Date published: 2025-9-7

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GRK 2 抗体 (E-7): sc-166283

4.0(1)
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说明书
  • GRK 2抗体(E-7)是小鼠单克隆IgG2b (kappa轻链),规格为200 µg/ml
  • 特异性抗原位于human物种的GRK 2的C-terminus的氨基酸661-689之间
  • 推荐用于 mouse, rat 和 human 来源的GRK 2 WB, IP, IF 和 ELISA检测; 也和以下物种反应,包括: 和 canine and porcine
  • 看 GRK 2 (C-9): sc-13143,可查看有标记的 GRK 2 抗体,包括AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 和 790
  • 目前,我们还没有完成GRK 2 抗体 (E-7)的首选二抗检测试剂的鉴定。这项工作正在进行中。

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    関連項目

    异源三聚体G蛋白介导的信号转导是一个动态调节的过程,尽管激动剂持续存在,但信号强度随时间降低。这一现象被称为激动剂介导的去敏化,涉及两类酶对受体的磷酸化。第一类是由第二信使调节的激酶,如c-AMP依赖的蛋白激酶A和蛋白激酶C。第二类包括G蛋白偶联受体激酶(GRKs)。GRK家族中至少已鉴定出七个成员。这些包括视紫红质激酶(GRK 1)、两种形式的β-肾上腺素能受体激酶:GRK 2 (βARK、βARK1)和GRK 3 (βARK2)、IT-11 (GRK 4)、GRK 5、GRK 6和GRK 7。GRKs对受体的磷酸化似乎严格依赖于受体处于其激动剂激活状态。

    仅限研究使用。不适用于诊断和治疗用途。

    订购信息

    产品名称产品编号规格价格数量收藏夹

    GRK 2 抗体 (E-7)

    sc-166283
    200 µg/ml
    $316.00

    GRK 2 (E-7) 中和勝肽

    sc-166283 P
    100 µg/0.5 ml
    $68.00

    What application is the blocking peptide sc-166283 P appropriate for?

    Asked by: Professor Griffin
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Answered by: Technical Support
    Date published: 2017-03-01
    • y_2025, m_9, d_6, h_5CST
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    Rated 4 out of 5 by from Positive signal via western blot analysisPositive signal via western blot analysis of GRK 2 expression in non-transfected: sc-117752 and human GRK 2 transfected: sc-111619 293T whole cell lysates. -SCBT QC
    Date published: 2013-06-10
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    GRK 2 抗体 (E-7) is rated 4.0 out of 5 by 1.
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