Date published: 2025-9-7

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GRK 2 抗体 (F-9): sc-166284

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说明书
  • GRK 2抗体(F-9)是小鼠单克隆IgG1 κ, 在2篇文献中引用,规格为200 µg/ml
  • 特异性抗原位于human物种的GRK 2的C-terminus附近的氨基酸661-699之间
  • 推荐用于 mouse, rat 和 human 来源的GRK 2 WB, IP, IF 和 ELISA检测; 也和以下物种反应,包括: 和 canine and porcine
  • 看 GRK 2 (C-9): sc-13143,可查看有标记的 GRK 2 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • m-IgG Fc BP-HRP1 BP-HRP">m-IgG1 BP-HRPm-IgGκ BP-HRP是GRK 2 Antibody (F-9) 适用于 WB 应用。 的首选辅助检测试剂。这些试剂现与GRK 2 Antibody (F-9) 打包提供(请参阅下面的订购信息)。

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异源三聚体G蛋白介导的信号转导是一个动态调节的过程,尽管激动剂持续存在,但信号强度随时间降低。这一现象被称为激动剂介导的去敏化,涉及两类酶对受体的磷酸化。第一类是由第二信使调节的激酶,如c-AMP依赖的蛋白激酶A和蛋白激酶C。第二类包括G蛋白偶联受体激酶(GRKs)。GRK家族中至少已鉴定出七个成员。这些包括视紫红质激酶(GRK 1)、两种形式的β-肾上腺素能受体激酶:GRK 2 (βARK、βARK1)和GRK 3 (βARK2)、IT-11 (GRK 4)、GRK 5、GRK 6和GRK 7。GRKs对受体的磷酸化似乎严格依赖于受体处于其激动剂激活状态。

仅限研究使用。不适用于诊断和治疗用途。

订购信息

产品名称产品编号规格价格数量收藏夹

GRK 2 抗体 (F-9)

sc-166284
200 µg/ml
$316.00

GRK 2 (F-9): m-IgG Fc BP-HRP 套装

sc-537469
200 µg Ab; 10 µg BP
$354.00

GRK 2 (F-9): m-IgGκ BP-HRP 套装

sc-534745
200 µg Ab; 40 µg BP
$354.00

GRK 2 (F-9): m-IgG1 BP-HRP 套装

sc-545197
200 µg Ab; 20 µg BP
$354.00

GRK 2 (F-9) 中和勝肽

sc-166284 P
100 µg/0.5 ml
$68.00

What application is the blocking peptide sc-166284 P appropriate for?

Asked by: jenniferc
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-24
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Rated 5 out of 5 by from Good choice for WBThe (F-9) clone is a very good choice for Western blotting, but alternative product GRK 2 Antibody (C-9): sc-13143 has very strong in-house for Western blotting, and it has been featured in over a dozen publications.
Date published: 2017-02-07
Rated 5 out of 5 by from Western blot publication using human andWestern blot publication using human and rat mesenteric artery -SCBT Publication Review
Date published: 2015-04-03
Rated 5 out of 5 by from Signal via western blot analysis of GRK 2Signal via western blot analysis of GRK 2 expression in non-transfected: sc-117752 and human GRK 2 transfected: sc-172730 293T whole cell lysates. -SCBT QC
Date published: 2015-03-09
Rated 5 out of 5 by from Western blot publication using SHWestern blot publication using SH-SY5Y samples -SCBT QC -SCBT Publication Review
Date published: 2015-02-26
Rated 5 out of 5 by from Signal via western blot analysis of GRK 2Signal via western blot analysis of GRK 2 expression in non-transfected 293T: sc-117752, human GRK 2 transfected 293T: sc-115352 and Ramos whole cell lysates. -SCBT QC
Date published: 2015-02-13
Rated 5 out of 5 by from Signal via western blot analysis of GRK 2Signal via western blot analysis of GRK 2 expression in non-transfected: sc-117752 and human GRK 2 transfected: sc-111619 293T whole cell lysates. -SCBT QC -SCBT QC
Date published: 2015-01-23
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GRK 2 抗体 (F-9) is rated 5.0 out of 5 by 6.
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