Date published: 2025-9-7
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GSK3 alpha/beta Antibody (0011-A) - Western Blotting - Image 281956
GSK-3α/β 抗体 (0011-A): sc-7291. MCF7 (A), SK-BR-3 (B), A549 (C), Jurkat (D) 和 MDCK (E) 全细胞裂解液中 GSKα/β 表达的 Western 印迹分析.
GSK-3α/β 抗体 (0011-A): sc-7291. MCF7 (A), SK-BR-3 (B), A549 (C), Jurkat (D) 和 MDCK (E) 全细胞裂解液中 GSKα/β 表达的 Western 印迹分析.

GSK3 alpha/beta 抗体 (0011-A): sc-7291

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说明书
  • GSK3 alpha/beta 抗体 0011-A 是小鼠单克隆 IgG2a κ，GSK3 alpha/beta抗体, 在276篇文献中引用，规格为200 µg/ml
  • 与氨基酸反应 1-420 代表Xenopus laevis起源的全长糖原合酶激酶-3 beta
  • GSK3 alpha/beta 抗体 (0011-A) 推荐用于 WB, IP, IF, IHC(P) 和 FCM，检测mouse, rat, human, canine 和Xenopus 来源的 GSK-3α and GSK-3β
  • 抗GSK3 alpha/beta抗体（0011-A）可与琼脂糖结合用于IP；与HRP结合用于WB、IHC(P)和ELISA；与藻红蛋白或FITC结合用于IF、IHC(P)和FCM
  • 还可偶联Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 和 Alexa Fluor® 647，用于WB (RGB), IF, IHC(P) 和 FCM, 以及用于RGB荧光成像系统，例如iBright™ FL1000, FluorChem™, Typhoon, Azure和其他类似的系统
  • 还可偶联Alexa Fluor® 680 和 Alexa Fluor® 790， 用于WB (NIR), IF 和 FCM; 以及用于近红外（NIR）检测系统，如LI-COR®/Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure和类似系统
  • 关于如何获取GSK3 alpha/beta (0011-A): sc-7291的免费10 µg小样，联系我们技术服务部门 (或者您当地的代理商)了解详情。
  • m-IgGκ BP-HRP 是 GSK3 alpha/beta 抗体 (0011-A) 在 WB and IHC(P) 应用中的首选二抗检测试剂。该试剂现与GSK3 alpha/beta 抗体 (0011-A) 组合成套装提供。 (请参阅下面的订购信息)。其他m-IgGκ BP 偶联产品，请参阅我们的小鼠 IgG 结合蛋白完整列表。

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描述
基因信息
说明书与实验方案
研究信息

関連項目

额外GSK抗体，包括GSK-3 β

GSK-3α/β抗体（0011-A）是一种小鼠单克隆IgG2a kappa轻链抗体，可通过蛋白质印迹（WB）、免疫沉淀（IP）、免疫荧光（IF）、免疫组织化学和流式细胞术（FCM）检测小鼠、大鼠、人、犬和非洲爪蟾来源的GSK-3α/β蛋白。GSK-3α/β抗体（0011-A）有非结合型和多种结合型可供选择，包括琼脂糖、辣根过氧化物酶（HRP）、藻红蛋白（PE）、异硫氰酸荧光素（FITC）和多种Alexa Fluor®结合物。糖原合酶激酶3（GSK-3）是一种丝氨酸/苏氨酸激酶，在多种信号传导通路中发挥着关键作用，尤其是涉及糖原代谢和细胞粘附的信号通路，与阿尔茨海默病的发病机制有关。GSK-3有两种同工型，即GSK-3α和GSK-3β，它们在亚细胞定位方面存在差异，GSK-3α主要存在于细胞质中，而GSK-3β则同时存在于细胞质和细胞核中。这种定位差异非常重要，因为GSK-3可能会影响每种同工型所调节的特定信号通路，从而影响细胞对各种刺激的反应。GSK-3磷酸化Tau，后者是一种微管相关蛋白，可稳定神经元中的微管。阿尔茨海默病中Tau的过度磷酸化被认为是导致神经纤维缠结（该疾病的标志）形成的原因。了解GSK-3α和GSK-3β在细胞过程中的不同作用有助于阐明其对神经退行性疾病的影响，并探索潜在的治疗靶点。

