Date published: 2025-9-7
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Histone Deacetylase 1 (HDAC1) Antibody (H-11) - Western Blotting - Image 376371
HDAC1 抗体 (H-11): sc-8410. CCRF-CEM (A), PC-12 (B), C6 (C) 和 TK-1 (D) 全细胞裂解液中 HDAC1 表达的 Western 印迹分析.
HDAC1 抗体 (H-11): sc-8410. CCRF-CEM (A), PC-12 (B), C6 (C) 和 TK-1 (D) 全细胞裂解液中 HDAC1 表达的 Western 印迹分析.

Histone Deacetylase 1 (HDAC1) 抗体 (H-11): sc-8410

4.5(13)
寫評論提問

说明书
  • Histone Deacetylase 1 (HDAC1)抗体(H-11)是小鼠单克隆IgG1 κ, 在98篇文献中引用，规格为200 µg/ml
  • 免疫human来源HDAC1位于C-terminus 的432-482氨基酸
  • 抗-Histone Deacetylase 1 (HDAC1) 抗体 (H-11) 推荐用于 WB, IP, IF, FCM 和 ELISA，检测mouse, rat 和human 来源的 HDAC1
  • 抗Histone Deacetylase 1 (HDAC1)抗体（H-11）可与琼脂糖结合用于IP；与HRP结合用于WB、IHC(P)和ELISA；与藻红蛋白或FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 和 Alexa Fluor® 647，用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统，例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680 和 Alexa Fluor® 790， 用于WB (NIR), IF 和 FCM; 以及用于近红外（NIR）检测系统，如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 可用于ChIP的TransCruz试剂(sc-8410 X, 200 µg/0.1 ml)
  • 关于如何获取Histone Deacetylase 1 (HDAC1) (H-11): sc-8410的免费10 µg小样，联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • 1 BP-HRP">m-IgG1 BP-HRP是Histone Deacetylase 1 (HDAC1) Antibody (H-11) 适用于 WB 应用。 的首选辅助检测试剂。该试剂现与Histone Deacetylase 1 (HDAC1) Antibody (H-11) 打包提供（请参阅下面的订购信息）。

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相关产品
描述
基因信息
蛋白序列
说明书与实验方案
研究信息

関連項目

额外HDAC抗体，包括HDAC1, HDAC10, HDAC11, HDAC2, HDAC3, HDAC4, HDAC5, HDAC6, HDAC7, HDAC8和HDAC9

HDAC1抗体（H-11）是一种小鼠单克隆IgG1 kappa轻链抗体，专门设计用于靶向人类HDAC1的C端区域，识别氨基酸432-482。HDAC1单克隆抗体（H-11）具有跨物种反应性，可有效检测小鼠、大鼠和人类样本中的HDAC1，适用于多种应用，包括蛋白质印迹（WB）、免疫沉淀（IP）、免疫荧光（IF）、流式细胞术（FCM）和酶联免疫吸附测定（ELISA）。HDAC1小鼠单克隆抗体（H-11）有非结合型和多种结合型，如琼脂糖、HRP、PE、FITC和多种Alexa Fluor®结合型，为不同的实验需求提供了多种选择。HDAC1，也称为GON-10、HD1、KDAC1、RPD3和RPD3L1，通过从组蛋白蛋白上的赖氨酸残基上移除乙酰基来调节染色质结构，从而在基因表达调控中发挥关键作用，导致染色质凝结和转录抑制。这种酶活性对于细胞周期进展、分化和发展等过程至关重要。HDAC1参与维持基因组稳定性和调节各种信号通路。HDAC1失调与多种疾病有关，包括癌症、神经疾病和炎症，因此HDAC1是治疗干预的重要靶标和表观遗传学研究的重点。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

