT QC
Date published: 2013-03-04
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HLA class I 抗体 (HP-1F7) is rated 4.8 out of 5 by 4.
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