仅限研究使用。不适用于诊断和治疗用途。

Alexa Fluor® 是Molecular Probes Inc., OR., USA的商标

LI-COR®和 Odyssey® 是LI-COR Biosciences的注册商标

订购信息

产品名称产品编号规格价格数量收藏夹

GSK3 alpha/beta 抗体 (0011-A)

sc-7291
200 µg/ml
$316.00

GSK3 alpha/beta (0011-A): m-IgGκ BP-HRP 套装

sc-520486
200 µg Ab, 40 µg BP
$354.00

GSK3 alpha/beta 抗体 (0011-A) AC

sc-7291 AC
500 µg/ml, 25% agarose
$416.00

GSK3 alpha/beta 抗体 (0011-A) HRP

sc-7291 HRP
200 µg/ml
$316.00

GSK3 alpha/beta 抗体 (0011-A) FITC

sc-7291 FITC
200 µg/ml
$330.00

GSK3 alpha/beta 抗体 (0011-A) PE

sc-7291 PE
200 µg/ml
$343.00

GSK3 alpha/beta 抗体 (0011-A) Alexa Fluor® 488

sc-7291 AF488
200 µg/ml
$357.00

GSK3 alpha/beta 抗体 (0011-A) Alexa Fluor® 546

sc-7291 AF546
200 µg/ml
$357.00

GSK3 alpha/beta 抗体 (0011-A) Alexa Fluor® 594

sc-7291 AF594
200 µg/ml
$357.00

GSK3 alpha/beta 抗体 (0011-A) Alexa Fluor® 647

sc-7291 AF647
200 µg/ml
$357.00

GSK3 alpha/beta 抗体 (0011-A) Alexa Fluor® 680

sc-7291 AF680
200 µg/ml
$357.00

GSK3 alpha/beta 抗体 (0011-A) Alexa Fluor® 790

sc-7291 AF790
200 µg/ml
$357.00

Anti-GSK-3α/β Antibody (0011-A): sc-7291. Is this antibody yeast reactive?

Asked by: MichaelS
Yeast Reactivity validation is untested and unknown.
Answered by: Tech Sales
Date published: 2021-06-25

How should the cells be fixed for flow cytometry?

Asked by: tubensalami
Thank you for your question. We recommend using a fixation buffer to fix cells for Flow cytometry. Our buffer can be found here: FCM Fixation Buffer (sc-3622) : https://www.scbt.com/scbt/product/fcm-fixation-buffer Our recommended protocol is here: https://www.scbt.com/scbt/resources/protocols/flow-cytometry If you have any further questions, please contact our European Technical Service team. You can reach them by phone at Toll Free: +49 6221 4503 0, by email at: europe@scbt.com or by live chat directly on our website, www.scbt.com
Answered by: Tech Service
Date published: 2017-10-10

Can I use this mouse monoclonal antibody for immunohistochemical staining of mouse tissue?

Asked by: Cweed
You definitely can. We recommend using a directly conjugated primary antibody. SC-7291 is available directly conjugated to AF488, AF647, and FITC.
Answered by: TechService7
Date published: 2016-12-21

What is the recommended secondary reagent to be used with this mouse monoclonal primary?

Asked by: Cweed
We recommend using one our exclusive Mouse IgG Binding Proteins as a secondary detection reagent. A complete list of available binding proteins is available on our website here: https://www.scbt.com/scbt/browse/support-products-mouse-igg-binding-proteins/_/N-ecrety
Answered by: TechService7
Date published: 2016-12-21
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Rated 5 out of 5 by from works goodworks at 1:100 with milk as blocking buffer and primary incubation overnight at 4 degree. 1hr RT secondary incubation at 1:2000 dilution
Date published: 2024-01-02
Rated 5 out of 5 by from perfect antibodyworks very well and detects proteins with no background
Date published: 2023-11-14
Rated 5 out of 5 by from Good antibody for WBI used this antibody diluted 1:500 in milk/TBST buffer, loading 30ug of total protein. The signal is strong, clean bands without any background.
Date published: 2021-06-22
Rated 5 out of 5 by from A clean and potent antibodyWe purchased the antibody last month for quantification of GSK by Western blotting. We are able to detect both GSK isoforms from HepG2 cells using 2 mcg antibody per blot. Non-specific band was not detected. This is an excellent antibody.
Date published: 2019-10-24
Rated 5 out of 5 by from good productIt works pretty well for our western blot experiment.
Date published: 2018-08-22
Rated 4 out of 5 by from Great antibodiesI got a free sample from company. I used antibodies in WB in dilution 1:1000. It works good.
Date published: 2018-07-14
Rated 5 out of 5 by from Great antibody for western blotThe batch of antibody I have worked well on BJAB, HeLa, MCF7, NIH/3T3, Jurkat and K562 total cell extracts for western Blot. The band is specific. The antibody was diluted 250 times into 5% BSA, TBST and incubated over-night at 4°C.
Date published: 2018-01-04
Rated 5 out of 5 by from Super anticorps !!J'ai tester cet échantillon en WB 1/500 et il marche super bien, signal très spécifique, sans bruit de fond (membrane strippé et réutilisé déjà 3 fois!!).
Date published: 2017-11-30
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GSK3 alpha/beta 抗体 (0011-A) is rated 4.9 out of 5 by 48.
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