订购信息

产品名称产品编号规格价格数量收藏夹

Histone Deacetylase 1 抗体 (H-11)

sc-8410
200 µg/ml
$316.00

Histone Deacetylase 1 (HDAC1) (H-11): m-IgG1 BP-HRP 套装

sc-531634
200 µg Ab; 20 µg BP
$354.00

Histone Deacetylase 1 (HDAC1) 抗体 (H-11) X

sc-8410 X
200 µg/0.1 ml
$316.00

Histone Deacetylase 1 (HDAC1) 抗体 (H-11) AC

sc-8410 AC
500 µg/ml, 25% agarose
$416.00

Histone Deacetylase 1 (HDAC1) 抗体 (H-11) HRP

sc-8410 HRP
200 µg/ml
$316.00

Histone Deacetylase 1 (HDAC1) 抗体 (H-11) FITC

sc-8410 FITC
200 µg/ml
$330.00

Histone Deacetylase 1 (HDAC1) 抗体 (H-11) PE

sc-8410 PE
200 µg/ml
$343.00

Histone Deacetylase 1 (HDAC1) 抗体 (H-11) Alexa Fluor® 488

sc-8410 AF488
200 µg/ml
$357.00

Histone Deacetylase 1 (HDAC1) 抗体 (H-11) Alexa Fluor® 546

sc-8410 AF546
200 µg/ml
$357.00

Histone Deacetylase 1 (HDAC1) 抗体 (H-11) Alexa Fluor® 594

sc-8410 AF594
200 µg/ml
$357.00

Histone Deacetylase 1 (HDAC1) 抗体 (H-11) Alexa Fluor® 647

sc-8410 AF647
200 µg/ml
$357.00

Histone Deacetylase 1 (HDAC1) 抗体 (H-11) Alexa Fluor® 680

sc-8410 AF680
200 µg/ml
$357.00

Histone Deacetylase 1 (HDAC1) 抗体 (H-11) Alexa Fluor® 790

sc-8410 AF790
200 µg/ml
$357.00

What negative control should be used when using the conjugated version of this antibody in flow cytometry?

Asked by: TinTin
Thank you for your inquiry. We recommend using the isotype specific normal mouse IgG conjugated to the same fluorophore. For example, if you are using sc-107 PE, then you would want to use normal mouse IgG1 PE, sc-2866.
Answered by: Tech Service
Date published: 2017-02-01
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Rated 5 out of 5 by from Quite good antibody1:200 diluted for wb of rat protein ,the band is quite strong and special!
Date published: 2017-12-31
Rated 4 out of 5 by from a relatively good antibody for WBThis antibody generates a clear signal at the predicted position on the western blot (1:500 dilution, 40ug HeLa extract).
Date published: 2017-09-01
Rated 4 out of 5 by from Epigenetic Modulation of Human Podocyte Vitamin Dwe studied the effect of HIV on expression of molecules involved in SNAIL repressor complex formation and demonstrated that HIV enhances expression of the histone deacetylase HDAC1 and DNA methyl transferases DNMT3b and DNMT1. 293T cells, when stably transfected with SNAIL (SNAIL/293T), displayed suppressed transcription and translation of VDR. In SNAIL/293T cells, co-immunoprecipitation studies revealed the association of HDAC1, DNMT3b, DNMT1, and mSin3A with SNAIL. Chromatin immunoprecipitation experiments confirmed the presence of the SNAIL repressor complex at the VDR promoter. Our findings demonstrate that SNAIL recruits multiple chromatin enzymes to form a repressor complex in HIV milieu that down regulates VDR expression.
Date published: 2017-08-08
Rated 4 out of 5 by from Band at 60KDa as expectedA strong band was at 60KDa as expected; however, it needs to be confirmed with blocking peptide.
Date published: 2017-06-30
Rated 4 out of 5 by from Superb product !!Strong western blot results; clear, specific signal; also nice IHC staining data
Date published: 2017-01-30
Rated 5 out of 5 by from Great HDAC1 antibodyGreat antibody with strong data in WB, flow cytometry, and ChIP. Well-cited antibody recommended for mouse, rat, and human detection.
Date published: 2017-01-24
Rated 2 out of 5 by from HDAC1- reviewWorks at 1:1000 dilution on 10 ug MDA-MB-231 lysate, although other unidentifiable bands seen
Date published: 2016-12-12
Rated 5 out of 5 by from good stainingThis antibody gave a good staining by IF anaysis human tissue samples at dilution 1:200,I always get expected staining.
Date published: 2016-12-02
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Histone Deacetylase 1 (HDAC1) 抗体 (H-11) is rated 4.5 out of 5 by 13.
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